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21.
We are encountering tremendous opportunities and challenges in combining emerging nanotechnology for developing nanoelectronic devices. Researchers are designing nanoelectronic circuits based on newly discovered nanoscale building blocks, such as spintronic devices. In this paper, we calculate conductance in spintronic gates using the nonequilibrium Green's function and show useful operations for "multiterminal" logic gates. These spintronic devices can be used to design complicated spin circuits 相似文献
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23.
Kuo-Ming Chao Muhammad Younas Nick Godwin Pen-Choug Sun 《International Journal of Wireless Information Networks》2006,13(2):141-150
The popularity of grid services has widened their application to numerous domains and increased the utilization of computational resources. In order to create more incentives for the resources owners to lease their resources and prevent users from wasting the resources, the introduction of a market-oriented grid is inevitable. However, the issues for the negotiation between service provider and consumer over the supply and demand of resources can be complex, with highly interdependent issues. In this research, a simulated automated negotiation mechanism including a co-evolutionary mechanism and a modified game theory approach is proposed, to assist them in reaching an agreement over the conflicting issues. In the proposed architecture, the co-evolution process is able to reduce the multiple dimensional search space into a two-dimension search space and identify the appropriate negotiation strategies for the negotiating agents to form a payoff matrix which can be used for the game theory related stage of their interaction. The multiple stage negotiation process is introduced to improve the negotiation result. In this paper, an application which requires a large amount of computational resources to process the data generated from mobile devises is used to demonstrate that the proposed system is able to resolve the conflicts and obtain a valid solution. 相似文献
24.
As the design trend of modern cellular phones evolves to be miniaturization and versatile sound in quality, the electro-mechanical components including the micro-speaker are essential toward size reduction and broad frequency range of sound. To reduce size, a diaphragm type micro-speaker is commonly employed in industry, while to broaden the sound frequency range corrugations on the diaphragm are adopted. The corrugations are generally capable of leading to fairly flat response over a broad range since diaphragm stiffness is decreased in axial direction. To confirm the aforementioned capability, the modeling on a corrugated diaphragm is performed first using finite element method (FEM) to obtain the associated dynamic equations in terms of modal coordinates; then the equations are next combined with the magneto-electrical model of the voice coil motor (VCM) that is attached to the bottom side of the diaphragm. Finally, the acoustic effects of the air inertia on the diaphragm and vents of the outer case are modeled using basic acoustic theories. Assembling all derived system equations and solving them, the frequency response of the micro-speaker in sound pressure level (SPL) can be simulated. It shows that the diaphragm corrugation in fact helps flatten the SPL response of the micro-speaker (especially in high frequency range) to lessen sound distortion. Furthermore, the corrugation angle approximately below 45° is favored over other angles or flatter SPL response. Experiments are also conducted to verify the theoretical findings. 相似文献
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26.
Reliability-estimation and stopping-rules for software testing,based on repeated appearances of bugs
Software-testing (debugging) is one of the most important components in software development. An important question in the debugging process is, when to stop. The choice is usually based on one of two decision criteria: (1) when the reliability has reached a given threshold, and (2) when the gain in reliability cannot justify the testing cost. Various stopping rules and software reliability models are compared by their ability to deal with these two criteria. Two new stopping rules, initiated by theoretical study of the optimal stopping rule based on cost, are more stable than other rules for a large variety of bug structures. The 1-step-ahead stopping rules based on the Musa et. al. basic execution and logarithmic Poisson models, as well as the stopping rule by Dalal and Mallows (1990), work well for software with many relatively small bugs (bugs with very low occurrence rates). The comparison was done by simulation 相似文献
27.
BID: a novel BH3 domain-only death agonist 总被引:1,自引:0,他引:1
K Wang XM Yin DT Chao CL Milliman SJ Korsmeyer 《Canadian Metallurgical Quarterly》1996,10(22):2859-2869
The BCL-2 family of proteins consists of both antagonists (e.g., BCL-2) and agonists (e.g., BAX) that regulate apoptosis and compete through dimerization. The BH1 and BH2 domains of BCL-2 are required to heterodimerize with BAX and to repress cell death; conversely, the BH3 domain of BAX is required to heterodimerize with BCL-2 and to promote cell death. To extend this pathway, we used interactive cloning to identify Bid, which encodes a novel death agonist that heterodimerizes with either agonists (BAX) or antagonists (BCL-2). BID possesses only the BH3 domain, lacks a carboxy-terminal signal-anchor segment, and is found in both cytosolic and membrane locations. BID counters the protective effect of BCL-2. Moreover, expression of BID, without another death stimulus, induces ICE-like proteases and apoptosis. Mutagenesis revealed that an intact BH3 domain of BID was required to bind the BH1 domain of either BCL-2 or BAX. A BH3 mutant of BID that still heterodimerized with BCL-2 failed to promote apoptosis, dissociating these activities. In contrast, the only BID BH3 mutant that retained death promoting activity interacted with BAX, but not BCL-2. This BH3-only molecule supports BH3 as a death domain and favors a model in which BID represents a death ligand for the membrane-bound receptor BAX. 相似文献
28.
A study has been made of the procedures used for the lap and butt welding of 0.62 and 1.16 mm thickness steel sheets coated with Al55-Zn alloy, using laser-beam technology. The main problems arise in lap welding as a result of zinc evaporation from the coating. The vapour pressures of this element lead to cratering and blistering of the welds which are visible from the external surface and imply severe weld defects. An efficient solution to this problem consists in leaving a gap between the internal faces, thus allowing the zinc vapours to escape. Excessive gaps, however, lead to the molten metal collapse and to lack of penetration. In the present work, acceptable results were obtained with a maximum interface separation of 0.1 mm. This allows excellent continuity of the joints, without cracks, pores or non-metallic inclusions and with moderate hardnesses, thus demonstrating the good laser weldability of the coated material. A difficulty arises, however, in relation to the coating in zones close to the weld. In these high-temperature zones the coating is lost, and in the immediately adjacent areas the coating microstructure and phases are altered, as was shown by scanning electron microscope analyses. 相似文献
29.
根据我国专利法的原则,在对我国催化重整和芳烃生产专利检索过程和结果进行分析的基础上,阐述了对目前我国催化重整工艺专利市场的几点看法并提出对策。 相似文献
30.
The Fas receptor is a member of a family of cell death receptors, including tumor necrosis factor receptor I (TNFR I), death receptor 3 and 4 (DR3 and DR4), and cytopathic avian receptor 1 (CAR1). The Fas receptor is composed of several discrete domains, including three cysteine-rich domains (CRDs), a transmembrane domain, and an intracellular domain responsible for transmitting an apoptotic signal. While the mechanism of Fas-mediated cell death has become elucidated, the requirements for Fas ligand binding to the receptor have not been fully defined. Using a series of chimeric Fc-receptor fusion proteins between the human Fas receptor and TNFR I, each cysteine-rich domain of Fas was found to be required for interaction with the Fas ligand. Interestingly, TNFR I CRD1 could partially substitute for the Fas CRD1. The importance of this domain was underscored by the analysis of a Fas extracellular mutation (C66R), which resulted in a complete loss of ligand binding. This mutation was cloned from a human patient suffering from Canale-Smith syndrome, which is characterized by autoimmunity resembling that observed in the lpr and lprcg mice. The localization of essential ligand binding domains in the Fas receptor correlated exactly with the ability of the Fas receptor fusion proteins to prevent cell death mediated by the Fas ligand. 相似文献