Membrane sterol composition modulates the pore forming activity of syringomycin E in human red blood cells

The syndrome of hypoparathyroidism associated with growth retardation, developmental delay, and dysmorphism (HRD) is a newly described, autosomal recessive, congenital disorder with severe, often fatal consequences. Since the syndrome is very rare, with all parents of affected individuals being consanguineous, it is presumed to be caused by homozygous inheritance of a single recessive mutation from a common ancestor. To localize the HRD gene, we performed a genomewide screen using DNA pooling and homozygosity mapping for apparently unlinked kindreds. Analysis of a panel of 359 highly polymorphic markers revealed linkage to D1S235. The maximum LOD score obtained was 4.11 at a recombination fraction of 0. Analysis of three additional markers-GGAA6F06, D1S2678, and D1S179-in a 2-cM interval around D1S235 resulted in LOD scores >3. Analysis of additional chromosome 1 markers revealed evidence of genetic linkage disequilibrium and place the HRD locus within an approximately 1-cM interval defined by D1S1540 and D1S2678 on chromosome 1q42-43.     

Experimental occlusal interferences. Part IV. Mandibular rotations induced by a pliable interference

In 12 subjects, a pliable, yet unbreakable, intercuspal interference (aluminum shim onlay splint; uniform height of 0.25 mm) was placed between either the right or left maxillary and mandibular second premolars and first molars. During brief and forceful biting (dynamic chewing stroke of about 20 kg force) the interference emulated a semisoft food bolus, and at the end of biting (subsequent static clenching stroke of about 20 kg force) it emulated a rigid metal interference. During dynamic/static biting, rotational electrognathography measured maximum frontal and horizontal plane torque of the right and left mandibular condyles. Eleven subjects (92%) showed frontal plane upward rotation (mean of 1.0 degree) of the condyle contralateral to the interference, and one subject (8%) showed frontal plane upward rotation (0.4 degree) of the condyle ipsilateral to the interference. Two subjects (17%) showed no horizontal plane rotation; seven subjects (58%) showed backward rotation (mean of 0.4 degree) of the condyle contralateral to the interference; and three subjects (25%) showed backward rotation (mean of 0.3 degree) of the condyle ipsilateral to the interference. It is suggested that, in the presence of an occlusal interference, mastication may have both short- and long-term detrimental effects.     

基于状态维修过程中的故障预测问题分析

故障预测作为基于状态维修实现的关键,可以有效支持维修管理者的决策。参照国际标准化组织对故障预测的定义,划分故障预测过程,提出预测方法性能评估至少存在的两种方式,在分类和比较现有预测方法的基础上,明确预测方法的适用范围和限制条件,为工程预测系统的构建提供参考。     

电子引伸计的数字智能化研究

由于目前的电子引伸计精度不高、不快捷、智能化程度不高,对其数字智能化方向的研究十分必要。从数字智能式电子引伸计的特点、关键技术、技术指标及应用入手,制定开发的技术路线,并介绍相应的信号处理技术。     

基于一种混合的节点定位算法的研究

针对基本的DV-Hop节点定位算法会产生不良的节点和多级跳带来的累积误差以及未知节点的坐标没有进行修正等缺点,提出了一种改进的混合节点定位算法WHDV-Hop算法,改进后的算法定位误差率明显比改进前的定位误差率小,通过MATLAB软件对节点定位误差方面进行仿真验证,仿真实验结果证明该改进后的算法稳定、可靠,易于实现。与DV-Hop算法相比,定位精确度提高了4.65%,计算量减少,降低了能量消耗水平,实现预期的目标。     

快速电磁计算软件包设计与应用

描述了快速电磁计算软件包的设计思想,展现了软件包结构和工程计算结果,并且验证了软件包有效性和通用性,也展现了时域积分方程快速算法的优点。     

基于语义识别的不良倾向性信息过滤系统的设计与实现

文章基于自然语言理解和神经网络技术,通过对实际应用的分析,建立了三个领域知识的规则库,设计了一个针对BBS站点的过滤系统原型,实现了对网络上某一特定内容信息的过滤和监控功能,达到了较好的实用效果。     

主从式矿用组合开关通信系统的研究

介绍了3.3kV智能型矿用组合开关控制系统的拓扑结构和各模块工作原理;针对该控制系统对于通信可靠性和实时性的需求,提出了一种基于C8051F040单片机和RS485总线的主从式矿用组合开关通信系统设计方案,详细介绍了该通信系统的硬件设计、通信协议及上下位机之间通信的实现过程。测试结果表明,该通信系统数据传输准确可靠,实时性高。     

基于OpenCv运动目标识别技术的研究

在智能视频监控系统中,快速、准确、有效地检测出运动目标成为人们研究的主要课题之一。本文根据背景差分与帧间差分各自的特点,提出一种基于高斯模型的背景差分与帧间差分相结合的运动目标检测算法。说明高斯背景建模原理以及算法的背景模型更新方法,最后介绍了算法的实现流程和实验结果。在VisualC++6.0环境下,利用计算机视觉类库OpenCV对算法进行了验证。实验结果表明:该算法能快速、有效地提取目标。