Tumor heterogeneity and in vitro chemosensitivity testing in ovarian cancer

OBJECTIVE: Our purpose was to study the heterogeneity of drug response in fresh human ovarian tumors to chemotherapeutic agents in an in vitro chemosensitivity assay. STUDY DESIGN: This assay evaluates total tumor cell kill by measuring the intracellular adenosine triphosphate levels of untreated controls and drug-exposed cells at various doses after culture for 6 days. The surviving fraction is calculated by dividing the treated values with the control values. One hundred tumors were tested against four single drugs (cisplatin, the active metabolite of cytoxan, 4-hydroxyperoxy-cyclophosphamide, Taxol, and carboplatin) and two drug combinations (cisplatin plus 4-hydroxyperoxy-cyclophosphamide; cisplatin plus Taxol). RESULTS: There is great variation in the degree of cell death for single drugs and drug combinations among the 100 tumors tested. CONCLUSION: More effective clinical response to chemotherapy may be achieved in patients with ovarian cancer by selecting the most active drugs for chemotherapy, on the basis of in vitro chemosensitivity test results for individual patients.     

La2（MoO4）3：Eu均-花瓣状微／纳米结构的构筑及其荧光性能

在表面活性剂十二烷基硫酸钠（SDS）的作用下，采用温和的水热方法，成功制备了Eu掺杂的花瓣状L丑2（MoO4）3：Eu纳米微结构。这些形貌新颖的微米绒球的直径约3μm，由厚度30nm左右的纳米片次级结构单元自组装构筑而成，分散性良好，形貌规整、大小均一。通过XRD、SEM、TEM测试技术，研究了形貌的形成机理。由于具有良好的结晶度，这些花瓣状La2（MoO4）3：Eu纳米微结构显示出良好的发光性能。     

冀东油田水平井井身结构优化设计

冀东油田油藏、地层、井网复杂,确定适合冀东油田地层特点的水平井最佳井身结构至关重要,压力系数和相关参数的确定是井身结构优化设计的重要基础.针对冀东油田不同区块复杂地层和油藏特性及井身结构设计中的关键事项,利用三压力剖面预测技术,分析出不同区块的三压力剖面分布情况,根据相关参数的确定原则、方法和冀东油田多年研究和钻井实践,得出了不同区块的3个压力系数分布范围及井身结构设计工程系数范围,为合理确定井身结构提供依据.基于以上设计基础,按照井身结构设计基本原则,利用井身结构设计的具体方法和步骤,设计出了适合冀东油田的最优水平井井身结构.     

雷电冲击电流测试系统研究

目的 研究雷电冲击电流测试系统，方法 用无感电阻网络分流器测量雷电冲击电流，并进测量重复性、线性度试验和阶跃波响应试验。结果与结论 所研制的无感电阻网络分流器符合国家标准GB/T7626.5-1999和国际电工委员会标准IEC61000-4-5的要求，且可用于KV级脉冲大电流的测量和雷电浪涌（冲击）模拟器短路电流的波形校准。     

柴胡皂苷的提取与鉴定

报道了大孔吸附层析分离提取柴胡皂苷的实验研究。结果表明。提取分离柴胡皂苷的最佳工艺是：30％乙醇洗杂质、70％的乙醇洗脱2个糖基或3个糖基的柴胡皂苷。柴胡总皂苷的提取率为1．96％。TLC、HPLC检测2个糖基的皂苷是柴胡皂苷b2，属于结构类型Ⅱ。     

由神木锦界电厂的建设看煤电一体化的优势

根据神木锦界电厂煤电一体化建设的特点,分析了破解我国当前煤电之间争执的途径,并介绍了煤电一体化矿井建设的特点。     

产品图象智能检测技术研究

工业界对图象智能检测技术有着迫切的需要。本文通过对火腿肠产品在线感官质量检测关键性技术的深入研究，证实了该项技术住火腿肠类产品在线感官检测中应用的可行性，文中重点讨论了产品图象智能判别系统的硬软件结构、图象检测判别万法、检测实验数据及实验结果分析。     

Numerical Simulation of Independent Advance of Ore Breaking in the Non-pillar Sublevel Caving Method

The mechanism of stress generation and propagation by detonation loading in five separate independent advance of ore breaking patterns is discussed in the paper. An elastic numerical model was developed using AN- SYS/LS-DYNA 3D Nonlinear Dynamic Finite Element Software. In this package ANSYS is the preprocessor and LS-DYNA is the postprocessor. Numerical models in the paper to actual were l：10 and the element mesh was dissected in scanning mode utilizing the symmetry characteristics of the numerical model. Five different advance rates were studied. Parameters, such as the time required to maximum stress, the action time of the available stress, the maximum velocity of the nodes, the stress penetration time, the magnitude of the stress peak and the time duration for high stress were numerically simulated. The 2.2 m advance appeared optimum from an analysis of the simulation results. The results from numerical simulation have been validated by tests with physical models.     

升平气田产能预测方法

依据升平气田的试井资料，建立了气井产能与压差之间的二次项产能方程。运用此方程可以预测升平气田的单井产能，并且建立了压差平方与kh值相关的气田综合产能方程。当求得气田的平均kh值后，利用该方法可以求得气田的平均产能或生产压差。