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341.
Menshikova Elena Osovetsky Boris Blinov Sergey Belkin Pavel Tomilina Elena Badyanova Irina 《Mine Water and the Environment》2022,41(4):1040-1054
Mine Water and the Environment - Ochre particles in modern alluvium were studied in the area affected by the development of the Kizel coal basin deposits (Perm Krai, Russia) to establish their... 相似文献
342.
A. V. Semencha O. F. Pozdnyakov A. O. Pozdnyakov L. N. Blinov 《Glass Physics and Chemistry》2008,34(1):103-109
Carbon nitride is synthesized in the form of g-C3N4 and β-C3N4 with the use of two methods: (i) thermal decomposition of a mixture of sodium and potassium thiocyanates and (ii) interaction of carbon tetrachloride CCl4 with ammonia NH3. The carbon-nitrogen phases thus synthesized are investigated using electron microscopy, X-ray powder diffraction, IR spectroscopy, and mass spectrometry. 相似文献
343.
Ekaterina Blinova Egor Turovsky Elena Eliseikina Alexandra Igrunkova Elena Semeleva Grigorii Golodnev Rita Termulaeva Olga Vasilkina Sofia Skachilova Yan Mazov Kirill Zhandarov Ekaterina Simakina Konstantin Belanov Saveliy Zalogin Dmitrii Blinov 《International journal of molecular sciences》2022,23(21)
A non-surgical pharmacological approach to control cellular vitality and functionality during ischemic and/or reperfusion-induced phases of strokes remains extremely important. The synthesis of 2-ethyl-6-methyl-3-hydroxypyridinium gammalactone-2,3-dehydro-L-gulonate (3-EA) was performed using a topochemical reaction. The cell-protective effects of 3-EA were studied on a model of glutamate excitotoxicity (GluTox) and glucose-oxygen deprivation (OGD) in a culture of NMRI mice cortical cells. Ca2+ dynamics was studied using fluorescent bioimaging and a Fura-2 probe, cell viability was assessed using cytochemical staining with propidium iodide, and gene expression was assessed by a real-time polymerase chain reaction. The compound anti-ischemic efficacy in vivo was evaluated on a model of irreversible middle cerebral artery (MCA) occlusion in Sprague-Dawley male rats. Brain morphological changes and antioxidant capacity were assessed one week after the pathology onset. The severity of neurological disorder was evaluated dynamically. 3-EA suppressed cortical cell death in a dose-dependent manner under the excitotoxic effect of glutamate and ischemia/reoxygenation. Pre-incubation of cerebral cortex cells with 10–100 µM 3-EA led to significant stagnation in Ca2+ concentration in a cytosol ([Ca2+]i) of neurons and astrocytes suffering GluTox and OGD. Decreasing intracellular Ca2+ and establishing a lower [Ca2+]i baseline inhibited necrotic cell death in an acute experiment. The mechanism of 3-EA cytoprotective action involved changes in the baseline and ischemia/reoxygenation-induced expression of genes encoding anti-apoptotic proteins and proteins of the oxidative status; this led to inhibition of the late irreversible stages of apoptosis. Incubation of brain cortex cells with 3-EA induced an overexpression of the anti-apoptotic genes BCL-2, STAT3, and SOCS3, whereas the expression of genes regulating necrosis and inflammation (TRAIL, MLKL, Cas-1, Cas-3, IL-1β and TNFa) were suppressed. 3-EA 18.0 mg/kg intravenous daily administration for 7 days following MCA occlusion preserved rats’ cortex neuron population, decreased the severity of neurological deficit, and spared antioxidant capacity of damaged tissues. 3-EA demonstrated proven short-term anti-ischemic activity in vivo and in vitro, which can be associated with antioxidant activity and the ability to target necrotic and apoptotic death. The compound may be considered a potential neuroprotective molecule for further pre-clinical investigation. 相似文献
344.
Shahida Anusha Siddiqui Ito Fernando Yuniar Rizky Saraswati Teguh Rahayu Iskandar Azmy Harahap Qifa Yao Andrey Nagdalian Andrey Blinov Mohd Asif Shah 《Comprehensive Reviews in Food Science and Food Safety》2023,22(5):3647-3684
Global food production is anticipated to rise along with the growth of the global population. As a result, creative solutions must be devised to ensure that everyone has access to nutritious, affordable, and safe food. Consequently, including insects in diets has the potential to improve global food and nutrition security. This paper aims to share recent findings by covering edible termites as the main aspect, from their consumption record until consumer acceptance. A total of 53 termite species are reported as edible ones and distributed in 6 biogeographic realms. Generally, termites have a nutrient composition that is suitable for human consumption, and cooked termites are a better dietary choice than their raw counterparts. Besides, increasing customer interest in eating termite-based food can be achieved by making it more palatable and tastier through various cooking processes, that is, boiling, frying, grilling, roasting, smoking, and sun-drying. Moreover, edible termites can also be used as a new source of medication by exhibiting antimicrobial activity. Regarding their advantages, it is strongly encouraged to implement a seminatural rearing system to sustain the supply of edible termites. Overall, this paper makes it evident that termites are an important natural resource for food or medicine. Hence, the long-term objective is to stimulate scientific inquiry into the potential of edible insects as an answer to the problem of global food security. 相似文献