Amplification of c-myc proto-oncogene in primary tumors, metastases and blood leukocytes of patients with ovarian cancer

The structure of DNA sequences homologous to the viral myc oncogene from ovarian tumours, intact tissues and the same patients peripheral blood leukocytes has been studied. The Southern blot analysis of malignant tumour DNA reveals amplification of c-myc protooncogene of 3 from 11 patients. Metastases DNAs of two from those patients also contain multiple copies of c-myc. No myc gene amplification has been detected in 6 examined benign ovarian tumours. The presence of extra copies of myc-related sequences has been shown in two from three DNA samples from peripheral blood leukocytes of patients with ovarian cancer.     

Relating blow moldability to large amplitude oscillatory shear behavior

The large amplitude oscillatory shear test has been used to discriminate subtle differences in nonlinear viscoelasticity between two high density polyethyene blow molding resins with different processability. Structural network theory was used to explain the subtle differences in terms of entanglement kinetics with remarkable accuracy. The resin with better shape retention characteristics in programmed parison blow molding was found to have a higher kinetic rate constant for molecular re-entanglement.     

Determination of the residual life of welded metal structures

Translated from Fiziko-Khimicheskaya Mekhanika Materialov, No. 3, pp. 111–112, May–June, 1992.     

Apparatus for the automatic measurement of low-frequency acoustical parameters of anisotropic liquids

A measurement and computing system designed for acoustical investigations of liquid crystals, magnetic fluids, etc., in the frequency range 0.15–1.2 MHz is described.Translated from Izmeritel'naya Tekhnika, No. 2, pp. 51–53, February, 1994.     

Perspective channel-type reactor with enhanced safety

Following the search for new design solutions to develop within the framework of channel trends the reactor with enhanced safety the Research and Development Institute of Power Engineering has developed the design of the multiloop boiling water reactor (MKER). The MKER enhanced safety is attained when involving the inherent safety features, passive safety systems as well as the accident consequences confinement devices. The design realizes several advantages which are typical of the channel-type reactors, namely: the design desintegration simplifying the manufacture, control, equipment delivery and decreasing, versus the pressure vessel reactors, the accident effect if it proceeds in an explosive manner; small operating reactivity margin and fuel burnup increased due to continuous refuelling; fuel cycle flexibility allowing comparatively easily to adopt the reactor to the conjuncture of the country fuel balance; multiloop circuit of the main coolant which reduces the degree and effect of the accidents connected with the equipment and pipings rupture; monitoring of the channels and fuel assemblies leak-tightness.     

Measurement of interfacial area concentration in subcooled liquid-vapour flow

In two-fluid modelling, accurate prediction of the interfacial transport of mass, momentum and energy is required. Experiments were carried out to obtain a database for the development of interfacial transport models, or correlations, for subcooled water-steam flow in vertical conduits. The experimental data of interest included the interfacial area concentration, interfacial condensation heat transfer and bubble relative velocity. This paper focuses on the interfacial area concentration. The interfacial area concentration was obtained by measuring the distributions of bubble volume and surface area as well as the area-averaged void fraction at various axial locations in subcooled water-steam condensing vertical upward flow under low flow rate and low pressure conditions. The bubble size and surface area were determined using high-speed photography and digital image processing techniques. The area-averaged void fraction was measured by a single-beam gamma densitometer. The results were compared with existing correlations, which were developed on the basis of data obtained for air-water adiabatic flows. Poor agreement between the present data and the existing correlations was obtained. Accordingly, new correlations suitable for subcooled liquid-vapour bubbly flow are proposed.     

A test piece for mechanical testing of fiber composite materials

This article describes a test piece that minimizes the spread of the results of testing of composite materials on a metal base by extension in the direction of a reinforcing fiber and, from the results, determines the mechanical properties of intermediate and finished products made of these materials.Translated from Izmeritel'naya Tekhnika, No. 10, pp. 39–40, October, 1993.     

Modeling of silicon diffusion in gallium arsenide

A model is developed and a study is performed for amphoteric diffusion of silicon in gallium arsenide. A comparison of predictions with experimental data indicated adequacy of the devised model and high efficiency of the numerical method for solving the diffusion equation.Belorussian State University, Minsk. Minsk Radio Engineering Institute. Translated from Inzhenerno-Fizicheskii Zhurnal, Vol. 65, No. 5, pp. 567–572, November, 1993.