Story creation from heterogeneous data sources

There are numerous applications where there is a need to rapidly infer a story about a given subject from a given set of potentially heterogeneous data sources. In this paper, we formally define a story to be a set of facts about a given subject that satisfies a “story length” constraint. An optimal story is a story that maximizes the value of an objective function measuring the goodness of a story. We present algorithms to extract stories from text and other data sources. We also develop an algorithm to compute an optimal story, as well as three heuristic algorithms to rapidly compute a suboptimal story. We run experiments to show that constructing stories can be efficiently performed and that the stories constructed by these heuristic algorithms are high quality stories. We have built a prototype STORY system based on our model—we briefly describe the prototype as well as one application in this paper.

Trust perceptions of online travel information by different content creators: Some social and legal implications

Consumers are increasingly turning to the online environment to provide information to assist them in making purchase decisions related to travel products. They often rely on travel recommendations from different sources, such as sellers, independent experts and, increasingly, other consumers. A new type of online content, user-generated content (UGC), provides a number of legal and social challenges to providers and users of that content, especially in relation to areas such as defamation, misrepresentation and social embarrassment. This paper reports research that examined the level of trustworthiness of online travel information from these different sources. The study used a survey of Australian travel consumers (n = 12,000) and results support the notion that there are differences in the level of trust for online travel information from different sources. Respondents ‘tended to agree’ that they trusted information provided by travel agents, information from commercial operators and comments made by travellers on third party websites. However, the highest level of trust was afforded to information provided on State government tourism websites. These results suggest that greater trust is placed in online travel comments when they are on a specific travel website than when they are on a more generic social networking website. However, respondents were ‘not sure’ that they trusted comments made by travellers on weblogs and on social networking sites. Some 88% of respondents that had not visited UGC websites (or were unsure if they had) indicated that they thought that UGC would be useful in the future – suggesting that they feel that any concerns they may have in relation to legal and social problems resulting from its use will be resolved.     

Axitinib in Ponatinib-Resistant B-Cell Acute Lymphoblastic Leukemia Harboring a T315L Mutation

Adult acute lymphoblastic leukemia (ALL) with BCR-ABL1 rearrangement (Philadelphia chromosome, Ph) is a hematological aggressive disease with a fatal outcome in more than 50% of cases. Tyrosine kinase inhibitors (TKIs) targeting the activity of BCR-ABL1 protein have improved the prognosis; however, relapses are frequent because of acquired somatic mutations in the BCR-ABL1 kinase domain causing resistance to first, second and third generation TKIs. Axitinib has shown in vitro and ex vivo activity in blocking ABL1; however, clinical trials exploring its efficacy in ALL are missing. Here, we presented a 77-year-old male with a diagnosis of Ph positive ALL resistant to ponatinib and carrying a rare threonine to leucine (T315L) mutation on BCR-ABL1 gene. The patient was treated with axitinib at 5 mg/twice daily as salvage therapy showing an immediate although transient benefit with an overall survival of 9.3 months. Further dose-finding and randomized clinical trials are required to assess the real efficacy of axitinib for adult Ph positive ALL resistant to third generation TKIs.     

Broadening effects in Auger neutralization of 130–430 eV Ar ions at Al surfaces

We present a model for electron emission from Al surfaces by Auger neutralization of 130–430 eV Ar⁺ ions, that includes the singular response of the metal conduction band to the abrupt change of the surface potential caused by electron capture by the incident ion. This effect, previously identified in X-ray studies, produces a broadening that plays a significant role in reproducing the higher energy part of the experimental electron kinetic energy distributions.     

Solar direct irradiance at the ground: A parametric approach

A parametric model, giving the solar direct irradiance at the ground, using as input parameters the precipitable water vapour and the optical thickness of particulate matter is presented. The validity of the parametrization is tested against a spectral model checked during field studies.     

The design of a handheld,location-aware guide for indoor environments

Because of the growing spread of mobile and small devices (like PDAs, mobile phones, etc.), designers and developers of interactive systems have to consider user mobility and the dynamic context of use. In this paper we discuss the design criteria we have defined for developing handheld location-aware systems for indoor environments. We analyse some of the technologies currently available for this purpose and examine how to use them in order to obtain location-dependent information. We report on our experience in designing a location-aware guide for museum visitors and identify possible design criteria for this type of system, which uses automatic detection of a change in environment to trigger the presentation of multi-modal, context-dependent information through a hand-held guide.     

Effects of Nonplastic Fines on the Liquefaction Resistance of Sands

A laboratory parametric study utilizing cyclic triaxial tests was performed to clarify the effects of nonplastic fines on the liquefaction susceptibility of sands. Studies previously published in the literature have reported what appear to be conflicting results as to the effects of silt content on the liquefaction susceptibility of sandy soils. The current study has shown that if the soil structure is composed of silt particles contained within a sand matrix, the resistance to liquefaction of the soil is controlled by the relative density of the soil and is independent of the silt content of the soil. For soils whose structure is composed of sand particles suspended within a silt matrix, the resistance to liquefaction is again controlled by the relative density of the soil, but is lower than for soils with sand-dominated matrices at similar relative densities. In this case, the resistance to liquefaction is essentially independent of the amount and type of sand. These findings suggest the need for further evaluation of the effects of nonplastic fines content upon penetration resistance, and the manner in which this relationship affects the simplified methods currently used in engineering practice to evaluate the liquefaction resistance of silty soils.     

Study on an Aldol Reaction Catalyzed by Ti(IV)/Calix[n]arene Complexes

Ti(IV)/calixarene complexes, formed in situ or previously prepared with standard procedures, can be conveniently used as efficient catalysts in the aldol reaction of Chan's silyloxydiene with a range of aldehydes bearing either activating or deactivating groups, including aromatic, heteroaromatic and α,β‐unsaturated ones. The structure of both calixarene ligand and aldehyde, as well as the reaction conditions, strongly influence the efficiency of the reaction. NMR experiments in conjunction with the experimental results suggest that the structure of the catalytic species in the Ti(IV)/calixarene system prepared in situ is strongly dependent on the concentration and temperature adopted.