Prototype personality diagnosis in clinical practice: A viable alternative for DSM–5 and ICD–11.

Several studies suggest that a prototype-matching approach yields diagnoses of comparable validity to the more complex diagnostic algorithms outlined in the Diagnostic and Statistical Manual of Mental Disorders (4th ed.). Furthermore, clinicians prefer prototype diagnosis of personality disorders to the current categorical diagnostic system or alternative dimensional methods. An important extension of this work was to investigate the degree to which clinicians are able to make prototype diagnoses reliably. The aim of this study was to assess the interrater reliability of a prototype-matching approach to personality diagnosis in clinical practice. Using prototypes derived empirically in prior research, outpatient clinicians diagnosed patients' personality after an initial evaluation period. External evaluators independently diagnosed the same patients after watching videotapes of the same clinical hours. Interrater reliability for prototype diagnosis was high, with a median r = .72. Cross-correlations between disorders were low, with a median r = .01. Clinicians and clinically trained independent observers can assess complex personality constellations with high reliability using a simple prototype-matching procedure, even with prototypes that are relatively unfamiliar to them. In light of its demonstrated reliability, efficiency, and versatility, prototype diagnosis appears to be a viable system for the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders and the 11th edition of the International Classification of Diseases, with exceptional utility for research and clinical practice. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

What do people value when they negotiate? Mapping the domain of subjective value in negotiation.

Four studies support the development and validation of a framework for understanding the range of social psychological outcomes valued subjectively as consequences of negotiations. Study 1 inductively elicited and coded elements of subjective value among students, community members, and practitioners, revealing 20 categories that theorists in Study 2 sorted into 4 underlying subconstructs: Feelings About the Instrumental Outcome, Feelings About the Self, Feelings About the Negotiation Process, and Feelings About the Relationship. Study 3 proposed a new Subjective Value Inventory (SVI) and confirmed its 4-factor structure. Study 4 presents convergent, discriminant, and predictive validity data for the SVI. Indeed, subjective value was a better predictor than economic outcomes of future negotiation decisions. Results suggest the SVI is a promising tool to systematize and encourage research on subjective outcomes of negotiation. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Structural brain correlates of verbal and nonverbal fluency measures in Alzheimer's disease.

This study examined the relationships between regional brain volumes and semantic, phonological, and nonverbal fluency in 32 participants with Alzheimer's disease (AD). Object but not animal semantic fluency correlated with frontal and temporal gray matter volumes. Phonological fluency was not significantly associated with any brain volume examined. Nonverbal fluency was selectively associated with bilateral frontal gray matter volumes. Hippocampal volumes, although markedly reduced in these patients, were not related to any of the fluency measures. Results lend evidence to the importance of the frontal lobes in the directed generation of nonverbal and verbal exemplars by AD patients. Furthermore, both left and right-hemisphere regions contribute to the generation of verbal and nonverbal exemplars. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

An empirical study of derivative-free-optimization algorithms for targeted black-box attacks in deep neural networks

Optimization and Engineering - We perform a comprehensive study on the performance of derivative free optimization (DFO) algorithms for the generation of targeted black-box adversarial attacks on...     

Autodetection of ancient Arabian tombs in high-resolution satellite imagery

High circular tombs (HCTs) in southern Arabia provide valuable information for anthropologists who seek fundamental understanding of the transition of ancient peoples from a nomadic pastoral lifestyle, to agro-pastoralism, and eventually to the formation of ancient states. In particular, knowing the geographical distribution of HCTs across the region informs theories on patterns of territoriality and environmental and social factors that are implicated in the emergence of ancient civilizations.

The small size of the HCTs, vast search regions, and rugged terrain make mapping them in the field difficult and costly. In this article, a detection algorithm is described and quantitatively evaluated and establishes the feasibility of automatically detecting these tombs in satellite imagery. By narrowing the search to a smaller set of candidate locations, wide area discovery and mapping can be performed much more effectively.     

A Sterol-Like Odorant in the Urine of Mozambique Tilapia Males Likely Signals Social Dominance to Females

Many species of freshwater fish with relatively simple mating strategies release hormonally derived sex pheromones in urine. However, it is not known whether species with more complex reproductive strategies use specialized urinary chemical signals. We addressed this by using the Mozambique tilapia (Oreochromis mossambicus Peters 1852), a lek-breeding species in which males establish dominance hierarchies and visiting females mate preferentially with territorial/dominant males. We measured urination frequency of territorial males in social isolation and in the presence of females that were either ready to spawn or had finished spawning. In groups of fish, we monitored the volume of urine stored in subordinate and dominant males to determine if urine volume and olfactory potency (by recording electro-olfactograms, EOG, in females) are related to the male’s social rank. Dominant, territorial males stored more urine than subordinates and released it in short pulses, the frequency of which increased in the presence of females ready to spawn but not in the presence of post-spawn females. Urine from subordinate and dominant males was fractionated by liquid chromatography and fractions tested for olfactory potency by using the EOG, with the most potent fraction analyzed by mass spectrometry (MS). The olfactory system of females was sensitive to a urinary compound that was more abundant in the urine of dominant males than in that of subordinates. MS analysis suggested the compound is a sulfated aminosterol-like compound with a formula of C₂₉H₄₀N₂O₁₀S. Therefore, we suggest that dominant/territorial tilapia males dramatically increase urination frequency in the presence of females ready to spawn and that the urinary odorant acts as a pheromonal signal of dominance, thereby influencing female spawning.     

Gas-phase ion association provides increased selectivity and sensitivity for measuring perchlorate by mass spectrometry

Perchlorate (ClO4-) competitively inhibits the uptake of iodide by the thyroid gland. Trace quantities of perchlorate are being increasingly detected in food and environmental samples. There is great concern that perchlorate contamination may be far more widespread than believed until now. Increasingly sensitive and unambiguous methods are needed for measuring perchlorate. We report here an ion chromatography-ion association-electrospray ionization-mass spectrometry (IC/IA-ESI-MS) method of substantially greater selectivity and sensitivity than other available single-stage MS approaches. A long chain dipositive cationic agent (D2+) is added postcolumn in low concentration. This ion associates with perchlorate, even in the gas phase. Perchlorate is, thus, detected as DClO4+ in the positive ion mode at an m/z value between 300 and 400 (depending on the choice of D2+). This results in much better S/N and selectivity, as compared to detecting 35ClO4- at m/z 99, where H34SO4- also responds. We show results for various dicationic agents which vary in their selectivity and affinity for ClO4-, typically being at least 1 order of magnitude more selective for ClO4- over HSO4-. For a 100-microL injected standard, limits of detection (LOD, S/N = 3) are as good as 25 ng/L on a single quadrupole mass spectrometer. Calibration for concentrations up to 100 microg/L displays an r2 value of > or =0.9993. We show applicability to various real samples. A number of the studied reagents are suitable for such applications.     

Stylistic Features, Need for Sensation, and Confirmed Recall of National Smoking Prevention Advertisements

A growing body of research suggests that specific stylistic message features have meaningful implications for message attention, recall, and processing. This study combines content analysis ( n = 45 ads) with population survey data from the Legacy Media Tracking Surveys ( n = 32,977 teens) to (a) identify associations between specific visual, audio, and format features and recall of televised smoking prevention advertisements and (b) test whether these associations are moderated by the need for sensation (NFS). Consistent with research derived from the limited capacity model of mediated message processing, 6 of 7 hypothesized stylistic features increased the likelihood of ad recall. However, contrary to predictions outlined by the activation model of information exposure (AMIE), no differences were observed in the magnitude of these associations by NFS. Results underscore the importance of stylistic considerations in designing health campaign messages and raise questions about the central propositions of the AMIE.