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81.
Wireless Personal Communications - In general, Electrocardiogram (ECG) signal gets corrupted by variety of noise at the time of its acquisition. Unfortunately, these noise tend to mask the crucial... 相似文献
82.
Miosz Caban Katarzyna Owczarek Urszula Lewandowska 《International journal of molecular sciences》2022,23(8)
Eye diseases are associated with visual impairment, reduced quality of life, and may even lead to vision loss. The efficacy of available treatment of eye diseases is not satisfactory. The unique environment of the eye related to anatomical and physiological barriers and constraints limits the bioavailability of existing agents. In turn, complex ethiopathogenesis of ocular disorders that used drugs generally are non-disease specific and do not act causally. Therefore, there is a need for the development of a new therapeutic and preventive approach. It seems that matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) have a significant role in the development and progression of eye diseases and could be used in the therapy of these disorders as pharmacological targets. MMPs and TIMPs play an important role in the angiogenesis, epithelial-mesenchymal transition, cell invasion, and migration, which occur in ocular diseases. In this review, we aim to describe the participation of MMPs and TIMPs in the eye diseases, such as age-related macular degeneration, cataract, diabetic retinopathy, dry eye syndrome, glaucoma, and ocular cancers, posterior capsule opacification focusing on potential mechanisms. 相似文献
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84.
The Use of a Novel Ferulic Acid Esterase from Lactobacillus acidophilus K1 for the Release of Phenolic Acids from Brewer's Spent Grain 总被引:1,自引:0,他引:1
Dominik Szwajgier Adam Waśko Zdzisław Targoński Monika Niedźwiadek Monika Bancarzewska 《Journal of the Institute of Brewing》2010,116(3):293-303
In this work, an extracellular ferulic acid esterase was produced in bioreactor cultivations of Lactobacillus acidophilus K1 strain. The enzyme was partially purified using ultrafiltration (10 kDa), dialysis (4–6 kDa) and Fast Protein Liquid Chromatography (Sepharose CM, Sephacryl S‐300). A considerable increment of enzyme activity (31‐fold) in the final preparation was achieved. Two distinct bands (approx. 21.5 kDa and 39 kDa) were obtained after SDS‐PAGE. A high similarity of the purified enzyme (LC‐MS/MS analysis) to tannase and ferulic acid esterase from Burkholderia ambifaria MEX‐5 was obtained. The optimal pH and temperature for the enzyme activity were 6.3 and 37°C, respectively. The enzyme preparation effectively released phenolic acids (mainly ferulic and p‐coumaric acid) from brewer's spent grain. This novel enzyme preparation can be used for the utilisation of a valuable and inexpensive by‐product of the brewing industry. 相似文献
85.
Monika E. Pietrzyk 《Journal of Modern Optics》2013,60(2):303-317
Abstract Properties of a novel configuration of an optical (spatio-temporal) pulse compressor, that is based on a Kerr-type planar waveguide into which two pulses are simultaneously launched, are studied. It is assumed that the pulse which is the subject of the compression propagates in the anomalous dispersion regime, while the auxiliary pulse is in normal dispersion. The best parameters of the proposed compressor are obtained when duration of the auxiliary pulse is so large that this dispersion can be neglected, while energy of the second pulse is above the threshold of first-order soliton generation. It is observed that in such a configuration the compression occurs simultaneously with the generation of a soliton-like solution. It is argued that the proposed configuration with two simultaneously propagating pulses has advantages over the configuration with a single pulse, namely the maximal compression factor and the optimal length of the compressor is, respectively, more than 3 times larger and, at least, 10 times greater than the corresponding values of the compressor with a single pulse. It is also demonstrated that such a compressor can be considered as a universal device, since its operation depends only slightly on the initial parameters of the pulse subject to the compression. 相似文献
86.
Monika Choudhary Jasvinder Kaur Sangha Kiran Grover 《Journal of the American Oil Chemists' Society》2014,91(2):179-206
The Indian dietary pattern has undergone major changes over the past 40 years. Many of these changes involve modification in dietary intake of fats and oils. In developing countries like India, vegetable oils are replacing animal fats because of the cost and health concerns. A wide range of vegetable oils are available in the market but the choice of healthy cooking oil has been a controversial subject since ideas keep on changing as new evidence accumulates. One of the factors holding back the increased use of value-added healthy oils in India is that most potential consumers are genuinely not aware of their health benefits. Edible oil consumption is primarily a community-driven phenomenon in India. The purpose of this paper is to highlight the current scenario of edible oils in India, their composition, health benefits, food applications, stability issues and future aspects as buying the right oil for health has become of great importance. 相似文献
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89.
Fabian Heinemann Meike Gummich Manfred Radmacher Monika Fritz 《Materials science & engineering. C, Materials for biological applications》2011,31(2):99-105
Mineral growth in nacre and other CaCO3-containing biominerals is controlled by biopolymers. Water-soluble proteins were extracted from nacre of the sea snail Haliotis laevigata by dissolving the mineral phase with 6% acetic acid. The influence of this protein mixture on CaCO3 precipitation rates was investigated at different concentrations. A well-established assay for measuring the pH-value during CaCO3 precipitation with and without protein additives was extended by calculating maximum precipitation rates from the pH-values. It could be shown that precipitation rates are greatly influenced by the mixtures of water-soluble nacre proteins. At very low protein concentrations (0.02 μg/ml) a rate enhancement in comparison to the pure supersaturated calcium carbonate solution by a factor of 1.4 was observed. At higher protein concentrations, a strong inhibitory effect occurred, with total inhibition at concentrations of 1.0 μg/ml and higher. Two unspecific proteins (bovine serum albumin and lysozyme) showed little or no modification of precipitation rates. In vivo, the function of the strong inhibition of CaCO3 precipitation by nacre proteins at higher concentrations is presumably to prevent uncontrolled crystallization in the extrapallial fluid. The rate-enhancing capability of proteins at low concentrations may be explained by the presence of acidic and/or hydrophilic moieties. 相似文献
90.
Ann Heylighen Monika Rychtáriková Gerrit Vermeir 《Universal Access in the Information Society》2010,9(3):283-292
Inclusive design aims at objects and environments that are accessible, usable and comfortable for all people throughout their
entire lifespan. In architecture, this aim is usually associated with physical accessibility. Yet acoustic qualities may considerably
impact usability and comfort as well, especially in spaces for listening. This case study explores the notion of acoustic
comfort for all in the context of university education. One auditorium, situated in a historic building and subject to renovation
in the near future, is studied in detail: acoustic obstacles are identified in collaboration with user/experts and are measured
in situ; specific interventions are proposed in consultation with building professionals, technicians and conservation specialists
and are tested using dedicated acoustic simulation software. The study draws attention to the importance of acoustic comfort
for all and offers a first view of which solutions are possible and desirable and how these can be obtained. 相似文献