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31.
Yanqing Ji Hao Ying John Yen Shizhuo Zhu Daniel C. Barth‐Jones Richard E. Miller R. Michael Massanari 《国际智能系统杂志》2007,22(8):827-845
Discovering unknown adverse drug reactions (ADRs) in postmarketing surveillance as early as possible is highly desirable. Nevertheless, current postmarketing surveillance methods largely rely on spontaneous reports that suffer from serious underreporting, latency, and inconsistent reporting. Thus these methods are not ideal for rapidly identifying rare ADRs. The multiagent systems paradigm is an emerging and effective approach to tackling distributed problems, especially when data sources and knowledge are geographically located in different places and coordination and collaboration are necessary for decision making. In this article, we propose an active, multiagent framework for early detection of ADRs by utilizing electronic patient data distributed across many different sources and locations. In this framework, intelligent agents assist a team of experts based on the well‐known human decision‐making model called Recognition‐Primed Decision (RPD). We generalize the RPD model to a fuzzy RPD model and utilize fuzzy logic technology to not only represent, interpret, and compute imprecise and subjective cues that are commonly encountered in the ADR problem but also to retrieve prior experiences by evaluating the extent of matching between the current situation and a past experience. We describe our preliminary multiagent system design and illustrate its potential benefits for assisting expert teams in early detection of previously unknown ADRs. © 2007 Wiley Periodicals, Inc. Int J Int Syst 22: 827–845, 2007. 相似文献
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33.
Hao Chen 《IEEE transactions on information theory / Professional Technical Group on Information Theory》2005,51(5):1854-1856
We prove a result which reduces the computation of the linear complexity of a sequence over GF(pm) (p is an odd prime) with period 2n (n is a positive integer such that there exists an element bisinGF(pm), bn=-1) to the computation of the linear complexities of two sequences with period n. By combining with some known algorithms such as the Berlekamp-Massey algorithm and the Games-Chan algorithm we can determine the linear complexity of any sequence over GF(pm) with period 2tn (such that 2 t|pm-1 and gcd(n,pm-1)=1) more efficiently 相似文献
34.
An innovative method for modelling biological processes under anaerobic conditions is presented and discussed. The method is based on titrimetric and off-gas measurements. Titrimetric data is recorded as the addition rate of hydroxyl ions or protons that is required to maintain pH in a bioreactor at a constant level. An off-gas analysis arrangement measures, among other things, the transfer rate of carbon dioxide. The integration of these signals results in a continuous signal which is solely related to the biological reactions. When coupled with a mathematical model of the biological reactions, the signal allows a detailed characterisation of these reactions, which would otherwise be difficult to achieve. Two applications of the method to the enhanced biological phosphorus removal processes are presented and discussed to demonstrate the principle and effectiveness of the method. 相似文献
35.
A systematic approach for synthesising gyrator-C active transformers using MOS transistors is presented. The topology of gyrator-C active inductors and their characteristics are briefly reviewed first. This is followed by the development of ideal gyrator-C active transformers, where only the capacitor loads of the transconductors synthesising active transformers are considered. The self and mutual inductances of both the primary and secondary windings of active transformers are investigated in detailed. Non-ideal gyrator-C active transformers are developed with the consideration of both the resistance and capacitance loads of transconductors. The intrinsic relation between the self and mutual inductances is derived. The configuration of gyrator-C active transformers with multiple primary and secondary windings is also developed. The proposed active transformers offer large and tunable self and mutual inductances with virtually no silicon area requirement. Several practical implementations of the proposed active transformers have been realised in TSMC-0.18 mum 1.8 V CMOS technology and analysed using SpectreRF with BSIM3v3 device models. Simulation results on voltage transfer characteristics, self and mutual inductances, quality factors, stability, the effect of process variations, and noise are presented. The application of the proposed active transformers is exemplified using a 1.6 GHz active transformer quadrature oscillator. 相似文献
36.
This paper studies a Kansas Department of Transportation welded plate girder bridge that developed fatigue cracks at small web gaps close to the girder top flange. Repair had been previously performed by softening the connection plate end with a slot retrofit, but cracks were recently found to have reinitiated at some of the repaired details and are again propagating. A comprehensive finite-element method study was performed to investigate the cracking behavior observed in the bridge and to recommend appropriate measures for future bridge retrofit. The analytical results show that stresses developed at the top flange web gaps could exceed yielding under the loading of an HS15 fatigue truck. The current slot repair used in the bridge was found to have introduced higher magnitude fatigue stresses in the web gap. To achieve a permanent repair of the bridge, it is recommended that a welded connection plate to flange attachment be used during future bridge retrofit. The web gap details should be able to withstand unlimited number of load cycles once this additional repair is performed. 相似文献
37.
38.
Yi‐Hung Chen Ching‐Yuan Chang Wei‐Ling Su Chun‐Yu Chiu Yue‐Hwa Yu Pen‐Chi Chiang Chiung‐Fen Chang Je‐Lueng Shie Chyow‐San Chiou Sally IM Chiang 《Journal of chemical technology and biotechnology (Oxford, Oxfordshire : 1986)》2005,80(1):68-75
This study investigates the ozonation of CI Reactive Black 5 (RB5) by using the rotating packed bed (RPB) and completely stirred tank reactor (CSTR) as ozone contactors. The RPB, which provides high gravitational force by adjusting the rotational speed, was employed as a novel ozone contactor. The same ozone dosage was separately introduced into either the RPB or the CSTR for the investigation, while the experimental solution was continuously circulated within the apparatus consisting of the RPB and CSTR. The decolorization and mineralization efficiencies of RB5 in the course of ozonation are compared for these two methods. Moreover, the dissolved and off‐gas ozone concentrations were simultaneously monitored for the further analysis. As a result, the ozone mass transfer rate per unit volume of the RPB was significantly higher because of its higher mass transfer coefficient and gas–liquid concentration driving force. Furthermore, ozonation kinetics was found to be independent of the gravitational magnitude of an ozone gas–liquid contactor. Therefore, the results suggest employing RPBs as ozone‐contacting devices with the advantage of volume reduction. The experimental results, which can be used for further modeling of the ozonation process in the RPB, also show the requirement of correct design for the RPB. Consequently, the present study is useful for the understanding of practical application of RPBs. Copyright © 2004 Society of Chemical Industry 相似文献
39.
Yuan Y. Jambunathan R. Singh J. Bhattacharya P. 《Quantum Electronics, IEEE Journal of》1997,33(3):408-415
The performance characteristics of a coupled cavity InGaAsP-InP MQW laser/active waveguide made by one-step epitaxy and well-controlled reactive ion etching (RIE) have been theoretically analyzed and experimentally determined. A theoretical model based on a finite-difference time-domain (FDTD) technique was used to simulate the propagation of an optical wave launched in the coupled system and determine the reflectivity of the facets created by RIE. The calculated effective reflectivity of the coupling region consisting of two facets and an air gap is between 0.45 and 0.55, which is in good agreement with the experimentally measured value of 0.5. The reflectivity of a single etched mirror derived from this value is estimated to be 0.3. A 120-μm-long monolithically integrated active waveguide when biased as a modulator and excited by the laser shows a maximum extinction ratio of 8 dB and a modulation bandwidth ⩾14 GHz at a dc bias of -0.5 V with a bias swing of 2 V 相似文献
40.
井巷掘进爆破工程中,工作面按设计要求,布置各种斜形炮孔,利用量角器和垂直尺控制钎杆与工作面夹角,使炮孔钻孔精度与设计炮孔角度基本上符合,在生产中取得了良好的爆破效果. 相似文献