Transposition of the tendon of pronator teres in cerebral palsy

We have considered the indications for and results of transplanting pronator teres to extensor carpi radialis brevis in cerebral palsy. The operation has some virtue but a very limited application. We achieved satisfactory functional results in six of nine patients and some improvement in one. Two operations failed because of poor selection. In all patients the appearance of the limb was improved.     

The opposing roles of the Akt and c-Myc signalling pathways in survival from CD95-mediated apoptosis

Expression of the proto-oncogene c-myc stimulates cell proliferation in the presence of the appropriate survival factors and triggers apoptosis in their absence; this dual capacity ensures that cell growth is restricted to the correct paracrine environment and is thereby strictly controlled. Recently our laboratory demonstrated that c-Myc-induced apoptosis requires the CD95 death receptor pathway and that insulin-like growth factor (IGF-1) signalling suppresses this killing. To investigate further the links between c-Myc and IGF-1 pathways in CD95-induced apoptosis, we examined the effects of c-Myc and a downstream IGF-1 survival kinase, Akt, on killing mediated by CD95 and its recruited effector proteins (FADD and caspase-8). Here, we show that c-Myc activation does not exacerbate killing induced by FADD or pro-caspase-8, which narrows the point at which c-Myc exerts its action downstream of the interaction of CD95 with its ligand and upstream of FADD. We show further that activated Akt suppresses CD95-induced apoptosis and that Akt exerts its activity at a point downstream of FADD but upstream of caspase-8. These results restrict the possible mechanisms by which CD95-induced apoptosis is modulated by death signals and survival factors.     

Isolated vagal nerve palsy associated with a dissection of the extracranial internal carotid artery

A 40-year-old man had paralysis of the right vocal cord. Imaging showed a dissection of the extracranial internal carotid artery, and physical examination disclosed paresis of the right side of the soft palate. To our knowledge, this is only the second report of carotid dissection presenting as an isolated vagal neuropathy. Most often, multiple lower cranial nerves are involved. The CT, MR imaging, and MR angiographic findings are presented and the topic is reviewed.     

High temperature oxidation behaviors of Ti-Cr alloys with Laves phase TiCr2

1　ＩＮＴＲＯＤＵＣＴＩＯＮＷｉｔｈａｈｉｇｈｍｅｌｔｉｎｇｔｅｍｐｅｒａｔｕｒｅ ,ｃｈｒｏｍｉｕｍｉｓｔｈｅｓｏｌｅｒｅｆｒａｃｔｏｒｙｍｅｔａｌｅｌｅｍｅｎｔｗｉｔｈｇｏｏｄｈｉｇｈｔｅｍ ｐｅｒａｔｕｒｅｏｘｉｄａｔｉｏｎｒｅｓｉｓｔａｎｃｅ[1] ,ｓｏ     

原位红外技术研究天然橡胶/粘土复合材料热降解产物

将粘土经还原剂及酸处理,再与天然胶乳共沉制备粘土胶复合材料, 用带原位样品池的傅立叶变换红外光谱仪动态研究粘土胶复合材料在不同温度下热降解气相产物。在低分解温度下,粘土胶分解产物主要是乙烯、低分子烯烃类及含羰基化合物;随分解温度升高,则低分子烯烃含量减少,较长链烯类生成,并同时产生大量烷烃类分解产物。随着粘土中Cu,Mn,Co,Fe等金属组分含量升高,粘土胶分解产物中含羰基氧化产物、烯烃及CO₂含量增加,说明金属组分对粘土胶降解氧化产生促进作用。     

辽西地区柏杖子金矿床地质特征

柏杖子岩浆热液型金矿位于翼东－辽西贵金属矿化集中区东部，金矿体赋存于杖子岩体内及外接触带，柏杖子岩体为浅部－超浅成富含成矿元素及挥发份的同熔型花岗岩，成矿物质主要来源于柏杖子岩体，成矿岩石为富碱的酸性侵入岩，近矿围岩蚀变主要为硅化、钾化、绢云母化。     

A receptor subtype involved in neuropeptide-Y-induced food intake

Neuropeptide Y (NPY) is a powerful stimulant of food intake and is proposed to activate a hypothalamic 'feeding' receptor distinct from previously cloned Y-type receptors. This receptor was first suggested to explain a feeding response to NPY and related peptides, including NPY2-36, that differed from their activities at the Y1 receptor. Here we report the expression cloning of a novel Y-type receptor from rat hypothalamus, which we name Y5. The complementary DNA encodes a 456-amino-acid protein with less than 35% overall identity to known Y-type receptors. The messenger RNA is found primarily in the central nervous system, including the paraventricular nucleus of the hypothalamus. The extent to which selected peptides can inhibit adenylate cyclase through the Y5 receptor and stimulate food intake in rats correspond well. Our data support the idea that the Y5 receptor is the postulated 'feeding' receptor, and may provide a new method for the study and treatment of obesity and eating disorders.