Covalent functionalization of zinc oxide nanowires for high sensitivity p-nitrophenol detection in biological systems

High-quality zinc oxide (ZnO) nanowires were synthesized using the atmospheric chemical vapor deposition technique and were appropriately characterized. Subsequently, the nanowire surface was covalently grafted with 1-pyrenebutyric acid (PBA) fluorophore, and surface-sensitive X-ray photoelectron spectroscopy and Fourier transform infrared-attenuated total reflectance spectroscopy were utilized to confirm the functionalization of 1-pyrenebutyric acid on the nanowire surface. Additionally, photoluminescence (PL) measurements were used to evaluate the optical behavior of pristine nanowires. Through fluorescence quenching of 1-pyrenebutyric acid by p-nitrophenol, a detection limit of 28 ppb was estimated. Based on these findings, ZnO nanowires functionalized with 1-pyrenebutyric acid are envisaged as extremely sensitive platforms for the ultra-trace detection of p-nitrophenol in biological systems.     

Direct three dimensional tomography of flames using maximization of entropy technique

Presently, there are numerous applications for non-destructive techniques like emission tomography, laser based methods and particle image velocimetry that are used to study flame characteristics. Reconstruction of the flame intensity field using emission tomography has the advantage over other technologies that it gives accurate results but at the same time requires relatively inexpensive equipment, and therefore, has numerous industrial applications. In the present paper, a new algorithm performing Direct-3D reconstruction using the maximization of entropy (MENT) methodology has been introduced. Through detailed studies using a mathematical object, it has been shown that the Direct-3D algorithm shows significantly reduced errors as compared to 2D slice-by-slice reconstruction algorithms. Secondly, the major features of the proposed algorithm, for e.g., effect of orientation, effect of number of views, and robustness have been discussed. Finally, a few qualitative results from actual flames have been presented using a candle and a gas fired burner, and the results match well with the actual flame geometry and intensity distribution.     

Effect of hydrophilic and hydrophobic polymers on permeation of S-amlodipine besylate through intercalated polymeric transdermal matrix: 3(2) designing,optimization and characterization

Objective: Innovation in material science has made it possible to fabricate a pharmaceutical material of modifiable characteristics and utility, in delivering therapeutics at a sustained/controlled rate. The objective of this study is to design and optimize the controlled release transdermal films of S-Amlodipine besylate by intercalating hydrophilic and hydrophobic polymers.

Methods: 3(2) factorial design and response surface methodology was utilized to prepare formulations by intercalating the varied concentration of polymers(A) and penetration enhancer(B) in solvent. The effect of these independent factors on drug release and flux was investigated to substantiate the ex-vivo, stability and histological findings of the study.

Results: FTIR, DSC revealed the compatibility of drug with polymers; however, the semicrystallinity in drug was observed under PXRD. SEM micrographs showed homogeneous dispersion and entanglement of drug throughout the matrix. Results from the permeation study suggested the significant effect of factors on the ex vivo permeation of drug. It was observed that drug release was found to be increased with an increase in hydrophilic polymer concentration and PE. The formulations having polymers (EC:PVPK-30) at 7:3 showed maximum drug release with highest flux (102.60?±?1.12?µg/cm²/h) and permeability coefficient (32.78?±?1.38?cm/h). Significant effect of PE on lipid and protein framework of the skin was also observed which is responsible for increased permeation. The optimized formulation was found to be stable and showed no-sign of localized reactions, indicating safety and compatibility with the skin.

Conclusion: Thus, results indicated that the prepared intercalated transdermal matrix can be a promising nonoral carrier to deliver effective amounts of drug.     

A new general model for phase-change heat transfer of waxy crude oil during the ambient-induced cooling process

The thermal process during shutdown (a stoppage state of the pipeline), of which the essence is an irregular phase-change process accompanied by natural convection, non-Newtonian behavior, and sometimes turbulence, is a critical problem in crude oil transportation engineering. An accurate calculation of the thermal process during shutdown is more than necessary for the safety of crude oil pipeline; however, it faces some challenges due to the complexity of the phase change. In this study, the phase change of waxy crude oil during the cooling process is divided into four stages, which includes a pure liquid natural convection, solid/liquid dispersion natural convection, coexistence of dispersion system natural convection and porous media natural convection, and pure porous media convection, according to different heat transfer mechanisms on different stages. Based on this division, a general phase-change heat transfer model is proposed for the thermal calculation of waxy crude oil during shutdown. Compared with the previous research, this model appropriately includes the influences of non-Newtonian behavior, phase evolution as well as turbulence. With the proposed model, the temperature drop characteristic of a sample pipeline is analyzed and the influencing factors are investigated.     

Distribution and Prediction of Boundary Shear in Diverging Compound Channels

Measurement of bed shear stress is always a challenging task for engineers. In river engineering, bed shear is a fundamental variable and is important in estimating flow resistance and sediment transport. In this study, experiments are carried out in diverging compound channel with smooth bed (perspex sheet) and rough bed (Gravel) conditions to determine the effect of roughness. The shear velocity is estimated from universal logarithmic law. The effect of geometry and roughness on Von-Karman constant, eddy viscosity coefficient, friction factor is studied. The mass conservation and momentum conservation equations are used to derive apparent shear forces at interface of main channel and floodplain. A genetic algorithm model is developed to predict percentage of shear force (%Sfp) carried by sub-sections. To perform better with less and unseen data K-Fold cross-validation technique is used. The model is compared with available models in literature and it is observed that developed model gave better predictions with low MAPE.

     

Real time object detection and trackingsystem for video surveillance system

Multimedia Tools and Applications - This paper introduces a system capable of real-time video surveillance in low-end edge computing environment by combining object detection tracking algorithm....