The construction and use of nomograms for cerebral blood flow calculation using a 133Xe inhalation technique

Measurement of cerebral blood flow (CBF) using a 133Xe inhalation technique requires monitoring the clearance rate of the radioisotope from the head using externally situated detectors and also from arterial blood using a detector to monitor the expired air activity. The end-tidal concentration function is assumed to be proportional to the arterial concentration function and this has to be deconvoluted from the clearance functions obtained from the head to enable CBF to be calculated. A digital computer is generally considered to be essential for this. In this paper a procedure using three-dimensional nomograms is derived and tested. It is shown that results obtained using the nomograms do not differ significantly from results obtained using a full deconvolution procedure, and so it is not essential to use a computer to calculate CBF by the inhalation technique.     

Hybrid Friction Stir Welding of High-carbon Steel

A high-carbon steel joint,SK5(0.84 wt% C),was successfully welded by friction stir welding(FSW),both without and with a gas torch,in order to control the cooling rate during welding.After welding,the weld zone comprised gray and black regions,corresponding to microstructural variation:a martensite structure and a duplex structure of ferrite and cementite,respectively.The volume fraction of the martensite structure and the Vickers hardness in the welds were decreased with the using of the gas torch,which was related with the lower cooling rate.     

Sequence and tissue distribution of chicken cellular nucleic acid binding protein cDNA

H+,K+-ATPase preparations from pig stomach were modified with a sulfhydryl fluorescence reagent, N-[p-(2-benzimidazolyl)phenyl] maleimide (BIPM). The addition of ATP to the modified enzyme preparations in the presence of Mg2+ decreased the BIPM fluorescence but increased the Trp fluorescence. After exhaustion of ATP, the fluorescence intensities increased and decreased to the original levels, respectively. The results of stopped flow and rapid quenching experiments suggested that the decrease in BIPM fluorescence (36/s) was accompanied by binding of Mg2+ and ATP or phosphorylation (35 36/s) which was followed by slower increases in Trp fluorescence (24/s) and light scattering (20/s). Tosylphenylalanyl chloromethyl ketone-trypsin treatment of the modified preparations, which showed an about 1% decrease in BIPM fluorescence accompanying phosphorylation, gave one major fluorescent peptide peak on reverse-phase chromatography. Amino acid sequence analysis of the peptide revealed the following sequence, Ser-Pro-Glu-X-Thr-His-Glu-Ser-Pro-Leu-Glu-Thr-Arg. On comparison with the amino acid sequence deduced from cDNA from pig stomach [Maeda, M., Ishizaki, J., and Futai, M. (1988) Biochem. Biophys. Res. Commun. 157, 203-209], X was shown to correspond to Cys241 of the alpha-chain in H+,K+-ATPase. These data and others suggest that the decrease in BIPM fluorescence at Cys241 reflects some molecular event triggered by the binding of ATP with Mg2+ and/or phosphorylation, whereas the increases in the intrinsic Trp fluorescence and light scattering reflect one after phosphorylation.     

协同过滤中一种有效的最近邻选择方法

协同过滤中的评分数据稀疏性使得最近邻搜寻不够准确,导致推荐质量较差。基于此,文中提出一种有效的针对稀疏评分的最近邻选择方法--两阶段最近邻选择算法(TPNS)。TPNS分为两个步骤,首先计算用户间的近邻倾向性,选择近邻倾向性较高的用户组成初始近邻集合;然后根据初始近邻集合计算目标用户与其他用户间的等价关系相似性,使用等价关系相似性对目标用户的初始近邻集合进行修正,得到最近邻集合。在MovieLens数据集上对比常用的推荐算法,实验结果表明文中方法在协同过滤推荐的应用中具有更高的准确性。     

GEC架构下RTOS对外接口函数重映射机制

实时操作系统(RTOS)是嵌入式人工智能与物联网终端中重要工具,不同的机构开发的RTOS其实时性、调度规则、任务间通信机制等稍有差异,但基本要素相同.基于通用嵌入式计算机(GEC)架构研究了RTOS在BIOS驻留方法及对外接口函数重映射机制,以NXP的KL36芯片为例给出了mbedOS在BIOS中的驻留实现,并给出对外接口函数重映射实例.实践表明RTOS驻留在BIOS中,不仅缩短了编译链接时间,同时通过对外接口函数的重映射,简化了对RTOS调度机制的理解,降低了编程难度,为有效地实现不同RTOS下应用程序的可移植性提供了技术基础.