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11.
Composition Group Vector Space (CGVS) method for estimating melting and boiling point T m , T b of organic compound has been proposed, and the principle of this method has been elucidated. The models for estimating T m , T b have been established and the numerical values of relative parameters have been presented. The average percentage deviations of T m , T b estimation are 7.53 and 1.58, respectively, which show that the present method demonstrates significant improvement in applicability to predict the above properties, compared to conventional group methods.  相似文献   
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BID: a novel BH3 domain-only death agonist   总被引:1,自引:0,他引:1  
The BCL-2 family of proteins consists of both antagonists (e.g., BCL-2) and agonists (e.g., BAX) that regulate apoptosis and compete through dimerization. The BH1 and BH2 domains of BCL-2 are required to heterodimerize with BAX and to repress cell death; conversely, the BH3 domain of BAX is required to heterodimerize with BCL-2 and to promote cell death. To extend this pathway, we used interactive cloning to identify Bid, which encodes a novel death agonist that heterodimerizes with either agonists (BAX) or antagonists (BCL-2). BID possesses only the BH3 domain, lacks a carboxy-terminal signal-anchor segment, and is found in both cytosolic and membrane locations. BID counters the protective effect of BCL-2. Moreover, expression of BID, without another death stimulus, induces ICE-like proteases and apoptosis. Mutagenesis revealed that an intact BH3 domain of BID was required to bind the BH1 domain of either BCL-2 or BAX. A BH3 mutant of BID that still heterodimerized with BCL-2 failed to promote apoptosis, dissociating these activities. In contrast, the only BID BH3 mutant that retained death promoting activity interacted with BAX, but not BCL-2. This BH3-only molecule supports BH3 as a death domain and favors a model in which BID represents a death ligand for the membrane-bound receptor BAX.  相似文献   
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用质子激发X荧光分析法测定48只家兔在挠骨骨折愈合过程中骨骼中多种微量元素含量的变化。结果表明,Fe和Sr分别呈鼓凸形和下凹形规律性变化,故Fe和Sr含量的变化可作为骨折愈合过程的指示剂。在骨折愈合过程中发现骨骼和血液中元素钙的相对含量保持不变,故无法为西医用补充钙来治疗骨折的疗法提供依据,但我们的研究结果却表明中医补充微量元素治疗骨折的疗法是有道理的。  相似文献   
16.
Xia  Lei  Lv  Jiancheng  Xie  Chunzhi  Yin  Jing 《Applied Intelligence》2021,51(11):8334-8348

In the context of human-robot and robot-robot interactions, the better cooperation can be achieved by predicting the other party’s subsequent actions based on the current action of the other party. The time duration for adjustment is not sufficient provided by short term forecasting models to robots. A longer duration can by achieved by mid-term forecasting. But the mid-term forecasting models introduce the previous errors into the follow-up forecasting and amplified gradually, eventually invalidating the forecasting. A new mid-term forecasting with error suppression based on restricted Boltzmann machine(RBM) is proposed in this paper. The proposed model can suppress the error amplification by replacing the previous inputs with their features, which are retrieved by a deep belief network(DBN). Furthermore, a new mechanism is proposed to decide whether the forecasting result is accepted or not. The model is evaluated with several datasets. The reported experiments demonstrate the superior performance of the proposed model compared to the state-of-the-art approaches.

  相似文献   
17.
Yin  Yu  Shao  Junpeng  Zhang  Lin  Cui  Qun  Wang  Haiyan 《Journal of Porous Materials》2021,28(4):1197-1213
Journal of Porous Materials - Aiming at the poor heat conduction performance of porous MIL-101 applied in adsorption cooling process, few layer graphene (FLG) was selected as a promising thermal...  相似文献   
18.
Highly conductive transparent aluminium-doped ZnO (ZnO:A1) films were successfully deposited by CW-CO2 laser-induced evaporation. Optimisation of evaporation parameters was based on laser power, substrate temperature, O2 partial pressure in the vacuum chamber and amount of Al in the ZnO source pellet. ZnO:A1 films with an electrical resistivity as low as 6.6 × 10−2Ω·cm and an optical transmission of 80% at 500nm were obtained at laser power of 15 W, substrate temperature of about 200°C, O2 partial pressure of 6—7 × 10−4 Torr and 5wt.% Al. Conductivity of ZnO films can be increased one order via Al-doping in ZnO films. The films obtained by laser-induced evaporation have compared quite favorably with the high quality films obtained by sputtering.  相似文献   
19.
本文通过在镍基自熔合金粉末中加入不同含量的稀土,研究了稀土含量对喷熔层组织及耐蚀性的影响规律及其作用机制。结果表明,在喷熔材料中加入适量稀土,可使喷熔层组织细化、晶界净化,从而使腐蚀过程中的表面活性点减少,耐蚀性提高。  相似文献   
20.
提出了锻压机械打击力测量中存在的问题,介绍了常用的补偿法,并通过实验验证了加速度补偿法是消除锻压机械打击力测量误差的有效途径。  相似文献   
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