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991.
992.
PCI接口卡硬件与驱动程序设计 总被引:6,自引:0,他引:6
介绍了一种较为通用的PCI接口卡的硬件结构,说明了硬件设计的几种可行性方案和硬件设计时需要注意的问题,同时详细地阐述了PCI设备WDM驱动程序开发的基本方法,比较了几种常用开发工具的优缺点,并对驱动程序中的PCI设备I/O端口与存储器的读写、中断处理以及应用程序与驱动程序之间多种通信方式作了详细的介绍。 相似文献
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雷达检测数据的连续性对于雷达航迹跟踪来说是非常重要的,根据观测目标特性的不同,中断检测时长不同会造成不同程度的航迹误跟、漏跟甚至失跟。分析了在某些特定情况下出现雷达检测中断后对航迹处理造成的影响,针对常规航迹跟踪处理方法,从原理上对中断检测对航迹连续带来的问题进行了详细分析,设计并实现了一种检测中断前后航迹连续跟踪算法,获得了较为满意的效果,并通过仿真和实测数据的处理验证了方法的有效性。 相似文献
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Analysis of FMRI data using an integrated principal component analysis and supervised affinity propagation clustering approach 总被引:1,自引:0,他引:1
Zhang J Tuo X Yuan Z Liao W Chen H 《IEEE transactions on bio-medical engineering》2011,58(11):3184-3196
Clustering analysis is a promising data-driven method for analyzing functional magnetic resonance imaging (fMRI) time series data. The huge computational load, however, creates practical difficulties for this technique. We present a novel approach, integrating principal component analysis (PCA) and supervised affinity propagation clustering (SAPC). In this method, fMRI data are initially processed by PCA to obtain a preliminary image of brain activation. SAPC is then used to detect different brain functional activation patterns. We used a supervised Silhouette index to optimize clustering quality and automatically search for the optimal parameter p in SAPC, so that the basic affinity propagation clustering is improved by applying SAPC. Four simulation studies and tests with three in vivo fMRI datasets containing data from both block-design and event-related experiments revealed that functional brain activation was effectively detected and different response patterns were distinguished using our integrated method. In addition, the improved SAPC method was superior to the k -centers clustering and hierarchical clustering methods in both block-design and event-related fMRI data, as measured by the average squared error. These results suggest that our proposed novel integrated approach will be useful for detecting brain functional activation in both block-design and event-related experimental fMRI data. 相似文献
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Debadrita Paria Annalisa Convertino Piyush Raj Kristine Glunde Yun Chen Ishan Barman 《Advanced functional materials》2021,31(30):2101638
Nanotechnology has provided tools for next generation biomedical devices which rely on nanostructure interfaces with living cells. In vitro biomimetic structures have enabled observation of cell response to various mechanical and chemical cues, and there is a growing interest in isolating and harnessing the specific cues that 3D microenvironments can provide without the requirement for such culture and the experimental drawbacks associated with it. Here, a randomly oriented gold coated Si nanowire substrate with patterned hydrophobic–hydrophilic areas for the differentiation of isogenic breast cancer cells of varying metastatic potential is reported. When considering synthetic surfaces for the study of cell-nanotopography interfaces, randomly oriented nanowires more closely resemble the isotropic architecture of a natural extracellular matrix. In the study reported here, the authors show that primary cancer cells preferably attach to the hydrophilic region of randomly oriented nanowire substrate while secondary cancer cells do not adhere. Using machine learning analysis of fluorescence images, cells are found to spread and elongate on the nanowire substrates as compared to a flat substrate, where they mostly remain round. Such platforms can not only be used for developing bioassays but also as stepping stones for tissue printing technologies where cells can be selectively patterned at desired locations. 相似文献
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Gunhyu Bae Yoo Sang Jeon Min Jun Ko Yuri Kim Seong-Beom Han Ramar Thangam Wonsik Kim Hee Joon Jung Sungkyu Lee Hyojun Choi Sunhong Min Hyunsik Hong Sangwoo Park Seong Yeol Kim Kapil D. Patel Na Li Jeong Eun Shin Bum Chul Park Hyeon Su Park Jun Hwan Moon Yu Jin Kim Uday Kumar Sukumar Jae-Jun Song Soo Young Kim Seung-Ho Yu Yun Chan Kang Steve Park Seung Min Han Dong-Hwee Kim Ki-Bum Lee Qiang Wei Liming Bian Ramasamy Paulmurugan Young Keun Kim Heemin Kang 《Advanced functional materials》2021,31(37):2103409
Developing materials with the capability of changing their innate features can help to unravel direct interactions between cells and ligand-displaying features. This study demonstrates the grafting of magnetic nanohelices displaying cell-adhesive Arg-Gly-Asp (RGD) ligand partly to a material surface. These enable nanoscale control of rapid winding (“W”) and unwinding (“UW”) of their nongrafted portion, such as directional changes in nanohelix unwinding (lower, middle, and upper directions) by changing the position of a permanent magnet while keeping the ligand-conjugated nanohelix surface area constant. The unwinding (“UW”) setting cytocompatibility facilitates direct integrin recruitment onto the ligand-conjugated nanohelix to mediate the development of paxillin adhesion assemblies of macrophages that stimulate M2 polarization using glass and silicon substrates for in vitro and in vivo settings, respectively, at a single cell level. Real time and in vivo imaging are demonstrated that nanohelices exhibit reversible unwinding, winding, and unwinding settings, which modulate time-resolved adhesion and polarization of macrophages. It is envisaged that this remote, reversible, and cytocompatible control can help to elucidate molecular-level cell–material interactions that modulate regenerative/anti-inflammatory immune responses to implants. 相似文献