Phloroglucinol Derivative Carbomer Hydrogel Accelerates MRSA-Infected Wounds’ Healing

Globally, wound infection is considered to be one of the major healthcare problems, with bacterial infections being the most critical threat, leading to poor and delayed wound healing, and even death. As a superbug, methicillin-resistant Staphylococcus aureus (MRSA) causes a profound hazard to public health safety, prompting us to search for alternative treatment approaches. Herein, the MTT test and Hoechst/propidium iodide (PI) staining demonstrated that PD was slightly less toxic to human fibroblasts including Human keratinocytes (HaCaT) cell line than Silver sulfadiazine (SSD), and Vancomycin (Van). In the MRSA-infected wound model, PD hydrogel (1%, 2.5%) was applied with for 14 days. The wound healing of PD hydrogel groups was superior to the SSD, Van, and control groups. Remarkably, the experimental results showed that PD reduced the number of skin bacteria, reduced inflammation, and upregulated the expression of PCNA (keratinocyte proliferation marker) and CD31 (angiogenesis manufacturer) at the wound site by histology (including hematoxylin–eosin (HE) staining, Masson staining) and immunohistochemistry. Additionally, no toxicity, hemocompatibility or histopathological changes to organs were observed. Altogether, these results suggested the potential of PD hydrogel as a safe, effective, and low toxicity hydrogel for the future clinical treatment of MRSA-infected wounds.     

丙烯酸酯类反应性微凝胶的制备及其对环氧树脂的增韧作用

采用自稳定分散聚合法,制备了粒径在20nm左右、粒径分布均匀的球形丙烯酸酯类反应性微凝胶;同时研究了其对环氧树脂/间苯二胺(MPDA)体系的增韧效果.结果表明,所制备的丙烯酸酯类反应性微凝胶在室温下呈橡胶态;它是环氧树脂/MPDA体系的一种有效增韧荆,增韧效果受其用量、官能团种类及用量的影响;含有环氧基团的微凝胶颗粒,增韧效果最好,而且提高了环氧树脂的热性能:带有环氧基团的微凝胶颗粒用量越大,或丙烯酸酯类微凝胶中环氧基团的摩尔分数越高,对环氧树脂的增韧效果越好.     

β-PP/PA 6合金的结晶与熔融行为

为了研究β-成核剂在合金中分散对聚丙烯（PP）成核效率的影响,采用2种方法制备了负载型β-成核剂成核PP（β-PP）／聚酰胺6（PA6）合金。用差示扫描量热仪和广角X射线衍射仪研究了不同制备方法及熔融温度对β-PP／PA6合金的结晶行为、熔融特性和β-PP含量的影响。结果表明：PP,PA6先熔融再降温至／90℃加入成核剂制备β-PP,PA6合金的β-PP含量高于先制备β-PP再与PA6混炼制备的合金。熔融温度高有利于β-PP／PA6合金中PP形成β-PP。     

Impact stabilizing controller for hydraulic actuators with friction: Theory and experiments

Stabilizing manipulators during the transition from free to constraint motion is an important issue in contact task control design. This paper documents the development, theoretical analysis and experimental evaluation of a Lyapunov-based control scheme to regulate the impacts of a hydraulic actuator that comes in contact with a nonmoving environment. Upon sensing a nonzero force, the controller positions the actuator at the location where the force was first sensed, exerting minimal force on the environment. The scheme does not require continuous measurement of force or velocity during the short period of impacts, making it very useful for practical cases. Furthermore, no knowledge of the impact dynamics, friction effects, servovalve dynamics, or hydraulic parameters is required for control action. Stability of the control scheme is verified via analytical analyses. Due to the discontinuous friction model and the discontinuous nature of the proposed control law, the control system is nonsmooth. The existence, continuation and uniqueness of Filippov's solution to the system are, therefore, investigated. The extension of LaSalle's invariance principle to nonsmooth systems is next employed to prove that all the solution trajectories converge to the equilibria. The controller is finally tested experimentally to verify its practicality and effectiveness in collisions with hard and soft environments and with various approach velocities.     

基于小波变换和LSTM模型的城市天然气负荷预测

城市燃气公司为防止出现储气量过剩或不足等问题,必须要对天然气负荷量进行预测.对此,提出一种基于小波变换和长短期记忆网络的深度学习模型(wavelet_LSTM),对未来一年的天然气日负荷量进行预测.在某市燃气公司真实数据集上的实验结果表明,该模型有较高的准确性,可以较好地满足城市燃气公司的业务需求.     

基于DSP的视频监控系统的优化仿真设计

设计了基于TMS320C6205DSP的MPEG-4数字视频监控系统,针对软硬件特性对优化方法做了详细阐述并完成了对该系统的仿真优化,最后给出了关键的测试结果。     

一种基于C/S模式的TCP通信程序在Vxworks中设计与实现

结合嵌入式实时操作系统VxWorks实现某测控系统的实际应用,以其中的TCP通信为例,讨论了在VxWorks下实现C/S通信的关键技术。     

Extracting the optimal dimensionality for local tensor discriminant analysis

Supervised dimensionality reduction with tensor representation has attracted great interest in recent years. It has been successfully applied to problems with tensor data, such as image and video recognition tasks. However, in the tensor-based methods, how to select the suitable dimensions is a very important problem. Since the number of possible dimension combinations exponentially increases with respect to the order of tensor, manually selecting the suitable dimensions becomes an impossible task in the case of high-order tensor. In this paper, we aim at solving this important problem and propose an algorithm to extract the optimal dimensionality for local tensor discriminant analysis. Experimental results on a toy example and real-world data validate the effectiveness of the proposed method.     

一致持久的带外虚拟化系统

存储虚拟化能够全面提升存储区域网络的服务质量,而带外虚拟化与带内虚拟化相比具有性能高和扩展性好等优点．提出了运用按序操作、REDO日志以及日志完整性鉴别,共同保证带外虚拟化跨越系统崩溃或断电事故后仍旧可用;设计了一种基于关系模型的磁盘上虚拟化元数据组织方式,它具有可读性好和容易修改的优点;给出了通过分析磁盘分区表兼容典型遗留存储系统的有效方法,它具有庞大遗留系统零切割时间的特点．基于上述关键技术实现的原型系统,在典型实验中表现了很好的性能．