Analysis of a resonant-cavity enhanced GaAs/AlGaAs MSMphotodetector

The authors have developed a 2-D device simulator for heterostructure metal-semiconductor-metal (MSM) photodetectors. They have incorporated a model of multilayer optics into the simulator and used it to analyze the temporal response of a resonant-cavity enhanced heterostructure with a confining buffer layer and a distributed Bragg reflector (DBR). The authors show that through fine tuning the layer thicknesses, optical resonance enhancement of the light absorption can be obtained     

Diffraction characteristics of superimposed holographic gratings inplanar optical waveguides

A coupled-mode analysis of superimposed holographic transmission gratings in single-mode planar optical waveguides is presented. The diffraction characteristics are shown to be sensitive to the polarization of the incident wave, the angular separation of the output waves and the relative index modulation between the gratings. The coupling between gratings affects the diffraction efficiencies and decreases the angular and wavelength selectivities. Nevertheless, good channel separation and high fanout can be obtained together     

光孤子相互作用对压缩态的影响

在线性近似条件下，量子化了非线性薛定谔方程，用后向传播法数值求解了光孤子相互作用对压缩比的影响。数值结果表明，在碰撞距离附近，压缩比显著增加。     

Inhibition of G1 cyclin-dependent kinase activity during growth arrest of human breast carcinoma cells by prostaglandin A2

Prostaglandin A2 (PGA2) potently inhibits cell proliferation and suppresses tumor growth in vivo, but little is known regarding the molecular mechanisms mediating these effects. Here we demonstrate that treatment of breast carcinoma MCF-7 cells with PGA2 leads to G1 arrest associated with a dramatic decrease in the levels of cyclin D1 and cyclin-dependent kinase 4 (cdk4) and accompanied by an increase in the expression of p21. We further show that these effects occur independent of cellular p53 status. The decline in cyclin D and cdk4 protein levels is correlated with loss in cdk4 kinase activity, cdk2 activity is also significantly inhibited in PGA2-treated cells, an effect closely associated with the upregulation of p21. Immunoprecipitation experiments verified that p21 was indeed complexed with cdk2 in PGA2-treated cells. Additional experiments with synchronized MCF-7 cultures stimulated with serum revealed that treatment with PGA2 prevents the progression of cells from G1 to S. Accordingly, the kinase activity associated with cdk4, cyclin E, and cdk2 immunocomplexes, which normally increases following serum addition, was unchanged in PGA2-treated cells. Furthermore, the retinoblastoma protein (Rb), a substrate of cdk4 and cdk2 whose phosphorylation is necessary for cell cycle progression, remains underphosphorylated in PGA2-treated serum-stimulated cells. These findings indicate that PGA2 exerts its growth-inhibitory effects through modulation of the expression and/or activity of several key G1 regulatory proteins. Our results highlight the chemotherapeutic potential of PGA2, particularly for suppressing growth of tumors lacking p53 function.     

美籍华裔专家讲通信工程技术新动态

本文扼要介绍１９９５年北京中美工程技术研讨会通信组五位美籍华裔专家关于通信技术新动态的专题报告。一是宽带综合业务数字网的同步数字系列（ＳＤＨ）和异步转移模式（ＡＴＭ）；二是光纤通信系统的光放大器（ＯＦＡ）、波分多路（ＷＤＭ）、光电子集成（ＯＥＩＣ）、色散补偿和新型光纤；三是蜂窝网车载移动通信和全国性个人通信业务（ＰＣＳ）、时分多址（ＴＤＭＡ）和码分多址（ＣＤＭＡ），四是智能网（ＩＮ）体系结构、概念模型和业务管理系统（ＳＭＳ）；五是数字传输网的恢复（ＦＡＳＴＡＲ）、维护（ＴＭＰ）和供应（ＴＳＮＯＷ）三种管理平台，及综合网络管理系统（ＩＮＭＳ）。     

c-KIT expression enhances the leukemogenic potential of 32D cells

The growth of human leukemic cells in culture and in vivo is dependent upon the presence of hematopoietic growth factors. Most populations of human leukemic acute myeloblastic leukemia (AML) cells express c-Kit on their surface and respond to Kit ligand (KL) in culture. To determine if this interaction was of potential significance in vivo we used a mouse model system. 32D cells, a murine IL-3-dependent myeloid cell line, were rendered KL responsive by transfection of the murine c-Kit. After injection of 32D or 32D-Kit cells into syngeneic hosts, animals bearing 32D-Kit cells, but not 32D cells, became moribund and were killed. These animals had circulating leukemic blast cells, infiltration of bone marrow, spleen, brain, liver, lung, and kidney. Cells recovered from some of the animals continued to be dependent upon IL-3 or KL for growth while in other cases the cells were factor independent. This model illustrates that the constitutive expression of c-Kit enhances the leukemic potential of 32D cells. The model will be useful for studying the progression of leukemia in vivo and testing whether interruption of the interaction of Kit and KL can affect the growth of leukemic cells.     

ZnO陶瓷材料的负阻特性

介绍了ＺｎＯ陶瓷的负阻特性，主要研究了ＭｎＯ２掺杂和Ｎｉ２Ｏ３掺杂对ＺｎＯ陶瓷负阻特性的影响。     

Performance analysis of the bidirectional associative memory and animproved model from the matched-filtering viewpoint

This paper discusses the bidirectional associative memory (BAM) model from the matched-filtering viewpoint and offers it a new interpretation. Our attention is focused on the problem of stability and attractivity of equilibrium states. Several sufficient and/or necessary conditions are presented. To improve the BAM performance, an exponential function is used to enhance the correlations between the binary vectors of the retrieval key and that of the stored pattern similar to the key. The modified model is shown to be asymptotically stable. Theoretical analysis and simulation results demonstrate that the modified model performs much better than the original BAM in terms of memory capacity and error correction capability.