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排序方式: 共有262条查询结果,搜索用时 13 毫秒
11.
Yoshiyuki Sano Marcekazu Konda Chan Woo Lee Yoshiharu Kimura Takeo Saegusa 《大分子材料与工程》1997,251(1):181-191
A new technique for imparting antistatic properties to poly(ethylene terephthalate) (PET) fiber has been developed. In this technique, blend polyester fibers containing poly(ethylene terephthalate/5-sulfoisophthalate) (SIP-PET) were prepared by blend spinning and then treated with various cationic surfactants in the process of dyeing. The surfactants could effectively be immobilized on the fiber as the counter cations of the sulfonate groups of the 5-sulfoisophthalate (SIP) units and aid the release of static electrons formed in the fiber. Thus, the half-life time (t1/2) of leakage of static charge and the surface resistivity (Rs) of the blend PET fibers became much lower after treating. The best result was obtained with a methylated quaternary ammonium salt of a stearylamine-ethylene oxide (EO) adduct or hydrochloride of a laurylamine-EO adduct as the surfactant of which the number of EO units was around ten. Even after five washing cycles the t1/2 value of the fibers treated with these surfactants was kept lower than 30 s with the Rs value maintained in the order of 1013 Ω cm-2. Therefore, the present technique could be useful for practical production of polyester fibers with “semi-permanent” antistatic properties which can be recovered by re-treatment even if they were lost. 相似文献
12.
Harminder Pal Singh Shalinder Kaur Sunil Mittal Daizy Rani Batish Ravinder Kumar Kohli 《Journal of chemical ecology》2009,35(2):154-162
We investigated the chemical composition and phytotoxicity of the essential oil extracted from leaves of Artemisia scoparia Waldst. et Kit. (red stem wormwood, Asteraceae). GC/GC-MS analyses revealed 33 chemical constituents representing 99.83%
of the oil. The oil, in general, was rich in monoterpenes that constitute 71.6%, with β-myrcene (29.27%) as the major constituent followed by (+)-limonene (13.3%), (Z)-β-ocimene (13.37%), and γ-terpinene (9.51%). The oil and β-myrcene were evaluated in a dose–response bioassay under laboratory conditions for phytotoxicity against three weeds—Avena fatua, Cyperus rotundus, and Phalaris minor. A significant reduction in germination, seedling growth, and dry matter accumulation was observed in the test weeds. At
the lowest treatment of 0.07 mg/ml Artemisia oil, germination was reduced by 39%, 19%, and 10.6% in C. rotundus, P. minor, and A. fatua, respectively. However, the inhibitory effect of β-myrcene was less. In general, a dose-dependent effect was observed and the growth declined with increasing concentration.
Among the three weeds, the inhibitory effect was greatest on C. rotundus, so it was selected for further studies. We explored the explanation for observed growth inhibition in terms of reactive
oxygen species (ROS: lipid peroxidation, membrane integrity, and amounts of conjugated dienes and hydrogen peroxide)-induced
oxidative stress. Exposure of C. rotundus to Artemisia oil or β-myrcene enhanced solute leakage, indicating membrane disintegration. There were increased levels of malondialdehyde and hydrogen
peroxide, indicating lipid peroxidation and induction of oxidative stress. We conclude that Artemisia oil inhibits plant root growth through generation of ROS-induced oxidative damage. 相似文献
13.
Mickey Wilson Veera Konda Kathryn Heidt Thirumurugan Rathinasabapathy Anuradha Desai Slavko Komarnytsky 《International journal of molecular sciences》2021,22(3)
Ovarian insufficiency and ovariectomy are characterized by deregulated heat loss mechanisms. Unlike hormone therapy, ERr 731 (a standardized botanical extract of Siberian rhubarb Rheum rhaponticum L. high in rhaponticin) acts like a selective estrogen receptor modulator for ERβ receptors and may offer a higher degree of safety while maintaining the desired efficacy profile. In this study, we examined the relationship between oral administration of ERr 731 and the underlying components of skin vasomotion responses in an ovariectomized (OVX) rat model. ERr 731 dose-dependently reduced tail skin temperature (Tskin) values by an average of 1 °C. The rapid onset of this effect was observed in 1 and 3 mg/kg/day ERr 731 groups as early as day 2 of administration, and remained in place for the duration of the treatment (2 weeks). Substituting ERr 731 after E2 withdrawal helped maintain body temperature similarly to E2 alone, suggesting the usefulness of ERr 731 for replacing existing hormonal therapy in humans. ERr 731 also acted as a highly selective agonist for ERβ in the hypothalamus of OVX rats, as well as in ERα/β cell-based reporter assays. These data validate the OVX/Tskin rat model as a suitable screening platform to evaluate botanical and pharmaceutical treatments of menopause, while providing further evidence for the efficacy of ERr 731 towards alleviating vasomotor menopausal symptoms and improving wellbeing during the menopausal transition. 相似文献
14.
Brandi Miller Rabina Mainali Ravinder Nagpal Hariom Yadav 《International journal of molecular sciences》2021,22(4)
The prevalence of type 2 diabetes mellitus (T2D) is increasing worldwide, and there are no long-term preventive strategies to stop this growth. Emerging research shows that perturbations in the gut microbiome significantly contribute to the development of T2D, while microbiome modulators may be beneficial for T2D prevention. However, microbiome modulators that are effective, safe, affordable, and able to be administered daily are not yet available. Based on our previous pro- and prebiotic studies, we developed a novel synbiotic yogurt comprised of human-origin probiotics and plant-based prebiotics and investigated its impact on diet- and streptozotocin-induced T2D in mice. We compared the effects of our synbiotic yogurt to those of a commercially available yogurt (control yogurt). Interestingly, we found that the feeding of the synbiotic yogurt significantly reduced the development of hyperglycemia (diabetes) in response to high-fat diet feeding and streptozotocin compared to milk-fed controls. Surprisingly, the control yogurt exacerbated diabetes progression. Synbiotic yogurt beneficially modulated the gut microbiota composition compared to milk, while the control yogurt negatively modulated it by significantly increasing the abundance of detrimental bacteria such as Proteobacteria and Enterobacteriaceae. In addition, the synbiotic yogurt protected pancreatic islet morphology compared to the milk control, while the control yogurt demonstrated worse effects on islets. These results suggest that our newly developed synbiotic yogurt protects against diabetes in mice and can be used as a therapeutic to prevent diabetes progression. 相似文献
15.
Damien Hunter Kee Heng Navdeep Mann Ravinder Anand-Ivell Richard Ivell 《International journal of molecular sciences》2021,22(8)
Xenobiotic exposure during pregnancy and lactation has been linked to perinatal changes in male reproductive outcomes and other endocrine parameters. This pilot study wished to assess whether brief maternal exposure of rats to xenobiotics dibutyl phthalate (DBP) or diethylstilbestrol (DES) might also cause long-term changes in hypothalamic gene expression or in reproductive behavior of the resulting offspring. Time-mated female Sprague Dawley rats were given either DBP (500 mg/kg body weight, every second day from GD14.5 to PND6), DES (125 µg/kg body weight at GD14.5 and GD16.5 only), or vehicle (n = 8–12 per group) and mild endocrine disruption was confirmed by monitoring postnatal anogenital distance. Hypothalamic RNA from male and female offspring at PND10, PND24 and PND90 was analyzed by qRT-PCR for expression of aromatase, oxytocin, vasopressin, ER-alpha, ER-beta, kisspeptin, and GnRH genes. Reproductive behavior was monitored in male and female offspring from PND60 to PND90. Particularly, DES treatment led to significant changes in hypothalamic gene expression, which for the oxytocin gene was still evident at PND90, as well as in sexual behavior. In conclusion, maternal xenobiotic exposure may not only alter endocrine systems in offspring but, by impacting on brain development at a critical time, can have long-term effects on male or female sexual behavior. 相似文献
16.
Muhammad Arifur Rahman Ravinder Kumar Enrique Sanchez Taras Y. Nazarko 《International journal of molecular sciences》2021,22(15)
Although once perceived as inert structures that merely serve for lipid storage, lipid droplets (LDs) have proven to be the dynamic organelles that hold many cellular functions. The LDs’ basic structure of a hydrophobic core consisting of neutral lipids and enclosed in a phospholipid monolayer allows for quick lipid accessibility for intracellular energy and membrane production. Whereas formed at the peripheral and perinuclear endoplasmic reticulum, LDs are degraded either in the cytosol by lipolysis or in the vacuoles/lysosomes by autophagy. Autophagy is a regulated breakdown of dysfunctional, damaged, or surplus cellular components. The selective autophagy of LDs is called lipophagy. Here, we review LDs and their degradation by lipophagy in yeast, which proceeds via the micrometer-scale raft-like lipid domains in the vacuolar membrane. These vacuolar microdomains form during nutrient deprivation and facilitate internalization of LDs via the vacuolar membrane invagination and scission. The resultant intra-vacuolar autophagic bodies with LDs inside are broken down by vacuolar lipases and proteases. This type of lipophagy is called microlipophagy as it resembles microautophagy, the type of autophagy when substrates are sequestered right at the surface of a lytic compartment. Yeast microlipophagy via the raft-like vacuolar microdomains is a great model system to study the role of lipid domains in microautophagic pathways. 相似文献
17.
Govindarajan Konda Naganathan Lauren M. Grimes Jeyamkondan Subbiah Chris R. Calkins Ashok Samal George E. Meyer 《Sensing and Instrumentation for Food Quality and Safety》2008,2(3):178-188
Tenderness is a primary determinant of consumer satisfaction of beef steaks. The objective of this study was to implement
and test near-infrared (NIR) hyperspectral imaging to forecast 14-day aged, cooked beef tenderness from the hyperspectral
images of fresh ribeye steaks (n = 319) acquired at 3–5 day post-mortem. A pushbroom hyperspectral imaging system (wavelength range: 900–1700 nm) with a diffuse-flood
lighting system was developed. After imaging, steaks were vacuum-packaged and aged until 14 days postmortem. After aging,
the samples were cooked and slice shear force (SSF) values were collected as a tenderness reference. After reflectance calibration,
a Region-of-Interest (ROI) of 150 × 300 pixels at the center of longissimus muscle was selected. Partial least squares regression (PLSR) was carried out on each ROI image to reduce the dimension along
the spectral axis. Gray-level textural co-occurrence matrix analysis with two quantization levels (64 and 256) was conducted
on the PLSR bands to extract second-order statistical textural features. These features were then used in a canonical discriminant
model to predict three beef tenderness categories, namely tender (SSF ≤ 205.80 N), intermediate (205.80 N < SSF < 254.80 N),
and tough (SSF ≥ 254.80 N). The model with a quantization level of 256 performed better than the one with a quantization level
of 64. This model correctly classified 242 out of 314 samples with an overall accuracy of 77.0%. Fat, protein, and water absorption
bands were identified between 900 and 1700 nm. Our results show that NIR hyperspectral imaging holds promise as an instrument
for forecasting beef tenderness. 相似文献
18.
A. V. Ramana Reddy G. Ranga Mohan D. Ravinder B. S. Boyanov 《Journal of Materials Science》1999,34(13):3169-3176
The dielectric constant () and complex dielectric constant () of zinc substituted cobalt ferrites have been measured at room temperature in the high frequency range 100 kHz to 1 MHz. The values of dielectric loss tangent (tan ) have been computed from and . Plots of dielectric constant () versus frequency show a normal dielectric behaviour of the spinel ferrites. The frequency dependence of dielectric loss tangent (tan ) is found to be abnormal, giving a peak at certain frequency for all the ferrites under investigation. A qualitative explanation is given for the composition and frequency dependence of the dielectric constant and dielectric loss tangent. The dielectric constant for these mixed ferrites is approximately inversely proportional to the square root of the resistivity. A plot of dielectric constant versus temperature shows a transition near the Curie temperature. An attempt is made to explain the possible mechanism for this observation. 相似文献
19.
This article extends the analysis of an earlier paper by the authors for a single product to lot size determination for manufacturing cycles of multiple products. The effects of production breaks, learning interactions due to commonality of tasks and different learning rates for products are considered in the formulation of an equation for the average production time per unit. The equation is applied to an equal lot size per product model. An analysis of a model restricted to equal production intervals per product per cycle is also presented. A sample problem is solved to demonstrate the application of the effects of learning to multiple product lot size determination. 相似文献
20.
Niels D. Naimon Jerzy Walczyk James S. Babb Oleksandr Khegai Xuejiao Che Leeor Alon Ravinder R. Regatte Ryan Brown Prodromos Parasoglou 《Magma (New York, N.Y.)》2017,30(3):281-289