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AIM: The study of the detection rate and potential pathogenetic significance of antibodies to low density oxidated lipoprotein (LDOL) in patients who had ischemic cerebral circulation disorder (ICCD) at young age. MATERIALS AND METHODS: The examination (enzyme immunoassay, general and neurological investigations, laboratory and instrumental tests) covered 148 patients who survived ICCD at young age (mean age 37.2 years). RESULTS: 48 of 108 (44%) patients had LDOL antibodies. Antibodies to cardiolipin, lupus anticoagulant were recorded in 33 (31%) patients. LDOL antibodies were higher and occurred more frequently in patients with Sneddon's syndrome (35% of patients, mean LDOL antibodies-44 units) and primary antiphospholipid syndrome (17% of patients, 45 units) than in atherosclerotic affection of the major head arteries (4%, 29 units) or occlusion of cerebral arteries of unclear genesis (8% of patients, 29 units). CONCLUSION: ICCD were not related to fast development of cerebral atherosclerosis or periaortitis due to production of LDOL antibodies as no relationships were found between their rise and atherosclerotic lesions of cerebral major arteries or periaortitis as shown by ultrasonic dopplerography or cerebral angiography. Feasibility of LDOL antibodies participation in the coagulation cascade and induction of hypercoagulatory condition causing ICCD needs special investigation.  相似文献   
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Translated from Kibernetika i Sistemnyi Analiz, No. 1, pp. 129–145, January–February, 1995.  相似文献   
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The temperature ranges of the structural transformations associated with the transition of a melt into a homogeneous or microhomogeneous state are determined as a result of a comprehensive study of the physical properties of liquid heat-resistant nickel-based alloys. The effect of microalloying on the melt transition temperature is found. A relation between the state of a melt, crystallization, and a structure and the properties of the solid metal is revealed.  相似文献   
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The machinability of the high-nitrogen corrosion-resistant austenitic steel 06Kh22AG15N8M2F during turning is studied. The specific features of the structure of the surface layers in steel workpieces after turning are revealed. The cutting conditions that provide the lowest wear of VK8 alloy cutting tools upon turning are found: the cutting speed is 21–74 m/min, the feed is 0.15–0.60 mm/rev, and the cutting depth is 0.15–0.75 mm. The presence of a large amount of Cr2N-type chromium nitrides in the structure of the steel annealed at 800°C for 2 h and a high nitrogen content in the austenite of the steel quenched from 1100°C increase the wear of the cutting tools. As to turning of the forged steel, the wear resistance of the cutting tools upon turning of the 06Kh22AG15N8M2F steel is higher than that upon turning of 08Kh18N10T steel, in which deformation martensite forms (in surface layers) during turning.  相似文献   
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The structure and corrosion properties of two high-nitrogen 05Kh20AN8MF steels additionally alloyed with 9 and 17% Mn have been studied. Metallographic, X-ray diffraction, and fractographic studies show that both steels have an austenitic structure and high plasticity properties after quenching from 1100 and 1100°C and subsequent aging at 500°C for 2 h. The steel alloyed with 9% Mn and 0.58% V exhibit a higher strength. Both steels have a higher corrosion resistance in a 3.5% NaCl aqueous solution than 12Kh18N9T steel. After aging at 400–600°C, the corrosion rate and the sensitivity to stress corrosion cracking increase.  相似文献   
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