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The present study tested whether the relationships among resilience, life satisfaction, and depression could be explained by positive views toward the self, the world, and the future (positive cognitive triad). Structural equation modeling and mediation analyses were conducted based on 1,419 college students in Hong Kong. The model of positive cognitive triad as mediator between resilience and well-being fit the data (comparative fit index = .94, Tucker–Lewis index = .93, root-mean-square error of approximation = .08). Findings showed resilience to be significantly related to positive cognitions about the self, the world, and the future. Individuals who had higher level of resilience held significantly more positive cognitions and reported significantly higher levels of life satisfaction and lower levels of depression. The utility of the positive cognitive triad as the mechanism through which resilience enhances well-being was supported. Applications in cultivating resilience and positive cognitions in counseling services are discussed. (PsycINFO Database Record (c) 2011 APA, all rights reserved) 相似文献
113.
Silicon photonics has attracted tremendous attention and research effort as a promising technology in optoelectronic integration for computing, communications, sensing, and solar harvesting. Mainly due to the combination of its excellent material properties and the complementary metal–oxide semiconductor (CMOS) fabrication processing technology, silicon has becoming the material choice for photonic and optoelectronic circuits with low cost, ultra-compact device footprint, and high-density integration. This review paper provides an overview on silicon photonics, by highlighting the early work from the mid-1980s on the fundamental building blocks such as silicon platforms and waveguides, and the main milestones that have been achieved so far in the field. A summary of reported work on functional elements in both passive and active devices, as well as the applications of the technology in interconnect, sensing, and solar cells, is identified. 相似文献
114.
Bao Y. Tong Shou Yu Wang Winnie Wong-Ng Xiongnan Zhang Cong Huang Hui Zhao Weifang Liu 《Journal of the American Ceramic Society》2019,102(4):1875-1883
Hybrid improper ferroelectric Ca3Ti2O7 (CTO) ceramics were synthesized by a solid-state reaction method. Their polarization switching currents, dynamic processes of polarization-switching, and leakage current properties were investigated. It was found that the dynamic polarization curves of CTO ceramics exhibit obvious dependence on the frequency of the driving electric fields. Moreover, CTO ceramics show a switchable diode effect. The underlying mechanism for the observed effects were proposed based on the interplaying between mobile charged defects and bound charges. The charged defects also lead to a decrease in the band gap of the CTO ceramic, as revealed by absorption spectrum analysis. 相似文献
115.
Estefânia Fernandes Garcia Amanda de Oliveira Araújo Winnie Alencar Luciano Thatyane Mariano Rodrigues de Albuquerque Narciza Maria de Oliveira Arcanjo Marta Suely Madruga Marcos dos Santos Lima Marciane Magnani Maria Saarela Evandro Leite de Souza 《Journal of the science of food and agriculture》2018,98(13):5000-5010
116.
Michelle Dai Winnie Xu Helene Chesnais Nancy Anabaraonye James Parente Shampa Chatterjee Chamith S. Rajapakse 《International journal of molecular sciences》2022,23(21)
A major pathophysiological cause of cardiovascular disease is vascular plaque calcification. Fluorine 18–Sodium Fluoride (18F-NaF) PET/CT can be used as a sensitive imaging modality for detection of vascular calcification. The aim of this study was to find a non-invasive, cost-efficient, and readily available metric for predicting vascular calcification severity. This retrospective study was performed on 36 participants who underwent 18F-NaF fused PET/CT scans. The mean standard uptake values (SUVs) were calculated from manually sectioned axial sections over the aortic arch and thoracic aorta. Correlation analyses were performed between SUVs and calculated atherogenic indices (AIs). Castelli’s Risk Index I (r = 0.63, p < 0.0001), Castelli’s Risk Index II (r = 0.64, p < 0.0001), Atherogenic Coefficient (r = 0.63, p < 0.0001), Atherogenic Index of Plasma (r = 0.51, p = 0.00152), and standalone high-density lipoprotein (HDL) cholesterol (r = −0.53, p = 0.000786) were associated with aortic calcification. AIs show strong association with aortic arch and thoracic aorta calcifications. AIs are better predictors of vascular calcification compared to standalone lipid metrics, with the exception of HDL cholesterol. Clinical application of AIs provides a holistic metric beneficial for enhancing screening and treatment protocols. 相似文献
117.
Kit-lun Yick Long Wu Joanne Yip Sun-pui Ng Winnie Yu 《Journal of Materials Processing Technology》2010,210(1):116-121
Molded bras nowadays are dominating the overall bra market place, while the bra cups are mostly made of polyurethane foam sheets. The smooth and seamless inner surface of a molded bra cup gives three-dimensional nice fit to the wearer and provides unlimited designs for different softness and thickness. However, it has been a difficult question to determine the optimum molding conditions for various types of foam and there was no reliable method to measure the cup shape conformity. In this study, the properties of five polyurethane foams were investigated by thermal–mechanical analysis (TMA) and their 3D shapes formed in various molding conditions were measured by a Steinbichler Comet scanner and a new parameterization-based remesh algorithm method. The results revealed that the optimal temperature and dwell time for molding bra cups were greatly affected by the thermal–mechanical properties of polyurethane foams. The softening temperature and deformation properties of the foams tested by TMA can facilitate the determination of optimal molding temperature for the desirable cup shape and thickness. This study provides an effective and quantitative approach to eliminate the time-consuming “trial-and-error” in the molding tests traditionally being used in the industry. 相似文献
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119.
Rodrigo Teodoro Daniel Gündel Winnie Deuther-Conrad Lea Ueberham Magali Toussaint Guy Bormans Peter Brust Rare-Petru Moldovan 《International journal of molecular sciences》2021,22(15)
Cannabinoid receptors type 2 (CB2R) represent an attractive therapeutic target for neurodegenerative diseases and cancer. Aiming at the development of a positron emission tomography (PET) radiotracer to monitor receptor density and/or occupancy during a CB2R-tailored therapy, we herein describe the radiosynthesis of cis-[18F]1-(4-fluorobutyl-N-((1s,4s)-4-methylcyclohexyl)-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide ([18F]LU14) starting from the corresponding mesylate precursor. The first biological evaluation revealed that [18F]LU14 is a highly affine CB2R radioligand with >80% intact tracer in the brain at 30 min p.i. Its further evaluation by PET in a well-established rat model of CB2R overexpression demonstrated its ability to selectively image the CB2R in the brain and its potential as a tracer to further investigate disease-related changes in CB2R expression. 相似文献
120.
Daniel Gündel Masoud Sadeghzadeh Winnie Deuther-Conrad Barbara Wenzel Paul Cumming Magali Toussaint Friedrich-Alexander Ludwig Rare-Petru Moldovan Mathias Kranz Rodrigo Teodoro Bernhard Sattler Osama Sabri Peter Brust 《International journal of molecular sciences》2021,22(4)
The expression of monocarboxylate transporters (MCTs) is linked to pathophysiological changes in diseases, including cancer, such that MCTs could potentially serve as diagnostic markers or therapeutic targets. We recently developed [18F]FACH as a radiotracer for non-invasive molecular imaging of MCTs by positron emission tomography (PET). The aim of this study was to evaluate further the specificity, metabolic stability, and pharmacokinetics of [18F]FACH in healthy mice and piglets. We measured the [18F]FACH plasma protein binding fractions in mice and piglets and the specific binding in cryosections of murine kidney and lung. The biodistribution of [18F]FACH was evaluated by tissue sampling ex vivo and by dynamic PET/MRI in vivo, with and without pre-treatment by the MCT inhibitor α-CCA-Na or the reference compound, FACH-Na. Additionally, we performed compartmental modelling of the PET signal in kidney cortex and liver. Saturation binding studies in kidney cortex cryosections indicated a KD of 118 ± 12 nM and Bmax of 6.0 pmol/mg wet weight. The specificity of [18F]FACH uptake in the kidney cortex was confirmed in vivo by reductions in AUC0–60min after pre-treatment with α-CCA-Na in mice (−47%) and in piglets (−66%). [18F]FACH was metabolically stable in mouse, but polar radio-metabolites were present in plasma and tissues of piglets. The [18F]FACH binding potential (BPND) in the kidney cortex was approximately 1.3 in mice. The MCT1 specificity of [18F]FACH uptake was confirmed by displacement studies in 4T1 cells. [18F]FACH has suitable properties for the detection of the MCTs in kidney, and thus has potential as a molecular imaging tool for MCT-related pathologies, which should next be assessed in relevant disease models. 相似文献