Multidimensional augmented current equation including velocityovershoot

The augmented drift-diffusion current equation, which includes velocity overshoot effects through the space derivatives of the electric field, cannot be directly extended beyond one dimension. A new formalism is developed which considers the carrier heating and the distribution relaxation effects to obtain a multidimensional augmented drift diffusion current equation. The equivalent mobility containing the velocity overshoot correction is derived from the perturbation analysis on the carrier temperature using the energy balance equation. The issues related to the numerical implementation of this generalized model and the validity of the assumptions are also discussed     

Biochemical basis for increased susceptibility to Cidofovir of herpes simplex viruses with altered or deficient thymidine kinase activity

It has been observed that herpes simplex virus mutants with deficient or altered thymidine kinase activity are more susceptible to Cidofovir (CDV; 1-[(S)-3-hydroxy-2-(phosphonomethoxy)propyl]cytosine dihydrate) in tissue culture than are the parental strains. During infection of cells, the elevation of the dCTP pool by thymidine kinase mutant viruses is less than that induced by the wild-type virus. The competition between CDV diphosphate and dCTP at the viral polymerase is therefore changed in favor of CDV diphosphate, enhancing its activity.     

Ovarian mucinous cystadenocarcinoma with mural nodules of anaplastic carcinoma: report of a case and review of the literature

A decline of cytosol protein kinase C activity was observed in rat myocardial cells at 4 and 8 h after endotoxin administration, and membrane-associated protein kinase C activity rose at the same time. The activity of membrane protein kinase C in aortic smooth muscle cells at 0.5 and 4 h after endotoxin injection was higher than that in control, while cytosol protein kinase C activity was lower. The results indicate that protein kinase C was activated in myocardial cells and aortic smooth muscle cells during various phases of endotoxemia.     

Transfected glucocorticoid receptor and certain GR fragments evoke cell death in malignant lymphoid, not myeloid cell lines

We compared the data from four growth hormone (GH) immunoassays for analyzing 24-h GH profiles in four apparently normal subjects and four obese subjects (508 serum samples). The detection limit was 0.02 microgram/L for one immunochemiluminometric assay (ICMA), 0.1 microgram/L for two IRMAs, and 0.4 microgram/L for one RIA. All GH pulses with a peak ICMA value > 1 microgram/L were detected by each of the other methods. Overall, the correlation coefficient between the values obtained with all four assays exceeded 0.90. However, for GH concentrations < or = 0.25 microgram/L, acceptable concordance (r2 > or = 0.80) was reached only between the ICMA and one IRMA; between the ICMA and the RIA, concordance was acceptable only for GH concentrations > or = 10 micrograms/L. In the normal subjects, the percentage of undetectable values was 0% with the ICMA but 29% with one of the IRMAs; in obese subjects, the corresponding values were 12% and 38%.     

应用音平化渣图象分析和指导转炉造渣操作

利用音平化渣图象可以清晰地看出在转炉造渣过程中何时发生喷溅，何时发生炉渣返干和何时化渣正常。应用音平化渣图象和炉渣三元相图，可以正确地分析发生喷溅和返干的原因，从而找到避免突发性喷溅和严重返干的方法。正确的枪位和炉渣碱度控制是实现平稳吹炼的保证，而音平化渣图象能帮助操作工实现这一目标。     

Advances in speech transcription at IBM under the DARPA EARS program

This paper describes the technical and system building advances made in IBM's speech recognition technology over the course of the Defense Advanced Research Projects Agency (DARPA) Effective Affordable Reusable Speech-to-Text (EARS) program. At a technical level, these advances include the development of a new form of feature-based minimum phone error training (fMPE), the use of large-scale discriminatively trained full-covariance Gaussian models, the use of septaphone acoustic context in static decoding graphs, and improvements in basic decoding algorithms. At a system building level, the advances include a system architecture based on cross-adaptation and the incorporation of 2100 h of training data in every system component. We present results on English conversational telephony test data from the 2003 and 2004 NIST evaluations. The combination of technical advances and an order of magnitude more training data in 2004 reduced the error rate on the 2003 test set by approximately 21% relative-from 20.4% to 16.1%-over the most accurate system in the 2003 evaluation and produced the most accurate results on the 2004 test sets in every speed category.     

Electrical properties and positron annihilation study of (Ba<Subscript>1−<Emphasis Type="Italic">x</Emphasis></Subscript>Ho<Subscript><Emphasis Type="Italic">x</Emphasis></Subscript>)TiO<Subscript>3</Subscript> ceramics

DC resistivity, dielectric constant, dielectric loss and positron annihilation spectra of (Ba_1−x Ho _x )TiO₃ ceramics have been measured as a function of holmium concentration x. It has been found that the DC resistivity of (Ba_1−x Ho _x )TiO₃ is strongly dependent on the Ho content: it decreases three orders of magnitude and reaches a minimum at x = 0.4%. Doping with 0.6% holmium increases the permittivity of BaTiO₃ by approximately three times (from ∼1,300 to ∼4,000), with only a slight increase in the corresponding dielectric loss. The local electron density and defect concentration estimated using positron annihilation technique conforms well to the features found in the dielectric and resistivity measurements. The results have been discussed in terms of a mixed compensation model.     

Coordinating Agents in Shop Floor Environments From a Dynamic Systems Perspective

In this paper, we address agent coordination from a dynamic systems perspective and propose a dynamic coordination model, which is inspired by biological metabolic systems. A new coordination mechanism through dynamic local adjustment (CDLA) is presented, and coordination is achieved when every agent utilizes explicitly the global system dynamics and performs iteratively a dynamic local adjustment procedure. The CDLA mechanism is investigated in an example multiagent shop floor system. The results show that the example manufacturing process is well-coordinated and the coordination approach is practically applicable and effective     

Adaptive smoothing: a general tool for early vision

A method to smooth a signal while preserving discontinuities is presented. This is achieved by repeatedly convolving the signal with a very small averaging mask weighted by a measure of the signal continuity at each point. Edge detection can be performed after a few iterations, and features extracted from the smoothed signal are correctly localized (hence, no tracking is needed). This last property allows the derivation of a scale-space representation of a signal using the adaptive smoothing parameter k as the scale dimension. The relation of this process to anisotropic diffusion is shown. A scheme to preserve higher-order discontinuities and results on range images is proposed. Different implementations of adaptive smoothing are presented, first on a serial machine, for which a multigrid algorithm is proposed to speed up the smoothing effect, then on a single instruction multiple data (SIMD) parallel machine such as the Connection Machine. Various applications of adaptive smoothing such as edge detection, range image feature extraction, corner detection, and stereo matching are discussed