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41.
In the present study, the potential of aqueous leaf extract of Nigella arevensis for biosynthesis of silver nanoparticles (AgNPs) was evaluated. The formation of AgNPs was confirmed by color changes and UV–visible spectroscopy, which showed absorbance maxima peak at 416?nm. The transmission electron microscope (TEM) image showed the AgNPs to be anisotropic and mostly spherical with sizes in the range of 5–100?nm. Fourier transform infrared (FTIR) analysis indicated that the flavonoids, alkaloids and phenolic groups present in leaf extract were involved in the reduction and capping of phytogenic AgNPs. These nanoparticles showed the cytotoxic effects against H1229 and MCF-7 cancer cell lines with an IC50 value of 10?μg/mL. AgNPs showed insignificant antioxidant properties compared to the crude extract, and it was effective against clinical isolated bacterial strains. Furthermore, the bioderived AgNPs displayed significant catalytic activity against methylene blue. These results confirmed the advantages and applications of these phytogenic AgNPs using the green method in various fields. 相似文献
42.
Wireless Personal Communications - Benefiting from unlimited power supply, vehicular ad hoc networks (VANETs), in a 5G platform, can deal superiorly with the challenges of providing high... 相似文献
43.
Alejandro J. Paredes Peter E. McKenna Inken K. Ramöller Yara A. Naser Fabiana Volpe-Zanutto Mingshan Li M. T. A. Abbate Li Zhao Chunyang Zhang Juhaina M. Abu-Ershaid Xianbing Dai Ryan F. Donnelly 《Advanced functional materials》2021,31(1):2005792
Poorly soluble drugs constitute more than 60% of currently marketed pharmaceuticals with over two-thirds of promising new chemical entities failing to enter a clinical setting due to solubility issues. Although oral formulations have made some impact, alternative enhancement strategies for administration of such molecules are actively sought. Over the last decade, innovation on a global scale has enabled the expansion of the frontiers of microarray patches (MAPs) further than ever before. Initially designed to load low doses of hydrophilic and potent therapeutic agents, MAPs are now becoming a viable strategy for the immediate and long-acting delivery of poorly soluble drugs through the skin. This together with the advantages of transdermal administration over the oral and parenteral routes, make of MAPs an appealing platform for the development of products with increased patient compliance. Undoubtedly, MAPs will soon become a readily available therapeutic alternative, and experts from academia, industry and regulatory bodies are working together aiming to facilitate the progression of MAPs toward safe and effective clinical use. This review aims to highlight the ability of MAPs to deliver poorly soluble actives, discuss the mechanisms behind in-skin drug absorption, and evaluate the future direction of the field. 相似文献
44.
The safety of hydrogen generation process is a major concern. This paper discusses the quantitative analyzes of the risk imposed on neighborhood from the operation of a hydrogen generator using natural gas reforming process. For this purpose, after hazard identification, the frequency of scenarios was estimated using generic data. Quantitative risk assessment was applied for consequence modeling and risk estimation. The results revealed that, jet fire caused by a full bore rupture in Desulphurization reactor has the highest fatality (26person) and affects the largest area of 5102 m2. The lethality radius, maximum radiation and safe distance of this incident were 140 m, 370 kW/m2 and 225 m respectively. A full bore rupture in Reformer can lead to the most dangerous flash fire. In this incident the concentration of released material in LFL zone (area of 1483.17 m2) and ½ LEL zone (area of 1970.74 m2) were 61,125 ppm and 40,000 ppm respectively. QRA is a credible method to assess the risks of hydrogen generation process. 相似文献
45.
In this paper, the development of a neutron noise simulator for hexagonal-structured reactor cores using both the forward and the adjoint methods is reported. The spatial discretisation of both 2-D 2-group static and dynamic equations is based on a developed box-scheme finite difference method for hexagonal mesh boxes. Using the power iteration method for the static calculations, the 2-group neutron flux and its adjoint with the corresponding eigenvalues are obtained by the developed static simulator. The results are then benchmarked against the well-known CITATION computer code. The dynamic calculations are performed in the frequency domain which leads to discarding of the time discretisation. Then, the developed 2-D 2-group neutron noise simulator calculates both the discretised forward and the adjoint reactor transfer function between a point source and its induced neutron noise, by assuming the neutron noise source as an “absorber of variable strength” type. The neutron noise induced by a “vibrating absorber” type of noise source may also be modeled using the calculated transfer function. The viability of the simulator is verified for different benchmark cases. 相似文献
46.
Mahmoud Moslehi-Fard Naser Alinejad Chapar Rasouli Asghar Sadigzadeh 《Journal of Fusion Energy》2012,31(4):346-351
Toroidal and Poloidal magnetic fields have an important effect on the tokomak topology. Damavand Tokomak is a small size tokomak characterized with k?=?1.2, B t?=?1T, R 0?=?36?cm, maximum plasma current is about 35?KA with a discharge time of 21?ms. In this experimental work, the variation of poloidal magnetic field on the torodial cross section is measured and analyzed. In order to measure the polodial magnetic field, 18 probes were installed on the edge of tokomak plasma with ?θ?=?18°, while a limiter was installed inside the torus. Plasma current, I p, induces a polodial magnetic field, B p, smaller than the torodial magnetic field B t. Magnetic lines B produced as a combination of B t and B p, are localized on the nested toroidal magnetic surfaces. The presence of polodial magnetic field is necessary for particles confinement. Mirnov oscillations are the fluctuations of polodial magnetic field, detected by magnetic probes. Disrupted instability in Tokomak typically starts with mirnov oscillations which appear as fluctuations of polodial magnetic field and is detected by magnetic probes. Minor disruptions inside the plasma can contain principal magnetic islands and their satellites can cause the annihilation of plasma confinement. Production of thin layer of turbulent magnetic field lines cause minor disruption. Magnetic limiter may cause the deformation of symmetric equilibrium configuration and chaotic magnetic islands reveal in plasma occurring in thin region of chaotic field lines close to their separatrix. The width of this chaotic layer in the right side of poloidal profile of Damavand Tokomak is smaller than the width in the left side profile because of Shafranov displacement. Ergodic region in the left side of profile develops a perturbation on the magnetic polodial field lines, B p, that are greater in magnitude than that in the right side, although the values of B p on the left side are smaller than that on the right side of the profile. The Left side of profile is close to the principal magnetic axis and the right side is away from Z axis of Tokamak. 相似文献
47.
Biomass should be considered as one of the promising sources of energy for mitigating greenhouse gas (GHG) emissions. Co-firing biomass with coal has become a solution for meeting the power crisis as well as to reduce the pollutant emissions. The biomass fuels typically found from woody to grassy and solid recovered fuels depending on its origin and properties. It is suggested that co-firing coal with biomass has a substantial effect on SOx and NOx emission level. The ashing process, fly ash quality depends on the conversion technology, capture technology and the properties of the biomass. In order to control the furnace efficiency and production, burnout, optimum injection of biomass sharing with specific information of particle ignition properties are also important. A number of small/laboratory scale and industrial scale experiments have been conducted by different researchers. Different experimental studies performed are reviewed, grouped and summarized based on the fuel processing technology, burnout performance, emission level, environmental aspect, ash information and deposit characteristics, effect of co-firing ratios and adoption of oxy-fuel co-firing. Overall, this paper will highlight existing technologies and emerging trends in co-firing of different types of biomass which will be helpful for future investigations. 相似文献
48.
There is considerable interest in the use of ruthenium as an ultrathin trench liner in damascene copper plating used to fabricate
on-chip interconnects. The problem is that when freshly deposited ruthenium films are exposed to air, their surfaces tend
to undergo spontaneous oxidation, and such deposits (as demonstrated here) are reluctant to undergo reduction. Copper deposition
in an acid plating bath occurs readily on the oxidized ruthenium, but the presence of oxide is known to have a detrimental
effect both on the copper superfilling process and copper adhesion at the Ru/Cu interface. 相似文献
49.
Virgin olive oil (VOO) based polyetheramide (PEtA) was developed from N-N′-bis(2-hydroxyl ethyl) olive fatty amide (HEOA) and orcinol through condensation polymerization. PEtA was further treated with toluylene 2,4-diisocynate (TDI) with different percentages (20–30 wt%) via addition polymerization to obtain poly(ether amide urethane) (PEtAU). The structural elucidation of HEOA, PEtA and PEtAU were carried out by FT-IR, 1H NMR and 13C NMR spectroscopic techniques. Physico-chemical and physico-mechanical properties of the material were investigated by standard methods. Thermal stability and curing behavior of virgin olive oil, HEOA, and PEtAU were assessed by thermogravimetric analysis (TGA), and differential scanning calorimetry (DSC). The corrosion behavior was investigated by potentiodynamic polarization measurements in different corrosive environments (3.5 wt% HCl, 5 wt% NaCl, 3.5 wt% NaOH, tap water) at room temperature. The results showed that UPEtA coatings exhibit good physico-mechanical as well as corrosion resistance performance and can be safely used up to 200 °C. The work is an attempt for alternate utilization of olive oil. 相似文献
50.
M. Zamani M. Taghizadeh M. Naser Moghadasi B. S. Virdee 《Analog Integrated Circuits and Signal Processing》2012,71(1):143-150
In this letter, a 5th-Order single-loop low distortion Sigma–Delta Modulator (SDM) is implemented with the combination of
the comparator-based switched-capacitor (CBSC)-based and op-amp-based techniques for asymmetric digital subscriber line (ADSL)
applications. This structure, which uses integrator (CBSC-based) and IIR filter (op-amp-based) concurrently, has relatively
fewer feed-forward paths and modulator coefficients for sensitivity reduction to mismatch. To lower the power consumption
of the modulator, the integrators are implemented with CBSC, the IIR filter block is implemented by single OTA, and a passive
adder is used to realize the adder at the input of the 5-bit quantizer. The design purpose is minimizing the power consumption
while the dynamic performance maintains high. As shown in the simulation result, for a 2-MHz signal bandwidth, the modulator
achieves a dynamic range (DR) of 86.5 dB and a peak signal-to-noise and distortion ratio (SNDR) of 85 dB with an oversampling
ratio of 8. In addition it consumes 18.75 mW from a 1.8-V power supply at 32 MS/s, which obtains a figure of merit of 1.6e−3. 相似文献