Comparative Characteristics of the Structure and Physicochemical Properties of Silica Synthesized by Pyrogenic and Fluoride Methods

Silicon - This paper presents the comparative analysis of the properties of highly dispersed silicas synthesized by pyrogenic and fluoride methods. Raw materials and synthesis conditions differ...     

Modification of Nonionic Vesicles by Adding Decanol and Functional Lanthanide Ions

Colloid systems modified by luminescent ions in situ are highly attractive for the design of new molecular architectures and adaptable for monitoring and visualizing soft drug delivery systems. This paper presents original results on the characterization of the self‐organization process and the structure of vesicles formed by tetraethylene glycol monodecyl ether (C₁₂EO₄) in the presence of lanthanide ions and decanol additives. Detailed characterization of surface activity, aggregation properties and microstructure of individual and mixed aggregates has been carried out based on surface tension, electron microscopy, small‐angle X‐ray scattering, dynamic light scattering analysis and fluorescence spectroscopy. The small‐angle scattering results in combination with quantum‐chemical calculations assume the multishell vesicle formation in C₁₂EO₄/C₁₀H₂₁OH/H₂O media. In the C₁₂EO₄ solution the presence of Ln(III) ions and decanol initiate the formation of multilamellar vesicles with a size of about 100 nm. The luminescence analysis of the Eu(III) and Tb(III) complexes has shown the efficient solubilization in the C₁₂EO₄/C₁₀H₂₁OH/H₂O vesicles, which leads to increase in the lifetime. The resulting outcome is the possibility to control micro and macro properties of a molecular organized system to give it the desired functionality.     

Structure–properties investigations in hydrophilic nanocomposites based on polyurethane/poly(2–hydroxyethyl methacrylate) semi‐interpenetrating polymer networks and nanofiller densil for biomedical application

Nanocomposites based on sequential semi–interpenetrating polymer networks (semi–IPNs) of crosslinked polyurethane and linear poly(2‐hydroxyethyl methacrylate) filled with 1–15 wt % of nanofiller densil were prepared and investigated. Nanofiller densil used in an attempt to control the microphase separation of the polymer matrix by polymer–filler interactions. The morphology (SAXS, AFM), mechanical properties (stress–strain), thermal transitions (DSC) and polymer dynamics (DRS, TSDC) of the nanocomposites were investigated. Special attention has been paid to the raising of the hydration properties and the dynamics of water molecules in the nanocomposites in the perspective of biomedical applications. Nanoparticles were found to aggregate partially for higher than 3 and 5 wt % filler loading in semi–IPNs with 17 and 37 wt % PHEMA, respectively. The results show that the good hydration properties of the semi–IPN matrix are preserved in the nanocomposites, which in combination with results of thermal and dielectric techniques revealed also the existence of polymer–polymer and polymer–filler interactions. These interactions results also in the improvement of physical and mechanical properties of the nanocomposites in compare with the neat matrix. The improvement of mechanical properties in combination with hydrophilicity and biocompatibility of nanocomposites are promising for use these materials for biomedical application namely as surgical films for wound treatment and as material for producing the medical devises. © 2015 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2016 , 133, 43122.     

Analysis of a Hyperbolic System Modelling the Thermoelastic Impact of Two Rods

The problem on collinear collision of two thermoelastic rods possessing the same rheological parameters but of different length and temperature is considered, in so doing before the impact the rods move unidirectionally along a common longitudinal axis with distinct constant velocities. Lateral surfaces and free ends of both rods are heat insulated, and free heat exchange between the rods occurs within contacting ends. The rods' thermoelastic behavior is described by the Green–Naghdy theory. Two methods are used as the methods of solution, namely: D'Alembert's method and the ray method. D'Alembert's method is based on the analytical solution of equations of the hyperbolic type describing the dynamic behavior of the thermoelastic rods. This solution involves four arbitrary functions which are determined from the initial and boundary conditions and are piecewise constant functions. The ray method is based on the theory of discontinuities and also allows one to obtain the solution involving four arbitrary constants. Both solutions complement each other, since D'Alembert's solution enables one to analyze the influence of thermoelastic parameters on the values to be found, while the solution via the ray method is best suited for numerical investigation of the longitudinal coordinate dependence of the desired values at each fixed instant of the time beginning from the moment of rods' collision up to the moment of their rebound. To illustrate the both approaches, the problem of the rods' collision without account for the stress and temperature fields coupling is also considered.     

Numerical Analysis of Quasioptical Multireflector Antennas in 2-D With the Method of Discrete Singularities: E-Wave Case

Numerical method for modeling the E-polarized wave scattering by electrically large quasioptical two-dimensional (2-D) reflectors is presented. Reflectors are assumed zero-thickness and perfectly electrically conducting. Efficient numerical solution is obtained from the coupled singular integral equations discretized using new quadrature formulas of interpolation type. It has controlled accuracy and deals with small-size matrices. To simulate a small-horn feeding, the incident field is taken as a beam generated by a complex-source-point (CSP) current. Presented numerical results validate empirical rule of -10 dB edge illumination needed to provide the best electromagnetic performance of reflector     

Light‐Controlled Reversible Manipulation of Microgel Particle Size Using Azobenzene‐Containing Surfactant

The light‐induced reversible switching of the swelling of microgel particles triggered by photo‐isomerization and binding/unbinding of a photosensitive azobenzene‐containing surfactant is reported. The interactions between the microgel (N‐isopropylacrylamide, co‐monomer: allyl acetic acid, crosslinker: N,N′‐methylenebisacrylamide) and the surfactant are studied by UV‐Vis spectroscopy, dynamic and electrophoretic light scattering measurements. Addition of the surfactant above a critical concentration leads to contraction/collapse of the microgel. UV light irradiation results in trans‐cis isomerization of the azobenzene unit incorporated into the surfactant tail and causes an unbinding of the more hydrophilic cis isomer from the microgel and its reversible swelling. The reversible contraction can be realized by blue light irradiation that transfers the surfactant back to the more hydrophobic trans conformation, in which it binds to the microgel. The phase diagram of the surfactant‐microgel interaction and transitions (aggregation, contraction, and precipitation) is constructed and allows prediction of changes in the system when the concentration of one or both components is varied. Remote and reversible switching between different states can be realized by either UV or visible light irradiation.     

Study of hemocompatibility and endothelial cell interaction of tecoflex-based electrospun vascular grafts

Abstract

Ensuring long-term functioning and efficient endothelialization of small diameter vascular grafts (VG) is an urgent task of tissue engineering. A solution may be to use electrospun VGs prepared from blends polyurethane with gelatin and/or bivalirudin. Here, properties of 3D matrices were explored by SEM, contact angle measurements and IR spectroscopy, and their interaction with blood and endothelial cells was studied. Introduction of gelatin into matrices enhanced adhesion and proliferation of endotheliocytes and enabled adhesion of platelets, whereas bivalirudin inhibited platelet adhesion while having no negative effect on the adhesion and proliferation of endothelial cells.     

Effect of pH,co-monomer content,and surfactant structure on the swelling behavior of microgel-azobenzene-containing surfactant complex

The contraction/swelling transition of anionic PNIPAM-co-AAA particles can be manipulated by light using interactions with cationic azobenzene-containing surfactant. In this study the influence of pH-buffers and their concentrations, the charge density (AAA content) in microgel particles as well as the spacer length of the surfactant on the complex formation between the microgel and surfactant is investigated. It is shown that the presence of pH buffer can lead to complete blocking of the interactions in such complexes and the resulting microgel contraction/swelling response. There is a clear competition between the buffer ions and the surfactant molecules interacting with microgel particles. When working in pure water solutions with fixed concentration (charge density) of microgel, the contraction/swelling of the particles is controlled only by relative concentration (charge ratio) of the surfactant and AAA groups of the microgel. Furthermore, the particle contraction is more efficient for shorter spacer length of the surfactant. The onset point of the contraction process is not affected by the surfactant hydrophobicity. This work provides new insight into the interaction between microgel particles and photo-sensitive surfactants, which offers high potential in new sensor systems.     

Do automated program repair techniques repair hard and important bugs?

Existing evaluations of automated repair techniques focus on the fraction of the defects for which the technique can produce a patch, the time needed to produce patches, and how well patches generalize to the intended specification. However, these evaluations have not focused on the applicability of repair techniques and the characteristics of the defects that these techniques can repair. Questions such as “Can automated repair techniques repair defects that are hard for developers to repair?” and “Are automated repair techniques less likely to repair defects that involve loops?” have not, as of yet, been answered. To address such questions, we annotate two large benchmarks totaling 409 C and Java defects in real-world software, ranging from 22K to 2.8M lines of code, with measures of the defect’s importance, the developer-written patch’s complexity, and the quality of the test suite. We then analyze relationships between these measures and the ability to produce patches for the defects of seven automated repair techniques —AE, GenProg, Kali, Nopol, Prophet, SPR, and TrpAutoRepair. We find that automated repair techniques are less likely to produce patches for defects that required developers to write a lot of code or edit many files, or that have many tests relevant to the defect. Java techniques are more likely to produce patches for high-priority defects. Neither the time it took developers to fix a defect nor the test suite’s coverage correlate with the automated repair techniques’ ability to produce patches. Finally, automated repair techniques are less capable of fixing defects that require developers to add loops and new function calls, or to change method signatures. These findings identify strengths and shortcomings of the state-of-the-art of automated program repair along new dimensions. The presented methodology can drive research toward improving the applicability of automated repair techniques to hard and important bugs.