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191.
Klauer Karl Christoph; Stahl Christoph; Erdfelder Edgar 《Canadian Metallurgical Quarterly》2007,33(4):680
A complete quantitative account of P. Wason's (1966) abstract selection task is proposed. The account takes the form of a mathematical model. It is assumed that some response patterns are caused by inferential reasoning, whereas other responses reflect cognitive processes that affect each card selection separately and independently of other card selections. The model parameters assess the contributions of different interpretational, inferential, and heuristic factors that jointly determine performance in the selection task. The interpretation of most of the model parameters in terms of these different factors is validated experimentally. This model of the selection task is the first to account for the observed frequencies of all 16 possible response patterns that can arise. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
192.
Simplified moment redistribution procedures based on shakedown have recently been approved by AASHTO LRFD Bridge Design Specifications (AASHTO 2004). These procedures are currently only applicable for homogeneous girders, and thus, the objective of this study is to evaluate whether these procedures can be further applied for hybrid HPS 485W girders. A parametric study is carried out using validated three-dimensional finite-element (FE) analyses to study the inelastic behavior of hybrid HPS 485W girders in negative bending for this purpose. The effective plastic moments obtained from the FE studies are compared with those from the proposed prediction equations, where good correlation is observed. A design example of a three-span slab-on-girder bridge with hybrid HPS 485W girders using both elastic design and the simplified moment redistribution procedures is also presented, where it is shown that the use of moment redistribution procedures results in a negative bending section that is 13% lighter than the corresponding elastic design. 相似文献
193.
The Orientations of Large Aspect‐Ratio Coiled‐Coil Proteins Attached to Gold Nanostructures 下载免费PDF全文
Jae‐Byum Chang Yong Ho Kim Evan Thompson Young Hyun No Nam Hyeong Kim Jose Arrieta Vitor R. Manfrinato Amy E. Keating Karl K. Berggren 《Small (Weinheim an der Bergstrasse, Germany)》2016,12(11):1498-1505
Methods for patterning biomolecules on a substrate at the single molecule level have been studied as a route to sensors with single‐molecular sensitivity or as a way to probe biological phenomena at the single‐molecule level. However, the arrangement and orientation of single biomolecules on substrates has been less investigated. Here, the arrangement and orientation of two rod‐like coiled‐coil proteins, cortexillin and tropomyosin, around patterned gold nanostructures is examined. The high aspect ratio of the coiled coils makes it possible to study their orientations and to pursue a strategy of protein orientation via two‐point attachment. The proteins are anchored to the surfaces using thiol groups, and the number of cysteine residues in tropomyosin is varied to test how this variation affects the structure and arrangement of the surface‐attached proteins. Molecular dynamics studies are used to interpret the observed positional distributions. Based on initial studies of protein attachment to gold post structures, two 31‐nm‐long tropomyosin molecules are aligned between the two sidewalls of a trench with a width of 68 nm. Because the approach presented in this study uses one of twenty natural amino acids, this method provides a convenient way to pattern biomolecules on substrates using standard chemistry. 相似文献
194.
Karl Heinz Kienitz 《控制论与系统》2013,44(6):647-654
Modifications to Zadeh's theory of approximate reasoning are proposed to enhance the theory's ability to produce plausible inference results. The modifications include the introduction of a different implication definition and a certainty qualification for fuzzy propositions. Plausible reasoning is characterized by a set of reasoning patterns of practical significance. This set is then used to validate the overall approximate reasoning method. 相似文献
195.
Structured document storage and refined declarative and navigational access mechanisms in HyperStorM 总被引:2,自引:0,他引:2
Klemens Böhm Karl Aberer Erich J. Neuhold Xiaoya Yang 《The VLDB Journal The International Journal on Very Large Data Bases》1997,6(4):296-311
The combination of SGML and database technology allows to refine both declarative and navigational access mechanisms for
structured document collection: with regard to declarative access, the user can formulate complex information needs without
knowing a query language, the respective document type definition (DTD) or the underlying modelling. Navigational access is
eased by hyperlink-rendition mechanisms going beyond plain link-integrity checking. With our approach, the database-internal
representation of documents is configurable. It allows for an efficient implementation of operations, because DTD knowledge
is not needed for document structure recognition. We show how the number of method invocations and the cost of parsing can
be significantly reduced.
Edited by Y.C. Tay. Received April 22, 1996 / Accepted March 16, 1997 相似文献
196.
This study examined the influences of website design on prospective job seekers. A total of 182 participants accessed and reviewed an online job ad. Afterwards, they rated: (a) the attractiveness of the ad’s formatting, (b) the usability of the website, (c) overall evaluations of the organization’s web appeal, (d) impressions of the organization, and (e) willingness to pursue employment with the hiring organization. Although both the formatting attractiveness and usability of online recruitment materials influenced participants’ inclinations to pursue jobs, formatting was more important than usability. Moreover, impressions of the employer mediated the relationship between satisfaction with the website and willingness to pursue employment with the organization. Overall, this research advances knowledge by applying signaling theory to the web-based recruitment domain and by testing a mediated relationship implied therein. In addition, this is the first study to introduce relative weights analysis to the recruitment literature. 相似文献
197.
v. Schröder Karl Boresch K. Dirr R. Ammon Diemair Griebel Schwaibold G. Mall Felicitas Rolleri Kanitz O. Windhausen K. Felix von Querner W. Ludorff E. Fischbach W. Sutthoff Frey-Wyssling Schormüller A. Pirson J. Großfeld E. Chytrek Koelitz Hans Hawelka W. Schreiber Brüning Estler Pawletta W. Wodsak Jesser H. J. Steinbeck Seuss Schmitz Lars Erlandsen W. Hämmerle Masch A. Bäurle W. Leithe Rudolj Abderhalden Haevecker Fr. Bartschat Garber G. Stamm Gertraude Körner-Hennig G. Steinhoff Johannes Wolf Rob Jungkunz Schönfeld Ed. Rentz Klinc K. Höll 《European Food Research and Technology》1940,79(6):568-608
198.
199.
Confocal scanning laser microscopy (CSLM) was used to study the microcirculation of the brain neocortex in anaesthetized rats. After removal of the dura mater, implantation of a closed cranial window, and intravenous injection of fluorescein, three-dimensional reconstructions of cortical capillaries were performed down to a depth of 250 μm below the pial surface. Using a one-dimensional approach (single line scanning), erythrocyte (negative contrast in fluorescently labelled plasma) and leucocyte (labelled with rhodamine 6 G) velocity and supply rate in cortical capillaries were measured. The effect of CO2-inhalation on capillary blood flow dynamics was studied. Capillaries were imaged continuously for up to 1 h without changes in flow or fluorescence pattern. However, by increasing the laser power 10–100-fold, aggregate formation was induced and capillaries were occluded, possibly due to damage to vascular endothelium. We conclude that CSLM can be used to study morphological and dynamic aspects of fluorescently labelled subsurface structures in organs of experimental animals. 相似文献
200.
Ramona Erber Miriam Angeloni Robert Sthr Michael P. Lux Daniel Ulbrich-Gebauer Enrico Pelz Agnes Bankfalvi Kurt W. Schmid Robert F. H. Walter Martina Vetter Christoph Thomssen Doris Mayr Frederick Klauschen Peter Sinn Karl Sotlar Katharina Stering Albrecht Stenzinger Marius Wunderle Peter A. Fasching Matthias W. Beckmann Oliver Hoffmann Rainer Kimmig Nadia Harbeck Rachel Wuerstlein Fulvia Ferrazzi Arndt Hartmann 《International journal of molecular sciences》2022,23(15)
In intermediate risk hormone receptor (HR) positive, HER2 negative breast cancer (BC), the decision regarding adjuvant chemotherapy might be facilitated by multigene expression tests. In all, 142 intermediate risk BCs were investigated using the PAM50-based multigene expression test Prosigna® in a prospective multicentric study. In 119/142 cases, Prosigna® molecular subtyping was compared with local and two central (C1 and C6) molecular-like subtypes relying on both immunohistochemistry (IHC; HRs, HER2, Ki-67) and IHC + tumor grade (IHC+G) subtyping. According to local IHC, 35.4% were Luminal A-like and 64.6% Luminal B-like subtypes (local IHC+G subtype: 31.9% Luminal A-like; 68.1% Luminal B-like). In contrast to local and C1 subtyping, C6 classified >2/3 of cases as Luminal A-like. Pairwise agreement between Prosigna® subtyping and molecular-like subtypes was fair to moderate depending on molecular-like subtyping method and center. The best agreement was observed between Prosigna® (53.8% Luminal A; 44.5% Luminal B) and C1 surrogate subtyping (Cohen’s kappa = 0.455). Adjuvant chemotherapy was suggested to 44.2% and 88.6% of Prosigna® Luminal A and Luminal B cases, respectively. Out of all Luminal A-like cases (locally IHC/IHC+G subtyping), adjuvant chemotherapy was recommended if Prosigna® testing classified as Prosigna® Luminal A at high / intermediate risk or upgraded to Prosigna® Luminal B. 相似文献