Studies toward the synthesis of the shark repellent pavoninin-5

Sharks are the most dangerous predators of people in the sea, resulting in people being mauled and killed each year. A shark repellent could help to diminish this danger. The aglycone of the shark repellent pavoninin-5, (25R)-cholest-5-en-3β,15α,26-triol (5a), was synthesized from diosgenin (9). Removing mercury from the Clemmensen reduction of 9 gave a higher yield of (25R)-cholest-5-en-3β,16β,26-triol, 10a, and was also more environmentally friendly. Attempted methods for the transposition of the C-16β hydroxyl to the 15α position are described. A successful method for this transposition via the 15α-hydroxy-16-ketone, 8a, using the Barton deoxygenation reaction on the 16-alcohol 14b, is reported.     

论县市级中医院网络硬件基础设施的设计

我国《2006-2020年国家信息化发展战略》提出要加强卫生信息化建设;2011年3月卫生部发布《基于电子病历的医院信息平台建设技术解决方案》;2011年10月国家中医药管理局发布《中医医院信息化建设基本规范》。以上都为我国各个县级中医医院的信息化提供了技术支撑和统一要求。结合我国县市级中医医院的现状,对其网络硬件基础设施平台的设计进行探讨,以满足其发展及国家对医疗机构的信息化要求。     

基于中国电信CEP协议的组件服务应用

面对复杂多变的需求,需要我们梳理出业务的本质,并设计一套与之相适应、易扩展的框架结构,让业务组件化,组件服务化,通过灵活的服务组装,来满足灵活多样的业务需求。本文旨在通过对中国电信CEP协议的剖析,指引如何通过对整个CEP层次结构进行归纳总结,体系化实现服务能力的封装与开放。     

求解非线性互补问题的光滑化拟牛顿法

利用光滑Chen Harker KanzowSmale函数和Robinson正则法,将非线性互补问题转化为与之等价的光滑非线性方程组,并基于无导数线搜索技术提出了一种新的求解P0非线性互补问题的光滑化拟牛顿法.在一定条件下获得了算法的全局收敛性,数值实验表明该算法是有效的.     

Synthesis and characterization of polyamides based on dimer acid

A series of dimer acid-based polyamides were synthesized by melt-polycondensation of dimer acid and various aromatic diamines, and were characterized by Fourier transform infrared spectrum (FT-IR) and nuclear magnetic resonance (¹H NMR). The physical properties of the polyamides, such as glass transition temperature, melting temperature, decomposition temperature and mechanical properties were also investigated. The polyamides’ intrinsic viscosity ranges from 1.8 dL·g⁻¹ to 2.2 dL·g⁻¹, and the melting temperature ranges from 140 °C to 181 °C. The glass transition temperatures, observed from dynamic mechanical analysis, fall in the range of 34.8–48.2 °C. The physical and mechanical properties of the resultant polyamides are similar to those of the PA1212. The heat resistance and mechanical properties of poly (4, 4′-diphenylsulfone dimeramide) (PSD) and poly(4, 4′-diphenyl dimeramide) (PPDI) are comparable to those of PA1212.     

Inhibitory effect of Cr（Ⅵ） on activities of soil enzymes

To evaluate the influence of various Cr(VI) concentrations (0.05, 0.25, 0.50, 1.00 and 2.00 g/kg) on the activity of soil enzymes, the activities of catalase, polyphenol oxidase, dehydrogenase, alkaline phosphatase in soils were investigated in the incubation experiment with a period of 35 d. The results indicate that all the tested Cr(VI) concentrations significantly inhibit dehydrogenase activity by over 70% after 35 d. The activity of alkaline phosphatase is slightly inhibited during the whole experiment except for on the day 7. Cr(VI) has no obvious effect on the activity of catalase in soil. On the contrary, Cr(VI) stimulates the activity of polyphenol oxidase. The results suggest that dehydrogenase activity can be used as an indicator for assessing the severity of chromium pollution. Foundation item: Projects(2006AA06Z374, 2007AA021304) supported by the National High-Tech Research and Development Program of China; Project(2008SK2007) supported by the Key Program of Science and Technology of Hunan Province, China     

基于扩展OpenC++植入技术研究与实现

本文首先介绍了常用的植入方法并分析了优缺点,重点详细分析了基于扩展OpenC+-植入技术的实现方法。     

Survivability-oriented optimal node density for randomly deployed wireless sensor networks

The survivability is usually critical for wireless sensor networks,which are often deployed in the unattended harsh environment.Lots of technical schemes to improve the survivability depend on the redundant resources of the sensor networks.The amount of resources is usually determined by the node density during the deployment phase.For the random deployment and random node failures,the quantitative relation between the survivability and the node density is studied.Based on the conditional survivability,the node density to meet the required survivability level is presented.Finally,the survivability for unpredictable failures and the optimal node density to maximize the price–performance ratio are also discussed.     

Promotion of hydrogen permeation on metal-dispersed alumina membranes and its application to a membrane reactor for methane steam reforming

A mesoporous membrane for selective separation of hydrogen was prepared usingthe sol-gel method. Some metal salts such as RuCl₃, Pd(NH₃)₄Cl₂, RhCl₃,, and H ₂PtCl₆, were added to the boehmite sol and coated on a porous alumina substrate before firing at 500°C. It was foundthat the permeability of hydrogen and the separation factor for a hydrogen-nitrogen gaseous mixture of these metaldispersed membranes exceeded the limitations of the Knudsen diffusion mechanism. Although the gas permeation through a neat alumina membrane is governed by the Knudsen diffusion, the metals dispersed in alumina membranes were effective in promoting hydrogen permeation. These metaldispersed alumina membranes were also used in a membrane reactor for methane steam reforming at low temperature. In the temperature range of 300 to 500°C, the membrane reactor attained a methane conversion twice as high as the equilibrium value of the packed bed catalytic reactor system as a result of the selective removal of hydrogen from the reaction system.     

The Utility of Information Security Training and Education on Cybersecurity Incidents: An empirical evidence

As recent cyber-attacks have been increasing exponentially, the importance of security training for employees also has become growing ever than before. In addition, it is suggested that security training and education be an effective method for discerning cyber-attacks within academia and industries. Despite the importance and the necessity of the training, prior study did not investigate the quantitative utility of security training in an organizational level. Due to the absence of referential studies, many firms are having troubles in making decisions with respect to arranging optimal security training programs with limited security budgets. The main objective of this study is to find out a relationship between cybersecurity training and the number of incidents of organizations. Thus, this study quantified the effectiveness of security training on security incidents as the first study. This research examined the relationship among three main factors; education time, education participants, and outsourcing with numbers of cybersecurity incidents. 7089 firm level data is analyzed through Poisson regression method. Based on analysis results, we found that the negative relationship between security trainings and the occurrence of cybersecurity incidents. This study sheds light on the role of security training and education by suggesting its positive association with reducing the number of incidents in organizations from the quantitative perspective. The result of this study can be used as a referential guide for information security training decision-making procedure in organizations.