普鲁士蓝加速人体内铯排出效果的观察

本文介绍6例在苏联切尔诺贝利核电站事故期间受到放射性铯内污染的我国驻外人员,在本实验室接受活体测量和服用普鲁士蓝促排的观察结果。6例内污染者分两组分别于受污染后的第114天和第272天开始用药,在大约一个月期间,每人共服药54g(给药方式:每次服1g,每日3次,6天为一个疗程,间隔6天,共用药3个疗程)。观测结果表明,在促排期间,6例内污染者体内铯的生物半排期均明显缩短,~(131)Cs 的生物半排期由对照期(用药前)的54—123d 缩短到28—65d,~(134)Cs 由对照期的42—117d 缩短到23—69d;6例体内放射性铯的累积活度相对于同期未用药条件下的累积活度减少2—21%。     

基于目标检测的SAR图像变化检测方法

SAR图像变化检测有着广阔的应用前景,但目前的方法普遍以精确的配准为前提,使其适用范围受到限制。针对人造目标在SAR图像上的特点,提出了一种基于目标检测的SAR图像变化检测方法。通过图像中的人造目标之间相对位置关系的相似程度确定图像的变化情况,以此来降低对图像配准精度的要求。实验表明该方法在很宽的配准精度范围内都可获得较满意的结果。     

Nitrogen utilization and transformation in red soil fertilized with urea and ryegrass

The influence of fertilization with urea and ryegrass on nitrogen utilization and transformation in red soil has been studied by using ^15N tracer method.When urea and ryegrass were applied alone or in combination,the percentage of N uptaken by ryegrass from labelled urea was 3 and 1.7 times that from labelled ryegrass for the application rate of 200mgN.kg^-1 and 100mgN.kg^-1,respectively;combining application of ryegrass and ureareduced uptake of urea N and increased uptake of ryegrass N by ryegrass plant,but the percentage of N residued in soil increased for urea and decreased for ryegrass.when urea and ryegrass were applied alone,the percentage of N residued in soil from labelled ryegrass was more than 69% while that from labelled urea was less than 25%,and much more ryegrass N was incorporated into humus than urea N.     

电力企业桌面终端安全管理应用研究

阐述电力企业桌面终端安全管理现状,分析电力企业桌面终端普遍存在的问题,梳理电力企业桌面终端的安全管理需求和法规遵循要求,提出“明确桌面终端生产办公设备属性、落实桌面终端安全风险管理”的桌面终端安全管理思想,并在电力企业现有的信息安全管理体系之下,验证在实际应用中实施桌面终端安全基线管理的可行性。     

Optimizing wheel profiles and suspensions for railway vehicles operating on specific lines to reduce wheel wear: a case study

Multibody System Dynamics - The selection of a wheel profile is a topic of great interest as it can affect running performances and wheel wear, which needs to be determined based on the actual...     

Phloroglucinol Derivative Carbomer Hydrogel Accelerates MRSA-Infected Wounds’ Healing

Globally, wound infection is considered to be one of the major healthcare problems, with bacterial infections being the most critical threat, leading to poor and delayed wound healing, and even death. As a superbug, methicillin-resistant Staphylococcus aureus (MRSA) causes a profound hazard to public health safety, prompting us to search for alternative treatment approaches. Herein, the MTT test and Hoechst/propidium iodide (PI) staining demonstrated that PD was slightly less toxic to human fibroblasts including Human keratinocytes (HaCaT) cell line than Silver sulfadiazine (SSD), and Vancomycin (Van). In the MRSA-infected wound model, PD hydrogel (1%, 2.5%) was applied with for 14 days. The wound healing of PD hydrogel groups was superior to the SSD, Van, and control groups. Remarkably, the experimental results showed that PD reduced the number of skin bacteria, reduced inflammation, and upregulated the expression of PCNA (keratinocyte proliferation marker) and CD31 (angiogenesis manufacturer) at the wound site by histology (including hematoxylin–eosin (HE) staining, Masson staining) and immunohistochemistry. Additionally, no toxicity, hemocompatibility or histopathological changes to organs were observed. Altogether, these results suggested the potential of PD hydrogel as a safe, effective, and low toxicity hydrogel for the future clinical treatment of MRSA-infected wounds.     

Melanocortin-5 Receptor: Pharmacology and Its Regulation of Energy Metabolism

As the most recent melanocortin receptor (MCR) identified, melanocortin-5 receptor (MC5R) has unique tissue expression patterns, pharmacological properties, and physiological functions. Different from the other four MCR subtypes, MC5R is widely distributed in both the central nervous system and peripheral tissues and is associated with multiple functions. MC5R in sebaceous and preputial glands regulates lipid production and sexual behavior, respectively. MC5R expressed in immune cells is involved in immunomodulation. Among the five MCRs, MC5R is the predominant subtype expressed in skeletal muscle and white adipose tissue, tissues critical for energy metabolism. Activated MC5R triggers lipid mobilization in adipocytes and glucose uptake in skeletal muscle. Therefore, MC5R is a potential target for treating patients with obesity and diabetes mellitus. Melanocortin-2 receptor accessory proteins can modulate the cell surface expression, dimerization, and pharmacology of MC5R. This minireview summarizes the molecular and pharmacological properties of MC5R and highlights the progress made on MC5R in energy metabolism. We poInt. out knowledge gaps that need to be explored in the future.     

岩石切削过程中破坏机制的离散元分析

利用离散单元方法(DEM)对两种不同属性的花岗石样本模型进行了切割模拟,通过调整不同的切削参数计算并分析了岩石切削过程中的切削力、切削深度、切削比能及切削力倾角的变化规律,从细观上探讨了临界切深对岩石脆性破坏模式和塑性破坏模式及其转变的影响,指出了当切削深度逐渐增大时,破坏模式依次从塑性破坏模式到过渡破坏模式最后转变为脆性破坏模式,同时切削力倾角并不随切削深度变化。将离散单元法分析的结果与实际实验进行了比较,表明该方法是合理的。     

电能计量领域的多功能低功耗设计

电力用户是我国电工仪器仪表最大的用户群体,需求量占整个市场的90%。电能表是我国电工仪表行业中产量最大的产品。本文讨论了电能表的低功耗设计需求以及Maxim 提供的 MAXQ3180低功耗电表设计方案。