Inside Front Cover: Selective Construction of Supramolecular Nanotube Hosts with Cationic Inner Surfaces (Adv. Mater. 22/2005)

Selective construction of a supramolecular nanotube host with a cationic inner surface consisting of unsymmetrical bolaamphiphiles is reported on p. 2732 by Masuda, Shimizu, and co‐workers. The nanotube, shown schematically on the inside cover, has different inner and outer surfaces covered with amino and sugar functionalities, respectively, and is able to effectively encapsulate anionic nanomaterials, such as sulfate‐latex beads (see TEM image) and spherical proteins, in the cationic hollow cylinder without depending on capillary action.     

Étude des paramètres de fabrication d'un béton de bois à matrice argileuse

The subject of the present study is to highlight the use of clay waste resulting from the operations of aggregate quarries through developing lightened clayey concretes. The lightening is achieved by adding wood aggregates, which are waste materials from woodworking activities. The authors account for the influence of components on the mechanical characteristics of hardened concretes and on the behaviour of the material just after mixing. They propose a formulation allowing the development a dry material with a volumic weight equal to 800 kg/m³ and a compressive strength, at hydrous stability, equal to 2.5 MPa offering the possibility tof being poured easily. Attempts at treating wood aggregates have proved the necessity for a systematic study to take into account the specificity of clay.     

Eriodictyol Protects Endothelial Cells against Oxidative Stress-Induced Cell Death through Modulating ERK/Nrf2/ARE-Dependent Heme Oxygenase-1 Expression

The pathophysiology of cardiovascular diseases is complex and may involve oxidative stress-related pathways. Eriodictyol is a flavonoid present in citrus fruits that demonstrates anti-inflammatory, anti-cancer, neurotrophic, and antioxidant effects in a range of pathophysiological conditions including vascular diseases. Because oxidative stress plays a key role in the pathogenesis of cardiovascular disease, the present study was designed to verify whether eriodictyol has therapeutic potential. Upregulation of heme oxygenase-1 (HO-1), a phase II detoxifying enzyme, in endothelial cells is considered to be helpful in cardiovascular disease. In this study, human umbilical vein endothelial cells (HUVECs) treated with eriodictyol showed the upregulation of HO-1 through extracellular-regulated kinase (ERK)/nuclear factor erythroid 2-related factor 2 (Nrf2)/antioxidant response element (ARE) signaling pathways. Further, eriodictyol treatment provided protection against hydrogen peroxide-provoked cell death. This protective effect was eliminated by treatment with a specific inhibitor of HO-1 and RNA interference-mediated knockdown of HO-1 expression. These data demonstrate that eriodictyol induces ERK/Nrf2/ARE-mediated HO-1 upregulation in human endothelial cells, which is directly associated with its vascular protection against oxidative stress-related endothelial injury, and propose that targeting the upregulation of HO-1 is a promising approach for therapeutic intervention in cardiovascular disease.     

Ventilation and energy performance of partitioned indoor spaces under mixing and displacement ventilation

Large variation in indoor air quality (IAQ) and thermal comfort can occur in partitioned office spaces due to heterogeneous air mixing. However, few published studies examined IAQ, thermal comfort, and energy performance of partitioned occupied spaces, which are commonly found in today’s buildings. The objective of this study is to evaluate indoor environmental quality and air conditioning performance of a partitioned room under two typical ventilation modes: (1) mixing ventilation and (2) displacement ventilation. For a total of six representative air-conditioning scenarios, three-dimensional computational fluid dynamics (CFD) simulations are performed to examine temperature distribution, ventilation effectiveness, energy consumption, and local thermal comfort for two partitioned spaces. Simulation results indicate that temperature distribution in a partitioned room is a strong function of ventilation strategy (mixing vs. displacement), but marginally affected by diffuser arrangements. Local age-of-air (air freshness) significantly varies with both diffuser arrangement and ventilation strategy. Regarding energy consumption, displacement ventilation can achieve an indoor set-point temperature in the partitioned spaces about two times faster than mixing ventilation. Under mixing ventilation, the time to achieve a set-point temperature was notably reduced when each partitioned space is served by its own diffuser. For the same supply airflow rate, displacement ventilation can generate local draft risk at ankle level, while mixing ventilation may result in a draft sensation in wider areas around an occupant. Overall, the results suggest that mixing ventilation system can save energy if each partitioned zone is served by its own diffuser such as a multi-split air conditioning. However, when multiple partitioned zones are served by only one diffuser, displacement ventilation is more energy-efficient and can achieve higher ventilation effectiveness than mixing ventilation.     

Word Sense Disambiguation Using the Classification Information Model

A Classification Information Model is a pattern classification model.The model decides the proper class of an input instance by integrating individual decisions, each of which is made with each feature in the pattern.Each individual decision is weighted according to the distributional property of the feature deriving the decision. An individual decision and its weight are represented as classification information which is extracted from the training instances.In the word sense disambiguation based on the model, the proper sense of an input instance is determined by the weighted sum of whole individual decisions derived from the features contained in the instance.     

Explaining radical group behavior: Developing emotion and efficacy routes to normative and nonnormative collective action.

A recent model of collective action distinguishes 2 distinct pathways: an emotional pathway whereby anger in response to injustice motivates action and an efficacy pathway where the belief that issues can be solved collectively increases the likelihood that group members take action (van Zomeren, Spears, Fischer, & Leach, 2004). Research supporting this model has, however, focused entirely on relatively normative actions such as participating in demonstrations. We argue that the relations between emotions, efficacy, and action differ for more extreme, nonnormative actions and propose (a) that nonnormative actions are often driven by a sense of low efficacy and (b) that contempt, which, unlike anger, entails psychological distancing and a lack of reconciliatory intentions, predicts nonnormative action. These ideas were tested in 3 survey studies examining student protests against tuition fees in Germany (N = 332), Indian Muslims' action support in relation to ingroup disadvantage (N = 156), and British Muslims' responses to British foreign policy (N = 466). Results were generally supportive of predictions and indicated that (a) anger was strongly related to normative action but overall unrelated or less strongly related to nonnormative action, (b) contempt was either unrelated or negatively related to normative action but significantly positively predicted nonnormative action, and (c) efficacy was positively related to normative action and negatively related to nonnormative action. The implications of these findings for understanding and dealing with extreme intergroup phenomena such as terrorism are discussed. (PsycINFO Database Record (c) 2011 APA, all rights reserved)     

Relationship between Geriatric Nutritional Risk Index and total lymphocyte count and mortality of hemodialysis patients

We examined the relationships between Geriatric Nutritional Risk Index (GNRI), total lymphocyte count (TLC), and mortality in hemodialysis (HD) patients. We examined GNRI and TLC in 120 maintenance HD patients and followed these patients for 120 months. Predictors of all‐cause death were examined using life table analysis and the Cox proportional hazards model. TLC marginally correlated with GNRI (r = 0.176; p = 0.090) and significantly with phosphorus levels (r = 0.206; p = 0.026). Life table analysis revealed that subjects with a GNRI < 90 (n = 19) had lower survival rates than did those with a GNRI ≥ 90 (n = 101; Wilcoxon's test, p = 0.048), but subjects with a TLC < 1500/mm³ (n = 76) had similar survival rates compared with subjects with a TLC ≥ 1500/mm³ (n = 44; Wilcoxon's test, p = 0.500). Multivariate Cox proportional hazards analyses demonstrated that GNRI is a significant predictor of mortality (hazard ratio 9.315, 95% confidence interval 1.161–74.753, p = 0.036), after adjusting for age, sex, presence of type 2 diabetes mellitus, Kt/V, normalized protein catabolic rate, hematocrit, phosphorus, systolic blood pressure and TLC. Our findings suggest the TLC may be used as a simple nutritional tool, but may not be a predictor of mortality in HD patients. These findings require confirmation by further studies.     

Synthesis and characterization of 2,1,3-benzothiadiazole-thieno[3,2-b]thiophene-based charge transferred-type polymers for photovoltaic application

New low-band-gap copolymers, including thieno[3,2-b]thiophene and 2,1,3-benzothiadiazole, were synthesized as photovoltaic materials. Thiophene was introduced to provide extended π-conjugation length and charge transfer properties. A band gap (E_g^op=1.62 eV, E_g^ec=1.51 eV) of this polymer was investigated through UV-vis spectroscopy and cyclic voltammetry. A bulk heterojunction structure of glass/indium tin oxide (ITO)/PEDOT:PSS/polymer-PCBM(1:3)/LiF/Al was fabricated for investigating photovoltaic properties. PC₇₁BM was used as an acceptor material, due to its increased absorption in the visible region, in comparison with PC₆₁BM. In this polymer, incident photon-to-current conversion efficiency (IPCE) was as high as 50%. Moreover, maximum power conversion efficiency (PCE) of up to 1.72% was achieved under AM 1.5 G conditions. It demonstrated relatively high V_OC (0.67 V) and J_SC (6.86 mA/cm²), while a low fill factor value (0.37) was obtained.     

Measurement of the effect of self-heating in strained-siliconMOSFETs

The self-heating of strained-silicon MOSFETs is demonstrated experimentally. Output characteristics measured by a pulse technique, in which self-heating is absent, show as much as 15% greater drain current (for 15% Ge content) than the corresponding static measurements. Comparison of the current measured this way with the static measurements allows an estimate of the channel temperature during the static operation. The temperature rise is compared to a simple estimate of the thermal resistance of the FET