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51.
The authors examined a community-based sample of 303 clinically nondepressed individuals aged 75 through 96 years on 4 recall tasks: free recall of rapidly presented random words, free recall of slowly presented random words, free recall of organizable words, and cued recall of organizable words. Using a classification taxonomy that identified mood- and motivation-related symptoms of depression, it was found that motivation-related symptoms had a negative effect on performance across all tasks, whereas mood-related symptoms had no effects. In addition, motivation-related symptoms negatively influenced the ability to benefit from more study time but had no effect on the ability to make use of item organization or category cues. An analysis of the specific motivation-related symptoms suggested that symptoms that may affect the ability to focus and sustain attention (e.g., concentration difficulties, lack of interest ) were most strongly associated with performance deficits. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
52.
Mothers of 45 control and 35 clinic children (mean ages 7.6 and 7.5 yrs, respectively) completed 2 factor-analytically derived rating scales of child psychopathology, the Behavior Problem Checklist and the Parent Questionnaire. Intercorrelations among factors indicated some factor overlap and some differences between apparently similar factors. Conduct problem ratings on the Behavior Problem Checklist covaried with ratings of conduct problems, hyperactivity, and learning problems on the Parent Questionnaire. Patterns of correlations suggested that mothers of nonreferred children rated pathology per se, whereas mothers of referred children rated behaviors that fell into internalizing and externalizing clusters. Teachers asked to rate 22 referred and 22 control males (mean ages 8.3 and 8.5 yrs, respectively) on the Behavior Problem Checklist and the Teacher Rating Scale showed more consistency in the behaviors rated. It is concluded that, although similar factor labels are used from scale to scale, they reflect somewhat different behaviors and are influenced by the child's clinical status, the rater's past experience with children, and specific scale characteristics. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
53.
Joseph Sampugna Luise Light Mary G. Enig D. Yvonne Jones Joseph T. Judd Elaine Lanza 《Lipids》1988,23(2):131-136
Analysis of cheek cell lipids has been suggested as a noninvasive method for monitoring the fatty acid composition of diets
in humans. In a pilot study conducted to determine the validity of the method, cheek cell samples were collected from subjects
consuming a low fat (20% of calories) diet consisting of fatty acids with either a 1.0 or 0.3 P/S ratio. Neither total lipid
nor polar lipid fatty acids in cheek cells consistently reflected the P/S ratio of the diets. However, there were trends,
particularly in the nonpolar lipids, suggesting that cheek cell fatty acid ratios might be useful for monitoring the fatty
acid composition of the diets. The diet with the higher P/S ratio (1.0 vs 0.3) consistently resulted in cheek cell lipids
with lower ratios of 18∶1/saturated fatty acids and greater 18∶2/20∶4, 18∶2/18∶1 and 18∶2/18∶0 fatty acid ratios. 相似文献
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A metal-dependent dipeptidase has been purified from a cell-free extract of Lactobacillus delbrueckii subsp. bulgaricus B14 by ammonium sulphate precipitation, anion exchange chromatography, metal chelating affinity chromatography with immobilized Cu2+, and repeated FPLC anion exchange chromatography. The molecular mass of the purified enzyme was estimated to be 51 kD by SDS-polyacrylamide gel electrophoresis as well as by gel filtration, which indicates that it does not consist of subunits. The enzyme was most active at pH 7 and 50°C. Reducing agents, like dithiothreitol and β-mercaptoethanol, increased enzyme activity while metal chelating agents had an inhibitory effect. Enzyme activity, inhibited by EDTA and EGTA, could be partially restored by Co2+ and Mn2+. The enzyme was most active on dipeptides containing an aminoterminal hydrophobic amino acid such as Leu-Leu and Leu-Gly. Kinetic studies indicated that the dipeptidase had a higher affinity for the first substrate mentioned. The Km-values for both substrates were about 0·56 and 1·23 mM, with turnover numbers of 870 and 480 s−1, respectively. 相似文献
56.
Mara Dobroschke Yvonne Geldmacher Ingo Ott Dr. Melanie Harlos Lisa Kater Laura Wagner Ronald Gust Prof. Dr. William S. Sheldrick Prof. Dr. Aram Prokop Dr. 《ChemMedChem》2009,4(2):177-187
Whereas the cytostatic agents mer‐[RhX3(DMSO)(pp)] (X=Cl, Br; pp=phen, dpq) are considerably more potent than their facial isomers, this order is reversed for the analogous kinetically more inert IrIII polypyridyl complexes. The complexes induce specific apoptotic cell death in leukemia and lymphoma cells via the intrinsic mitochondrial pathway and cause negligible necrotic damage.
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Eleven surfactants representing pure cationic, anionic and nonionic detergents, four commercial detergents, sodium pyrophosphate, sodium tripolyphosphate, a soap and nitrilotriacetic acid (NTA) were investigated for their effect on the determination of aluminium in water using the eriochrome cyanine R, ferron-orthophenanthroline and chrome azurol S methods. Cationic, anionic and nonionic detergents at concentrations up to 2, 100 and 1000 mg l−1, respectively, did not interfere. Sodium tripolyphosphate interfered badly above 1.0 mg l−1, and therefore the interference by formulated detergents containing tripolyphosphate was serious. Concentrations of NTA, soap and sodium pyrophosphate had to be below 0.5, 10 and 20 mg l−1, respectively, to limit the error to 5%. 相似文献
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