Capacitances in double-barrier tunneling structures

Capacitances in a double-barrier tunneling structure are calculated for the specific sequential electron tunneling regime. Starting from Luryi's (1988) definition of quantum capacitance, the authors model the charge accumulation in the well during the tunneling process using the Fermi-Dirac distribution. Analytical formulas for the total capacitance and conductance are derived. A complete small-signal model is proposed that demonstrates the external capacitance and conductance of the structure and its frequency behavior. The authors show both theoretically and experimentally that the capacitance in a tunneling structure is both bias- and frequency-dependent     

The pyrophosphate-dependent phosphofructokinase of the protist, Trichomonas vaginalis, and the evolutionary relationships of protist phosphofructokinases

Apoptosis is essential for the precise regulation of cellular homeostasis and development. The role in vivo of Apaf1, a mammalian homolog of C. elegans CED-4, was investigated in gene-targeted Apaf1-/- mice. Apaf1-deficient mice exhibited reduced apoptosis in the brain and striking craniofacial abnormalities with hyperproliferation of neuronal cells. Apaf1-deficient cells were resistant to a variety of apoptotic stimuli, and the processing of Caspases 2, 3, and 8 was impaired. However, both Apaf1-/- thymocytes and activated T lymphocytes were sensitive to Fas-induced killing, showing that Fas-mediated apoptosis in these cells is independent of Apaf1. These data indicate that Apaf1 plays a central role in the common events of mitochondria-dependent apoptosis in most death pathways and that this role is critical for normal development.     

Determination of Si-SiO2 interface recombinationparameters using a gate-controlled point-junction diode underillumination

A novel method is presented to determine Si-SiO₂ interface recombination parameters. The device used is a polysilicon-oxide-semiconductor capacitor with a microscale central junction (a gate-controlled point-junction diode). Data analysis has been performed using a numerical scheme to find a quasi-exact solution for the current combining at the interface. It was found that the interface recombination parameters depend only weakly on trap energy in a wide range around midgap. The cross-section for capturing electrons was found to exceed the cross-section for capturing holes by a factor of 10² to 10³     

A new algebraic white-noise modal combination rule — GAC(A)

It is a well known fact that above the rigid frequency the maximum dynamic modal responses even with different multiple supports can be combined algebraically. Below the rigid frequency, and more specifically in the white-noise (amplified) region of the response spectrum, algebraic modal combination is still a matter of controversy, demonstrated e.g. by the NRC R.G. 1.92 requirement to take the absolute values of the modal responses in heuristic modal combination rules; whereas algebraic support combination is only allowed in conjunction with the envelope support response spectrum (ERS). Such regulatory requirements can lead to unrealistically high calculated responses e.g. in the coupled analysis of light secondary systems attached to heavy primary structures and in the decoupled analysis of systems when the centers of mass and stiffness do not coincide, or when the ERS is used.A new Generalised Algebraic Combination (GAC) methodology has been theoretically developed which allows practical algebraic modal and support combination over the whole frequency range of multiple support spectra. The present paper deals with with the GAC-(A) i.e. the modal combination version in the white noise region of a single response spectrum and more specifically its time history integration validation, which shows that this new modal combination rule can satisfy any realistic conservatism that may be required by regulatory institutions.     

High throughput optical readout of dense arrays of nanomechanical systems for sensing applications

We present an instrument based on the scanning of a laser beam and the measurement of the reflected beam deflection that enables the readout of arrays of nanomechanical systems without limitation in the geometry of the sample, with high sensitivity and a spatial resolution of few micrometers. The measurement of nanoscale deformations on surfaces of cm(2) is performed automatically, with minimal need of user intervention for optical alignment. To exploit the capability of the instrument for high throughput biological and chemical sensing, we have designed and fabricated a two-dimensional array of 128 cantilevers. As a proof of concept, we measure the nanometer-scale bending of the 128 cantilevers, previously coated with a thin gold layer, induced by the adsorption and self-assembly on the gold surface of several self-assembled monolayers. The instrument is able to provide the static and dynamic responses of cantilevers with subnanometer resolution and at a rate of up to ten cantilevers per second. The instrumentation and the fabricated chip enable applications for the analysis of complex biological systems and for artificial olfaction.     

Influence of fermentation methods on neutral detergent fiber degradation parameters

The effect of 3 fermentation methods, in situ (IS) in 4 lactating cows (average pH of 5.8), in vitro (IVn) with media pH of 6.8, or in vitro (IVa) with media pH adjusted to 6.0 using citric acid, on fiber degradation parameters was studied using feeds ground to different particle sizes. Corn silage (CS), grass silage (GS), barley grain (B), sugar beet pulp (BP), and rapeseed cake (RC) were ground using a shear mill. Silages were ground through 8-, 4-, 2-, or 1-mm screens, B and BP through 4-, 2-, or 1-mm screens, and RC through 2- or 1-mm screens. The amylase-treated NDF (aNDF) content of samples ground using a 1-mm screen was 399, 431, 197, 480, and 251 g/kg of DM for CS, GS, B, BP, and RC, respectively, but increased with increasing screen size. Materials were incubated for 0, 6, 12, 24, 48, and 96 h IS, IVn, or IVa. Inoculum for IVn and IVa was prepared as a composite from the cows used for IS. The potentially degradable aNDF (D₀), indegradable aNDF (I), lag time (L), and fractional rate of degradation of potential degradable aNDF (k_d) were estimated using PROC NLIN in SAS. Except for RC, fermentation methods affected most degradation parameters, especially k_d and L. The IVn, IVa, and IS methods resulted in k_d values of 0.291, 0.105, 0.080 h⁻¹ and 0.262, 0.107, 0.103 h⁻¹ for BP and RC, respectively, demonstrating a decreasing rate of degradation for these feeds when fermented under suboptimal pH. In CS, GS, and B, no difference was found in k_d between the IVn and IVa methods, which suggests that differences in pH did not alter k_d in vitro. The k_d values obtained for CS, GS, and B were 0.058, 0.109, 0.168, and 0.028, 0.054, and 0.069 h⁻¹ for the IVn and IS methods, respectively, indicating that the IS method using cows fed at production levels can underestimate the potential rate of NDF degradation. Using the IVa method, L was 12.1, 9.1, 7.8, and 2.5 h for CS, GS, BP, and RC, respectively, which was higher than L obtained from the IVn and IS methods for all feeds except B, where L in all methods were near the parameter boundary of zero hour in NLIN. It was concluded that fermentation methods were more important than grinding screen size on estimates for feed aNDF degradation and that the individual aNDF degradation parameters for the 5 feeds were affected differently by fermentation methods.