Neighborhood disadvantage moderates associations of parenting and older sibling problem attitudes and behavior with conduct disorders in African American children.

Data from 296 sibling pairs (mean ages 10 and 13 years), their primary caregivers, and census records were used to test the hypothesis that African American children's likelihood of developing conduct problems associated with harsh parenting, a lack of nurturant-involved parenting, and exposure to an older sibling's deviance-prone attitudes and behavior would be amplified among families residing in disadvantaged neighborhoods. A latent construct representing harsh-inconsistent parenting and low levels of nurturant-involved parenting was positively associated with younger siblings' conduct disorder symptoms, as were older siblings' problematic attitudes and behavior. These associations were strongest among families residing in the most disadvantaged neighborhoods. Future research and prevention programs should focus on the specific neighborhood processes associated with increased vulnerability for behavior problems. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Experimental treatment of brain tumor cells using CD suicide gene

Pro-opiomelanocortin (POMC) is a polyhormone precursor produced predominantly in the pars distalis and pars intermedia of the pituitary gland where it undergoes tissue specific processing to produce a whole array of peptides. We have shown previously that peptides derived from the N-terminal region of POMC are involved in adrenal growth in rats. Using specific two site immunoradiometric assays we have found that the plasma of 17 week old fetal sheep contain a 50 fold excess of pro-gamma-MSH over ACTH. As term approached, the levels of pro-gamma-MSH fell and ACTH rose with evidence of fragmentation of pro-gamma-MSH, suggesting that these peptides act in concert in the development of the fetal adrenal cortex and also provide the necessary drive to bring about parturition. In an attempt to explore the pathophysiology of adrenal function we have cloned human POMC cDNA which led to the discovery of a 9bp addition/deletion mutation in the C-terminus of gamma 3-MSH between positions 67-73. Chinese hamster ovary cells (CHO) cells stably transfected with constructs containing the variant POMC cDNAs have shown a degree of partial processing. Work is currently underway to further investigate the effects of these mutations on the processing by the prohormone converting enzymes PC1 and PC2.     

钢坯修磨金属切除率数学模型的研究

从分析修磨过程运动学和单个磨粒切削入手,建立了磨削深度与磨削过程诸参数(如工艺、材料性能、砂轮性能等)的关系表达式,从而建立起金属切除率与各单项参数的定量关系,为改善或提高修磨效率和修磨过程控制提供了有意义的根据。理论分析与实验结果吻合良好。     

CO2相干激光多普勒测速的研究

叙述运用ＣＷＣＯ２相干激光雷达测量运动目标速度的原理和实验装置，并给出了实验结果，测速精度为０．０１ｍ／ｓ速度分辨率为０．０５ｍ／ｓ，外场实验表明，对于漫射目标，作用距离２００ｍ。     

几种吸附式致冷新工质对的性能预测

应用吸附平衡基本理论对几种可能的吸附式致冷新工质对的性能进行了预测。结果表明，烷烃系列的低混点工质与沸石的配对体系是不可取的，而沸石－氨、活性炭－丙酮、活性炭－氨及活性炭－乙醇则是沸石－水、活性炭－甲醇体系的适宜的替代物。     

专家系统技术在采煤决策及设备选型的应用

专家系统的研究越来越受到人们的重视，它在综合机械化采煤中的应用刚刚起步，文章详细地论述了ＺＪＸＴ系统的知识获取与知识库构造，推理机的特点及系统的功能。     

非数值化产品形位描述模型

传统的形状及位置表示模型通常是建立在低层次的无应用意义的几何拓扑元素之上，因而无法很好地支持计算机辅助设计（ＣＡＤ）向实用化和智能化方向发展。本文提出了一种非数值化的基于约束的产品形位描述模型，并对该模型中存在的一些问题进行了深入的讨论。该模型符合设计人员实际设计思维与过程，同时也支持高层次产品设计信息以及产品的设计过程信息，因而为传统ＣＡＤ系统向新一代实用化智能化ＣＡＤ系统过渡提供了一个良好的产品形位表示模型。     

钛酸酯催化环氧树脂固化动力学研究

用FTIR“原位”技术,研究了钛酸酯(Tc-114)偶联剂对环氧E-44和二氨基二苯基甲烷(DDM)固化反应的催化作用,得出固化程度与时间的关系曲线。又根据DSC曲线,分别算出加有Tc-114和不加Tc-114的两个固化体系的反应表观活化能和反应级数。结果表明,Tc-114的存在使环氧固化反应活化能降低,催化作用明显。     

Silicon doped carbon/Cu joints based on amorphous alloy brazing for first wall application

Amorphous ribbon-type filler-metals represent a promising selection for joining heterogeneous materials together. In this work, rapidly solidified ribbon-type Ti based amorphous filler with a melting temperature of 850 °C and a thickness up to 20 μm is used to join silicon doped carbon to pure copper. SEM examinations demonstrate that a high quality brazed joints could be acquired. The brazed seam has a uniform structure and pore free along its entire length. TiC and ZrC are formed near the interface of carbon and filler-metal when the brazing holds enough time. Using very thin Mo and Cu foil (0.2 mm in thickness) as multiple interlayer are very effective to mitigate the thermal stress occurred in the interface between carbon and copper. The shear strength of this carbon-multiple interlayer-copper joint is more than 20 MPa, and the rupture is mainly occurred on the carbon side.