Coping with Hydrological Extremes

Abstract

Coping with hydrological extremes, floods, and droughts has been a major concern since the dawn of human civilization. Freshwater, a necessary condition of life and a raw material used in very high volumes in virtually every human activity, is becoming increasingly scarce. Water use has risen considerably in the last hundred years at a pace exceeding the population growth. Therefore, societies are increasingly vulnerable to droughts and water deficits. Although the 21st century is heralded as the age of water scarcity, flood losses continue to grow. Increasing global vulnerability results to a large extent from soaring anthropopressure: settlements in hazardous locations and adverse land use changes. Deforestation and urbanization lead to reduction of the storage volume and higher values of runoff coefficient. In more wealthy countries, it is the material flood losses that continue to grow, while the number of fatalities goes down. Advanced flood preparedness systems can save lives and reduce human suffering. In some regions of the world, long-term forecasts (e.g., ENSO) help improve the preparedness for hydrological extremes, both floods and droughts, and hopefully will even more so in the future. Scenarios for future climate indicate the possibility of sharpening the extremes and changes of their seasonality. For instance, in Western Scotland and Norway, an increase of winter floods has already been observed. According to recent assessments, there is a growing risk of summer droughts in the Mediterranean region: less precipitation in summer and higher temperature will coincide, causing higher evapo-transpiration and less runoff. Fighting with floods and droughts has not been quite successful. Humans have to get used to the fact that extreme hydrological events are natural phenomena that will continue to occur. While doing one's best to improve the preparedness systems, it is necessary to learn to live with hydrological extremes.     

Evolutionary algorithms for constrained engineering problems

Evolutionary computation techniques have been receiving increasing attention regarding their potential as optimization techniques for complex problems. Recently these techniques were applied in the area of industrial engineering; the most-known applications include scheduling and sequencing in manufacturing systems, computer-aided design, facility layout and location problems, distribution and transportation problems, and many others. Industrial engineering problems usually are quite hard to solve due to a high complexity of the objective functions and a significant number of problem-specific constraints; often an algorithm to solve such problems requires incorporation of some heuristic methods. In this paper we concentrate on constraint handling heuristics for evolutionary computation techniques. This general discussion is followed by three test case studies: truss structure optimization problem, design of a composite laminated plate, and the unit commitment problem. These are typical highly constrained engineering problems and the methods discussed here are directly transferrable to industrial engineering problems.     

Palladium(II) complexes adsorption from the chloride solutions with macrocomponent addition using strongly basic anion exchange resins, type 1

The use of the strongly basic anion exchange resins, type 1 such as Lewatit MP-500 and Lewatit MP-500A for palladium(II) complexes adsorption has been investigated. The adsorption process was carried out from the chloride solutions with macrocomponent (sodium chloride) addition (x M HCl–1.0 M NaCl; x M HCl–2.0 M NaCl) where the concentration of hydrochloric acid was constant and equal to x = 0; 0.1; 0.5; 1.0; and 2.0 M, respectively. The breakthrough curves of Pd(II) were determined and the sorption parameters (weight and bed distribution coefficients, working anion exchange capacity) were calculated. The pseudo-second kinetic order was applied in kinetic studies as well as to calculate the kinetic parameters. The values of the working anion exchange capacities (0.029 g/cm³; 0.028 g/cm³) for Lewatit MP-500 and Lewatit MP-500A (0.028 g/cm³; 0.027 g/cm³) in the 1.0 M NaCl and 0.1 M HCl–1.0 M NaCl solutions, respectively are really close and in other solutions under discussion Lewatit MP-500 possess slightly higher values of capacities, and therefore is insignificantly more efficient in the adsorption process of palladium(II) ions than Lewatit MP-500A. The equilibrium adsorption capacities changed in the range 8.84–9.99 and 8.40–9.38 mg/g for Lewatit MP-500 as well as 8.12–9.57 and 7.26–8.85 mg/g for Lewatit MP-500A in the chloride x M HCl-1.0 M NaCl and x M HCl-2.0 M NaCl solutions, respectively. The adsorption process proceeds according to the pseudo-second kinetic order.     

Image correlation technique for strain measurement of polycrystalline microstructures

An image processing technique is proposed to measure the deformation of polycrystalline materials based on correlating the grains in reference and deformed SEM images. The advantage of this technique compared to the conventional subset-based Digital Image Correlation (DIC) is that it can be applied when speckle patterning is not efficient or when studying boundary-related mechanics is the objective. The technique is based on correlating grains by defining their boundaries rather than just subsets of image pixels. It reveals the anisotropy inherent in the polycrystals since it allows the analysis to specify each grain separately without averaging the results. The technique is applied by detecting the approximate grain boundaries edges and then refining their location with high accuracy. The correlation is performed between points calculated from each grain in the reference and deformed images as a Point Set Registration (PSR) problem. Finally, the displacements and strains are calculated from the resulting transformation matrix. A benchmark problem was developed to discuss the error over a strain range of 0.02 to 0.2 and showed that the resulting strains are reasonably accurate. Also, an in situ experiment was conducted to demonstrate the implementation of the technique using a specimen with fine-grained Zirconia polycrystals. The technique successfully revealed the crack tip plastic zone, and strain mismatch between grains.     

1-Indanone and 1,3-indandione Derivatives as Ligands for Misfolded α-Synuclein Aggregates

The development of imaging agents for in vivo detection of alpha-synuclein (α-syn) pathologies faces several challenges. A major gap in the field is the lack of diverse molecular scaffolds with high affinity and selectivity to α-syn fibrils for in vitro screening assays. Better in vitro scaffolds can instruct the discovery of better in vivo agents. We report the rational design, synthesis, and in vitro evaluation of a series of novel 1-indanone and 1,3-indandione derivatives from a Structure-Activity Relationship (SAR) study centered on some existing α-syn fibril binding ligands. Our results from fibril saturation binding experiments show that two of the lead candidates compounds 8 and 32 bind α-syn fibrils with binding constants (K_d) of 9.0 and 18.8 nM, respectively, and selectivity of greater than 10× for α-syn fibrils compared with amyloid-β (Aβ) and tau fibrils. Our results demonstrate that the lead ligands avidly label all forms of α-syn on PD brain tissue sections, but only the dense core of senile plaques in AD brain tissue, respectively. These results are corroborated by ligand-antibody colocalization data from Syn211, which shows immunoreactivity toward all forms of α-syn aggregates, and Syn303, which displays preferential reactivity toward mature Lewy pathology. Our results reveal that 1-indanone derivatives have desirable properties for the biological evaluation of α-synucleinopathies.     

Breeding the Future

For Zbigniew Oksiuta energy from the sun offers the greatest potential for architecture, as the essential life-giving force for all living things. Here he urges a future of architecture that is biological, as demonstrated by his own featured bioforms that investigate the cultivation of new types of organisms and living biological products outside the confines of natural evolution. Copyright © 2009 John Wiley & Sons, Ltd.