Faradaic Fenton Pixel: Reactive Oxygen Species Delivery Using Au/Cr Electrochemistry

Reactive oxygen species (ROS) are an integral part of many anticancer therapies. Fenton-like processes involving reactions of peroxides with transition metal ions are a particularly potent and tunable subset of ROS approaches. Precise on-demand dosing of the Fenton reaction is an area of great interest. Herein, we present a concept of an electrochemical faradaic pixel that produces controlled amounts of ROS via a Fenton-like process. The pixel comprises a cathode and anode, where the cathode reduces dissolved oxygen to hydrogen peroxide. The anode is made of chromium, which is electrochemically corroded to yield chromium ions. Peroxide and chromium interact to form a highly oxidizing mixture of hydroxyl radicals and hexavalent Cr ions. After benchmarking the electrochemical properties of this type of device, we demonstrate how it can be used under in vitro conditions with a cancer cell line. The faradaic Fenton pixel is a general and scalable concept that can be used for on-demand delivery of redox-active products for controlling a physiological outcome.     

Effect of Gamma Irradiation on the Electrical Properties of Extruded Bi85Sb15〈Те〉 Samples

Inorganic Materials - The electrical conductivity (σ), thermoelectric power (α), and Hall coefficient (RH) of Bi85Sb15〈Те〉 samples have been measured in the...     

Wurtzite-type ZnS nanoparticles by pulsed electric discharge

The synthesis of wurtzite-type ZnS nanoparticles by an electric discharge submerged in molten sulfur is reported. Using a pulsed plasma between two zinc electrodes of diameter 5 mm in molten sulfur, we have synthesized high-temperature phase (wurtzite-type) ZnS nanocrystals with an average size of about 20 nm. The refined lattice parameters of the synthesized wurtzite-type ZnS nanoparticles were found to be larger than those of the reported ZnS (JCPDS card no 36-1450). Synthesis of ZnMgS (solid solution of ZnS and MgS) was achieved by using ZnMg alloys as both cathode and anode electrodes. UV-visible absorption spectroscopy analysis showed that the absorption peak of the as-prepared ZnS sample (319 nm) displays a blue-shift compared to the bulk ZnS (335 nm). Photoluminescence spectra of the samples revealed peaks at 340, 397, 423, 455 and 471 nm, which were related to excitonic emission and stoichiometric defects.     

Laboratory nuclear-physics methods for determining the characteristics of charged particle silicon detectors

A review is presented of “nontraditional” laboratory nuclear-physical methods for determining key parameters of charged-particle semiconductor detectors, such as the sensitive depth and the energy resolution. The methods for measuring the sensitive depth are based on the peculiarities in interactions of radiation from standard α,β, and γ sources and monochromatic neutrons with the detector materials and require that several “reference” detectors with known characteristics be available. Using the proposed methods, it is possible to preliminarily estimate the serviceability of detectors before employing them in expensive experiments, e.g., on accelerator beams.     

Effect of Gamma Irradiation on the Magnetothermoelectric Properties of Extruded ZrO2-Modified Bi0.85Sb0.15

Inorganic Materials - Electrical and thermal properties of extruded unmodified and ZrO2-modified Bi0.85Sb0.15 samples have been studied as functions of gamma dose at temperatures from ~77 to 300 K...     

Petroleum of the Kaverochkin field

Translated from Khimiya i Tekhnologiya Topliv i Masel, No. 8, pp. 35–36, August, 1989.     

Crude oils of the South Caspian Basin

Translated from Khimiya i Tekhnologiya Topliv i Masel, No. 12, pp. 17–20, December, 1991.     

Onion-like carbon-encapsulated Co,Ni, and Fe magnetic nanoparticles with low cytotoxicity synthesized by a pulsed plasma in a liquid

We synthesized onion-like carbon-encapsulated Co, Ni, and Fe (Co–C, Ni–C, and Fe–C) magnetic nanoparticles with low cytotoxicity using pulsed plasma in a liquid. The pulsed plasma is induced by a low-voltage spark discharge submerged in a dielectric liquid. The face-centered cubic Co and Ni, and body-centered cubic Fe core nanoparticles showed good crystalline structures with an average size between 20 and 30 nm were encapsulated in onion-like carbon coatings with a thickness of 2–10 nm. Vibrating-sample magnetometer measurements revealed the ferromagnetic properties of as-synthesized samples at room temperature (Co–C = 360 Oe, Fe–C = 380 Oe, and Ni–C = 211 Oe). Raman-spectroscopy analysis found onion-like carbon shells composed of well-organized graphitic structures. Thermal gravimetric analysis showed a high stability of the as-synthesized samples under thermal treatment and oxidation. Cytotoxicity measurements showed higher cancer cell viability than samples synthesized by different methods.