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101.
The stability and coupling of liquid films coating the walls of a parallel-plate channel and sheared by a pressure-driven gas flow along the channel center plane is studied. The films are susceptible to a long-wavelength instability. For sufficiently low Reynolds numbers and thick gas layers, the dynamic behavior is found to be described by two coupled nonlinear partial differential equations. A linear stability analysis is conducted under the condition that the material properties and the initial undisturbed liquid-film thicknesses are equal. The linear analysis is utilized to determine whether the interfaces are predominantly destabilized by the variations of the shear stress or by the pressure gradient acting upon them. The analysis of the weakly nonlinear equations performed for this case shows that instabilities corresponding to a vanishing Reynolds number are absent from the system. Moreover, for this configuration, the patterns emerging along the two interfaces are found to be identical in the long-time limit, implying that the films are fully synchronized. A different setup, where the liquid films have identical material properties but their undisturbed thicknesses differ, is studied numerically. The results show that, even for this configuration, the interfacial waves remain phase-synchronized and closely correlated for an extended period of time. These findings are particularly relevant for gaseous flow through narrow ducts with liquid-coated walls.  相似文献   
102.
We consider families of finite elements on polygonal meshes, that are defined implicitly on each mesh cell as solutions of local Poisson problems with polynomial data. Functions in the local space on each mesh cell are evaluated via Nyström discretizations of associated integral equations, allowing for curvilinear polygons and non-polynomial boundary data. Several experiments demonstrate the approximation quality of interpolated functions in these spaces.  相似文献   
103.
Inventory based capacity control (INCAP) is a very simple method that allows inventory levels to be effectively controlled by using short-term capacity flexibility in make-to-stock settings. Moreover, INCAP can be used for finished goods inventories as well as for semi-finished goods inventories. The basic idea is to define upper and lower inventory limits and to adjust capacities if the inventory level reaches either limit. Should the inventory fall below the lower limit, capacity is increased to prevent stock-outs. Similarly, in order to avoid excess inventories the capacity is decreased should the inventory rise above the upper limit. INCAP is thus able to control inventory levels within a defined inventory range. In order to do so, it applies short term measures like over-time or extra shifts to increase capacities and cancels work hours or shifts to decrease capacities. Simulation experiments based on data from the automotive industry show that INCAP is able to improve the performance of a manufacturing system in that it significantly reduces the inventory levels necessary for guaranteeing a satisfactory service level. Overall, INCAP is found to be a straightforward but powerful method, able to cope both with uncertainties in production output as well as with varying demand. However, some restrictions do apply: INCAP depends not only on a minimum level of short-term capacity flexibility, but also in the standard set-up presented here it is limited to make-to-stock environments with similar products.  相似文献   
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It has been suggested in the literature that, although Willem Jacob ‘s Gravesande occasionally treated Newton's doctrines in a selective manner, he was nevertheless an unremitting follower of Newton's methodology. As part of a reassessment of ‘s Gravesande's Newtonianism, I argue that, although ‘s Gravesande took over key terms of Newton's methodological canon, his methodological ideas are upon close scrutiny quite different from and occasionally even incongruent with Newton's views on the matter.  相似文献   
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The objective of the REALight project is the development of a thermal process to produce lightweight aggregates in pilot scale and the implantation of a method to recover gypsum. Beside construction and demolition waste, various industrial by-products are studied as raw materials. The raw materials have so far been unused or used in applications with lower quality requirements. To prove the performance of the lightweight aggregates, their technical properties are tested and their use in different applications is studied, e.g., for lightweight mortars as well as lightweight concretes.  相似文献   
110.
    

Scope

The phytosteroid ecdysterone is present in spinach. In this study, the urinary elimination of ecdysterone and its metabolites in humans is investigated following spinach consumption of two different culinary preparations.

Methods and results

Eight participants (four males, four females) ingested 950 (27.1) g sautéed spinach (average [±standard deviation (SD)]) and 912 (70.6) g spinach smoothie as second intervention after washout. Post-administration urines are analyzed by liquid chromatography tandem mass spectrometry (LC-MS/MS). After intake of both preparations, ecdysterone and two metabolites, 14-deoxy-ecdysterone, and 14-deoxy-poststerone, are excreted in urine. The maximum concentration of ecdysterone is ranging from 0.09 to 0.41 µg mL−1 after sautéed spinach and 0.08–0.74 µg mL−1 after smoothie ingestion. The total excreted amount (mean% [±SD]) in the urine as a parent drug plus the metabolites is only 1.4 (1.0) for both sautéed spinach and smoothie. The apparent sex related differences in 14-deoxy-poststerone excretion will need further investigations.

Conclusion

Only a small proportion of ecdysterone from spinach is excreted into urine. No significant differences are found in concentration and recovered amount (%) of ecdysterone, 14-deoxy-ecdysterone, and 14-deoxy-poststerone in urine between sautéed spinach and smoothie ingestion. A discrimination between ecdysterone from food or preparations will be challenging based on urinary concentrations only, at least for later post-administration samples.  相似文献   
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