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排序方式: 共有885条查询结果,搜索用时 15 毫秒
41.
Behnam Noorani Fatemeh Yazdian Zahra-Soheila Soheili Mehdi Shakibaie Shiva Rahmani 《国际聚合物材料杂志》2018,67(12):754-763
Damage of the retinal pigmented epithelial cells causes various diseases such as age-related macular degeneration in retinal tissue. Nowadays, scientists are attempting to replace lost retinal cells with healthy and efficient cells that provide better conditions for recovering and preventing blindness. In this study, gelatin/chitosan nanofibrous scaffolds with mean diameters of 180?nm were fabricated for subretinal space through electrospinning. Thickness and morphology of the gelatin–chitosan scaffolds were analyzed by scanning electron microscopy (SEM). The results showed that the high rate of degradation, i.e., 90% damage was obtained after 1 month. The cell viability of gelatin/chitosan nanofibers were measured by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. The SEM results of cultured RPE on gelatin/chitosan scaffolds showed the appropriate adhesion of cells on the substrate. The results of the identity of RPE cells cultured on the scaffolds indicated that a large number of cells strongly expressed RPE65 and cytokeratin 8/18. 相似文献
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A novel bilayer nanofibrous wound dressing, with enhanced mechanical properties is successfully fabricated. This membrane, consisted of polyvinylidenefluoride (PVDF) nanofibers for providing tensile strength and polyhydroxybutyrate/chitosan (PHB/CTS) nanofibers loaded with gentamicin with ability of controlled drug delivery, is a great choice for post-surgical ulcers. Mechanical properties showed dramatically improvement of tensile strength by addition of PVDF layer. Gentamycin release represented both an immediate and a sustained release of about 24?h and 1 week, respectively and release increment with increase of CTS ratio. Results also revealed that drug release in structures follow first order kinetic and Fickian release mechanism. 相似文献
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Alireza Hassanzadeh Fatemeh Kanaani Shában Elahi 《Expert systems with applications》2012,39(12):10959-10966
In the era of internet, universities and higher education institutions are increasingly tend to provide e-learning. For suitable planning and more enjoying the benefits of this educational approach, a model for measuring success of e-learning systems is essential. So in this paper, we try to survey and present a model for measuring success of e-learning systems in universities. For this purpose, at first, according to literature review, a conceptual model was designed. Then, based on opinions of 33 experts, and assessing their suggestions, research indicators were finalized. After that, to examine the relationships between components and finalize the proposed model, a case study was done in 5 universities: Amir Kabir University, Tehran University, Shahid Beheshti University, Iran University of Science & Technology and Khaje Nasir Toosi University of Technology. Finally, by analyzing questionnaires completed by 369 instructors, students and alumni, which were e-learning systems user, the final model (MELSS Model1). 相似文献
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Dan A. Buzatu Willie M. Cooper Christine Summage-West John B. Sutherland Anna J. Williams Deborah A. Bass Lisa L. Smith Robert S. Woodruff Jessica M. Christman Steven Reid Randal K. Tucker Christopher J. Haney Ashfaqe Ahmed Fatemeh Rafii Jon G. Wilkes 《Food microbiology》2013
A flow cytometric method (RAPID-B™) with detection sensitivity of one viable cell of Escherichia coli serotype O157:H7 in fresh spinach (Spinacia oleracea) was developed and evaluated. The major impediment to achieving this performance was mistaking autofluorescing spinach particles for tagged target cells. Following a 5 h non-selective enrichment, artificially inoculated samples were photobleached, using phloxine B as a photosensitizer. Samples were centrifuged at high speed to concentrate target cells, then gradient centrifuged to separate them from matrix debris. In external laboratory experiments, RAPID-B and the reference method both correctly detected E. coli O157:H7 at inoculations of ca. 15 cells. In a follow-up study, after 4 cell inoculations of positives and 6 h enrichment, RAPID-B correctly identified 92% of 25 samples. The RAPID-B method limit of detection (LOD) was one cell in 25 g. It proved superior to the reference method (which incorporated real time-PCR, selective enrichment, and culture plating elements) in accuracy and speed. 相似文献
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Various organosilane-treated SiO2 nanoparticles were dispersed in a 2-pack polyurethane coating. The influence of surface modification and silica content on the electrochemical behaviour of the resultant nanocoatings was investigated. Electrochemical impedance spectroscopy (EIS) and open circuit potential (OCP) variations were examined. The surface chemistry of nanoparticles and its effect on the resultant nanocoating morphology were also studied utilising FTIR, and TEM analyses. The results reveal that the presence of more hydrophobic groups and longer-lengthed hydrophobic chains on the surface of nanoparticles, greatly improves the interfacial interactions at the polymer/filler interfaces resulting in a better corrosion performance. 相似文献
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Plasticized poly(vinyl chloride) composites: Influence of different nanofillers as antimigration agents
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In this study, plasticized poly(vinyl chloride) (PVC) composites with different nanofillers, including single‐walled carbon nanotubes (SWCNTs), organoclay, TiO2, and ZnO nanoparticles, were prepared, and their effects on plasticizer migration were investigated. Scanning electron micrographs revealed the dispersion quality of the nanofillers in the polymer matrix. It had a significant influence on the performance of the nanofillers in the process of plasticizer migration. Migration and exudation tests showed that the nanofillers could efficiently hinder plasticizer migration. On the basis of these results, we concluded that carbon nanotubes were the best antimigration agent in the plasticized system. This was ascribed to the high aspect ratio of the SWCNTs and the good interactions between them and the plasticizer. Also, TiO2 nanoparticles showed a better performance compared to the ZnO nanoparticles. This was due to the more homogeneous dispersion of the TiO2 in the polymer matrix and the higher surface area of the particles. The differential scanning calorimetry thermograms were in good agreement with the migration tests. The lowest change in the glass‐transition temperature was observed for the composite filled with SWCNTs. This indicated that a lower amount of the plasticizer migrated from PVC. The thermogravimetric analysis curves showed that the incorporation of the nanofillers improved the thermal stability of the PVC. The results could be useful for determining the efficiency of plasticized PVC in applications. © 2015 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2015 , 132, 42559. 相似文献
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