干涉型光纤水听器灵敏度校准方法研究

研究了利用贝塞尔函数比值来估算得到干涉型光纤水听器光相移的方法,而得到光纤水听器的相移灵敏度。对理论模型进行了模拟,并对一推挽式干涉型零差光纤水听器进行了实际校准。     

变极性等离子弧焊铝合金厚板工艺研究

变极性等离子弧焊是一种新型焊接方法,由于等离子弧对焊接工艺和规范参数的变化比较敏感,获得良好焊缝接头的合理规范参数范围窄、裕度小.本文通过工艺试验,探讨了变极性等离子弧焊16mm铝合金厚板的技术可行性,论述了其相对于传统弧焊工艺的优点.     

Secreted HSP90α-LRP1 Signaling Promotes Tumor Metastasis and Chemoresistance in Pancreatic Cancer

The extracellular heat shock protein 90α (eHSP90α) has been reported to promote cancer cell motility. However, whether pancreatic cancer (PC) cells expressed membrane-bound or secreted HSP90α, as well as its underlying mechanism for PC progression, were still unclear. Our study demonstrated that the amounts of secreted HSP90α proteins were discrepant in multiple PC cells. In addition, highly invasive Capan-2 cells have a higher level of secreted HSP90α compared with those of less invasive PL45 cells. The conditioned medium of Capan-2 cells or recombinant HSP90α treatment stimulated the migration and invasion of PC cells, which could be prevented with a neutralizing anti-HSP90α antibody. Furthermore, secreted HSP90α promoted elements of epithelial–mesenchymal transition in PL45 cells, including increases in vimentin and Snail expressions, decreases in E-cadherin expression, and changes in cell shape towards a mesenchymal phenotype, but these phenomena were reversed by the anti-HSP90α antibody in Capan-2 cells. In addition, high levels of low-density lipoprotein receptor-related protein 1 (LRP1) were associated with worsened patient survival in pancreatic adenocarcinoma. We demonstrated LRP1 as a receptor of eHSP90α for its stimulatory role in metastasis, by activating the AKT pathway. In addition, silencing LRP1 enhanced the chemosensitivity to gemcitabine and doxorubicin in Capan-2 cells. Therefore, our study indicated that blocking secreted HSP90α underlies an aspect of metastasis and chemoresistance in PC.     

纳米电子器件呼唤真空化学研究

纳米电子器件是微电子器件发展的下一代 ,现有微电子器件的主要材料是极纯的硅、锗和镓砷等晶体半导体。纳米电子器件有可能是以有机或有机 /无机复合晶体薄膜为主要材料 ,要求纯度更高 ,结构更完善。真空制备的清洁环境 ,有希望加工组装出纳米电子器件所要求的结构。故本文建议开展真空化学研究     

碳纤维增强碳化硅陶瓷基复合材料的研究

使用CVD技术提高纤维增强陶瓷基复合材料的密度是很困难的,因为它很难使反应气体完全渗入到基体里面.这是由于"瓶颈"效应所致,即CVD过程阻塞了基体表面的小气孔,进而封闭了通向大气孔的入口.为此,提出一种新的方法位控CVD(PCCVD),来克服上述困难.通过控制反应气体通道位置和试样的加热位置,从而达到控制沉积位置,使沉积界面始终处于开孔状态.使用PCCVD技术制造的C/SiC复合材料,实际密度可达其理论密度的96%.     

高层建筑消防安全现状与防火方法

新时期下,我国高层建筑数量不断增多,而且建筑物仍然在向超高层、超大面积的方向发展,这给消防防火和安全管理工作提出了比较高的要求。高层建筑与多层建筑和单层建筑在结构上存在比较大的不同,必须要制定一套符合高层建筑实际需求的防火方法,全面加强消防安全监管力度,这样才能确保高层建筑的防火安全性。文章在简要分析高层建筑火灾特征,以及高层建筑消防安全现状的基础上,提出了几点有关防火安全管理的策略。     

Systematic adsorption process of petroleum hydrocarbon by immobilised petroleum-degradation bacteria system in degradation pathways

In order to effectively control petroleum hydrocarbon pollution by immobilisation technology,it is necessary to understanding the degradation pathways of petrol...     

结合二进制PSO的SVM在园林评价中的应用

根据支持向量机算法的原理,建立基于支持向量机的园林设计评价模型,通过引入二进制微粒群算法对影响园林设计的特征参数进行选择,解决了大量无关或冗余特征所造成的"维数灾难"和降低分类器性能的问题,利用SVM多类分类器实现了对园林设计的评价。实例分析表明,该方法提高了园林设计评价的准确性和可靠性。     

一致持久的带外虚拟化系统

存储虚拟化能够全面提升存储区域网络的服务质量,而带外虚拟化与带内虚拟化相比具有性能高和扩展性好等优点．提出了运用按序操作、REDO日志以及日志完整性鉴别,共同保证带外虚拟化跨越系统崩溃或断电事故后仍旧可用;设计了一种基于关系模型的磁盘上虚拟化元数据组织方式,它具有可读性好和容易修改的优点;给出了通过分析磁盘分区表兼容典型遗留存储系统的有效方法,它具有庞大遗留系统零切割时间的特点．基于上述关键技术实现的原型系统,在典型实验中表现了很好的性能．