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21.
A transcript map for the 2.8-Mb region containing the multiple endocrine neoplasia type 1 locus 总被引:1,自引:0,他引:1
22.
Debajyoti Ray P. Sunny Gils Guru P. Mohanta R. Manavalan Prafulla K. Sahoo 《应用聚合物科学杂志》2010,116(2):959-968
In this study, interpenetrating polymer network (IPN) hydrogel based on polyvinyl alcohol (PVA) networking with polyacrylic acid (PAA) were prepared by a non‐conventional emulsion method without any added crosslinker, using benzoyl peroxide as initiator and sodium chloride (NaCl) as additive. The IPN hydrogel was characterized by using Fourier transformed infrared (FTIR) spectrophotometry, Thermo gravimetric analysis (TGA), and Scanning electron microscopy (SEM). (PVA‐co‐PAA)/NaCl normal IPN hydrogel (H) were fabricated into hydrogel microspheres (HM) by modified emulsion crosslinking method using glutaraldehyde‐saturated toluene as crosslinker and were loaded with Diltiazem hydrochloride (DL). The IPN hydrogel showed more swelling in simulated intestinal fluid (SIF). (PVA‐co‐PAA)/NaCl HM formulation A1 showed comparatively higher DL entrapment (79%) and better control over DL release up to 24 h. By comparing antihypertensive activity of DL loaded two formulations in normotensive rats, HM formulation A1 found more effective in reducing blood pressure to 40.1%. The experimental results demonstrated that (PVA‐co‐PAA)/NaCl HM had the greater potential than normal hydrogel to be used as a drug carrier. A single use of the prepared hydrogel microsphere system of DL can effectively control hypertension in rats. The system holds promise for clinical studies. © 2009 Wiley Periodicals, Inc. J Appl Polym Sci, 2010 相似文献
23.
24.
Parthapratim Munshi & Tayur N. Guru Row 《Crystallography Reviews》2013,19(3):199-241
Analysis of charge density distributions in molecular crystals has received considerable attention in the last decade both from high-resolution X-ray diffraction studies and from high-level theoretical calculations. An overview of the progress made in deriving one-electron properties, intermolecular interactions in terms of the Atoms in Molecule (AIM) approach (R.F.W. Bader. Atoms in Molecules-A Quantum Theory, Clarendon, Oxford (1990), R.F.W. Bader. J. Phys. Chem., A102, 7314 (1998)) is given with special emphasis on improvements in charge density models and development of both experimental and theoretical techniques to interpret and analyse the nature of weak intermolecular interactions. The significance of the derived results from the charge density of coumarin and its derivatives have been analysed to obtain insights into the nature of intermolecular C–H?···?O, C–H?···?π, π?···?π, C–H?···?S, and S?···?S contacts. The appearance of a ‘region of overlap’ to segregate hydrogen bonds from van der Waals interactions based on the criteria proposed by Koch and Popelier (U. Koch, P.L.A. Popelier. J. Phys. Chem., 99, 9747 (1995), P.L.A. Popelier. Atoms in Molecules. An Introduction, pp. 150–153, Prentice Hall, UK (2000)) and the identification of differences in energy surfaces in concomitant polymorphs of 3-acetylcoumarin are described. 相似文献
25.
A semi-organic bisthiourea sodium fluoride (BTSF) is synthesized at ambient temperature and the single crystal of bisthiourea sodium fluoride is grown in slow evaporation technique using water as solvent. The cell parameters of the grown crystal are estimated from single crystal XRD analysis and also unambiguous assignments of fundamental modes of various molecular groups are made from the recorded FTIR and FT-Raman spectra. The thermal stability of the grown crystal is investigated using thermo-gravimetric analysis studies. Optical transmittance percentage of the grown crystal is measured from UV-VIS studies. 相似文献
26.
Brij K. Dhindaw Deba Prakash Guru Gary Purdy Hatem S. Zurob 《Transactions of the Indian Institute of Metals》2009,62(4-5):255-260
The study of single-interface transformations under controlled conditions offers insights into the similarities and distinctions between solidification and solid-solid transformations. In this contribution, we consider some parallels between the formation of a layer of ferrite on an originally austenitic steel bar and the growth of the columnar zone in the solidification of an alloy ingot. The necessary conditions for solid-solid interfacial breakdown of a decarburization front are explored and the evidence to date reviewed. The response of some Fe-C-Mn-Si steels to controlled decarburization is considered, and we present a first report of the morphological instability of a ferrite/austenite decarburization interface, and compare it with the interfacial breakdown in the solid-liquid interface. The instability is tentatively ascribed to the effects of grain-boundary nucleation and/or grain-boundary diffusion of alloying elements in austenite. Other similarities (and differences) between the growth of a ferrite layer on an alloy steel and the development of the columnar zone of an ingot are discussed. 相似文献
27.
The direct, singular, boundary element analysis (BEA) formulation has been shown to provide a basis for a computationally efficient and accurate shape structural design sensitivity analysis (DSA) approach for three-dimensional solid objects. Within the boundary element analysis context, the theoretical formulation for sensitivities of important stress-related quantities including principal and deviatoric stresses, von Mises, maximum shear, and other stress invariants are presented, both for the surface as well as the interior of a continuum structure. Numerical results are given to demonstrate the accuracy of this approach. 相似文献
28.
Richard W. Dawidek Thomas J. Hayward Ian T. Vidamour Thomas J. Broomhall Guru Venkat Mohanad Al Mamoori Aidan Mullen Stephan J. Kyle Paul W. Fry Nina-Juliane Steinke Joshaniel F. K. Cooper Francesco Maccherozzi Sarnjeet S. Dhesi Lucia Aballe Michael Foerster Jordi Prat Eleni Vasilaki Matthew O. A. Ellis Dan A. Allwood 《Advanced functional materials》2021,31(15):2008389
Emergent behaviors occur when simple interactions between a system's constituent elements produce properties that the individual elements do not exhibit in isolation. This article reports tunable emergent behaviors observed in domain wall (DW) populations of arrays of interconnected magnetic ring-shaped nanowires under an applied rotating magnetic field. DWs interact stochastically at ring junctions to create mechanisms of DW population loss and gain. These combine to give a dynamic, field-dependent equilibrium DW population that is a robust and emergent property of the array, despite highly varied local magnetic configurations. The magnetic ring arrays’ properties (e.g., non-linear behavior, “fading memory” to changes in field, fabrication repeatability, and scalability) suggest they are an interesting candidate system for realizing reservoir computing (RC), a form of neuromorphic computing, in hardware. By way of example, simulations of ring arrays performing RC approaches 100% success in classifying spoken digits for single speakers. 相似文献
29.
Ziyang Lu Guru Prakash Neupane Guohua Jia Haitao Zhao Dongchen Qi Yaping Du Yuerui Lu Zongyou Yin 《Advanced functional materials》2020,30(40)
2D materials based on main group element compounds have recently attracted significant attention because of their rich stoichiometric ratios and structure motifs. This review focuses on the phases in various 2D binary materials including III–VI, IV–VI, V–VI, III–V, IV–V, and V–V materials. Reducing 3D materials to 2D introduces confinement and surface effects as well as stabilizes unstable 3D phases in their 2D form. Their crystal structures, stability, preparation, and applications are summarized based on theoretical predictions and experimental explorations. Moreover, various properties of 2D materials, such as ferroelectric effect, anisotropic optical and electrical properties, ultralow thermal conductivity, and topological state are discussed. Finally, a few perspectives and an outlook are given to inspire readers toward exploring 2D materials with new phases and properties. 相似文献
30.
Ore sorting is a useful tool to remove gangue material from the ore and increase the quality of the ore. The vast developments in the area of artificial intelligence allow fast processing of full color digital images for the preferred investigations. Three different approaches to color texture analysis were used for the classification of associated gangue from limestone and iron ore. All the methods were based on extensions of the co-occurrence matrix method. The first approach was a correlation method, in which co-occurrence matrices are computed both between and within the color bands. In the second approach, joint color-texture features, where color features were extracted from chrominance information and texture features were extracted from luminance information of the color bands. The last approach used grey scale texture features computed on a quantized color image. Results showed that the joint color-texture method was 98% accurate for limestone and 98.4% for iron ore gangue classification. It was further observed that the features showed better accuracy with 64 grey levels quantization. 相似文献