A new hyperbolic shear deformation theory for buckling and vibration of functionally graded sandwich plate

A new hyperbolic shear deformation theory taking into account transverse shear deformation effects is presented for the buckling and free vibration analysis of thick functionally graded sandwich plates. Unlike any other theory, the theory presented gives rise to only four governing equations. Number of unknown functions involved is only four, as against five in case of simple shear deformation theories of Mindlin and Reissner (first shear deformation theory). The plate properties are assumed to be varied through the thickness following a simple power law distribution in terms of volume fraction of material constituents. The theory presented is variationally consistent, does not require shear correction factor, and gives rise to transverse shear stress variation such that the transverse shear stresses vary parabolically across the thickness satisfying shear stress free surface conditions. Equations of motion are derived from Hamilton's principle. The closed-form solutions of functionally graded sandwich plates are obtained using the Navier solution. The results obtained for plate with various thickness ratios using the theory are not only substantially more accurate than those obtained using the classical plate theory, but are almost comparable to those obtained using higher order theories with more number of unknown functions.     

Variation of Fructooligosaccharides and their Metabolizing Enzymes in Onion Bulb (Allium cepa L. cv. Tenshin) During Long-term Storage

ABSTRACT: The objective of this study was to assess the status of fructooligosaccharides (FOS) in onion bulbs ( Allium cepa L. cv. Tenshin) and their metabolizing-enzymes—1-fructoexohydrolase (1-FEH), 1-kestose hydrolyzing enzyme (1-KH), fructan:fructan 1^F-fructosyltransferase (1-FFT) and fructan:fructan 6^G-fructosyltransferase (6G-FFT)—during storage at 15°C. Fructose varies slightly, whereas 1-kestose peaked after 6 wk and then decreased progressively during the last 18 wk of storage. Lower degree of polymerization (DP) 3 to 6) FOS, higher (DP 7 to 12) FOS, total FOS, and total carbohydrates showed similar and close patterns during 24 wk. They varied slightly at the beginning of the storage period; afterward they decreased progressively and regularly during the last 20 wk of storage. 1-FEH and 1-KH activities were low but peaked abruptly after 12 and 16 wk, respectively, after which they decreased to levels higher (1-FEH) or similar (1-KH) to those observed at the beginning of the storage. Surprisingly, 1-FFT activity showed similar pattern to the variation of 1-KH hydrolyzing activity; on the other hand, 6G-FFT, although higher, was stable during 16 wk but decreased after that. The results allowed us to associate FOS to the dormancy and sprouting states, and the peaks of the degrading enzymes were shown to signal the release of dormancy of onion bulb.     

Characterization of the Absorption of Theophylline From Immediate- and Controlled-Release Dosage Forms With a Numerical Approach Using the In Vitro Dissolution-Permeation Process Using Caco-2 Cells

After oral administration, drug absorption rate is recognized to be dependent on two major factors: dissolution and intestinal cells permeability. Caco-2 monolayer cells have been largely used as a permeation study model. In this study, a numerical approach funded on an exponential first-order time relationship was tested to compare immediate- and controlled-release tablets of theophylline using a dissolution-permeation system. The dissolution performance using USP II paddle apparatus was coupled to the permeability studies investigated in Caco-2 cell monolayers. The dissolved samples were taken at different times; their pH and osmolarity were adjusted to render them suitable to Caco-2 permeability studies (osmolarity = 300 mosm, pH = 7.4). The experimental data show that the dissolution fits the exponential first-order relationship rate. The permeability values were in a range of 4.45 10^- 6-5.28 10^- 6 cm/s, and percentages of absorbed drug dose were dependent on the fraction initially present in the donor compartment, indicating that absorption of theophylline was dissolution rate limited. Plotting experimental absorbed fractions (F_a) against experimental dissolved fractions (F_d) show that permeation is the rate-limiting step in drug absorption process in the extended release form of theophylline. Our results demonstrate a general agreement between observed F_a/F_d relationships and theoretical F_a/F_d relationships obtained with our approach funded on dissolution and permeation behavior. We concluded that the couple dissolution-caco-2 system could be a useful tool to characterize intestinal permeation for a new formulation of a drug compared with the conventional one.     

Fuzzy identification in fuzzy databases: The nuanced relational division

In the present article we review the main research works in fuzzy databases; propose an extension of relation division operator to fuzzy databases; provide a model for fuzzy information and resolve the identification problem in fuzzy databases. For this, three notions are relevant: (a) the concept of nuanced information for representing fuzzy values and the associated nuance, (b) the nuanced division operator, (c) the possibility of weighting attributes in order to express data and query pertinence and trust. We then show how to resolve the problem of fuzzy identification with the nuanced division operator. © 1994 John Wiley & Sons, Inc.     

只用一根线驱动LCD的微控制器

HD44780LCD是嵌入系统中最常见的字母显示器。它唯一的缺点是在4bit模式下要使用6个I/O脚．而在8bit模式下要用多达11个I／O脚。以前的设计实例中曾描述过很多节省或扩展I／O脚的方法（参考文献1、参考文献2、参考文献3）。在驱动一个HD44780兼容LCD时．最好使用基线微控制器,而不是逻辑芯片,因为微控制器成本较低．占用电路板空间较小,并且有编程特性。Microchip推出了最小的PIC10F系列微控制器．都采用6脚SOT-23封装。     

Polystyrene latex particles bearing primary amine groups via soap‐free emulsion polymerization

Polystyrene latexes were prepared in the presence of an amino‐containing functional comonomer, N‐(3‐aminopropyl)methacrylamide hydrochloride (APMH), via soap‐free batch emulsion polymerization initiated by the cationic initiator 2,2′‐azobis(2‐amidinopropane) dihydrochloride. These latexes were characterized by studying the influence of the ionic comonomers on the polymerization kinetics, particle size, surface charge density and colloidal properties. The synthesized latexes were monodisperse with a final size between 100 and 600 nm depending on the APMH concentration. The initial polymerization rate and the particle number increased in accordance with the Smith–Ewart theory for soap‐free styrene emulsion polymerization with a hydrophilic functional comonomer. The final functionalization rate of the particles has been particularly studied with the intention of fitting the prepared latexes to be used in the immobilization of biological molecules for biological sample preparation and diagnostic applications. © 2020 Society of Chemical Industry     

Potato Glycoalkaloids: occurrence,biological activities and extraction for biovalorisation – a review

Potato tuber (Solanum tuberosum L.) is the fourth most important agricultural product after wheat, rice and maize. With a total production of 388 million in 2017, c.a. 70% of this total production is processed in developed countries, producing a large amount of potato peel waste (PPW) as by-product. Although PPW is considered as a zero-value by-product by the feed industry because it is too fibrous, for other recycling industries it is an inexpensive by-product due to its significant contents of some interesting nutrients particularly polyphenols and glycoalkaloids. In potato, and Solanum species in general, many glycoalkaloids, predominantly α-chaconine and α-solanine, have been chemically and structurally identified. However, further research is needed to expand the knowledge of the biological values of potato glycoalkaloids in order to develop a recycling process to extract these technologically and nutritionally interesting bioactive ingredients for different sectors, in particular, the agricultural, food and pharmaceutical ones, which are demanding natural, safe and eco-friendly ingredients.     

Anomalous behavior detection-based approach for authenticating smart home system users

International Journal of Information Security - This paper presents Duenna, an authentication framework for smart home systems (SHSs). When using controlling apps (e.g., a smartphone app), Duenna...     

ECRP: an energy-aware cluster-based routing protocol for wireless sensor networks

Energy conservation is the main issue in wireless sensor networks. Many existing clustering protocols have been proposed to balance the energy consumption and maximize the battery lifetime of sensor nodes. However, these protocols suffer from the excessive overhead due to repetitive clustering resulting in high-energy consumption. In this paper, we propose energy-aware cluster-based routing protocol (ECRP) in which not only the cluster head (CH) role rotates based on energy around all cluster members until the end of network functioning to avoid frequent re-clustering, but also it can adapt the network topology change. Further, ECRP introduces a multi-hop routing algorithm so that the energy consumption is minimized and balanced. As well, a fault-tolerant mechanism is proposed to cope up with the failure of CHs and relay nodes. We perform extensive simulations on the proposed protocol using different network scenarios. The simulation results demonstrate the superiority of ECRP compared with recent and relevant existing protocols in terms of main performance metrics.