Attitude strength and resistance processes.

This study examined whether multiple indicators of attitude strength form general dimensions that foster differential pathways to resistance. Ego involvement, certainty, personal importance, knowledge, and extremity were assessed. Resistance processes and outcomes were measured in a selective judgment paradigm. Intentions to act on attitudes and information-seeking proclivities were also assessed. Factor analyses of the strength measures revealed 2 factors. Both fostered intentions to act but were associated with differential resistance processes and outcomes. Heightened levels of the factor representing commitment to one's position were associated with increased selective elaboration, selective judgment, and attitude polarization. Embeddedness, the linkage of the attitude to one's self-concept, value system, and knowledge structure, was associated with decreased selective elaboration and increased information seeking and selective memory. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Tuning Sulfur Oxidation States on Thioether‐Bridged Peptide Macrocycles for Modulation of Protein Interactions

Thioethers, sulfoxides, and sulfonium ions, despite diverse physicochemical properties, all engage in noncovalent interactions with proteins. Thioether‐containing macrocycles are also attracting attention as protein–protein interaction (PPI) inhibitors. Here, we used a model PPI between α‐helical mixed lineage leukemia (MLL) protein and kinase‐inducible domain interacting (KIX) domain to evaluate oxidation effects on sulfurcontaining macrocycle structure, stability, and protein affinity. Desolvation effects from various polarity states were evaluated computationally and experimentally at the side chain, amino acid, and peptide level. Sulfur‐containing side chains spanned polarity ranges between all‐hydrocarbon and lactam bridges for modulating solubility, cellular uptake, and affinity. Helical propensity studies showed that, although oxidized sulfur‐containing side chains could be tolerated, conformational effects were sequence‐dependent. In some cases, proteolytic stability, binding capacity with KIX, and increased helicity were obtained as first steps toward developing PPI inhibitors.     

European American and Chinese parents' responses to children's success and failure: Implications for children's responses.

The authors examined cultural differences in parents' responses to their children's performance. In Study 1 (N = 421), Chinese 5th graders reported that their parents de-emphasized their academic success and emphasized their academic failure, whereas their American counterparts reported that their parents did the opposite. This partially accounted for Chinese (vs. American) children responding less positively to success and more negatively to failure. In Study 2 (N = 128), Chinese and American mothers' responses to their 4th and 5th graders' performance were observed in the laboratory. The cultural differences in children's reports of parents' responses documented in Study 1 were replicated; mothers' responses were also associated with children's subsequent performance. In addition, Chinese mothers were more involved than were American mothers, but their affect was similar. Taken together, the results suggest that parents' responses to children's performance may be a channel for cultural transmission and perpetuation of responses to performance. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Jitter-approximation tradeoff for periodic scheduling

We consider an asymmetric wireless communication setting, where a server periodically broadcasts data items to different mobile clients. The goal is to serve items into a prescribed rate, while minimizing the energy consumption of the mobile users. Abstractly, we are presented with a set of jobs, each with a known execution time and a requested period, and the task is to design a schedule for these jobs over a single shared resource without preemption. Given any solution schedule, its period approximation is the maximal factor by which the average period of a job in the schedule is blown up w.r.t. its requested period, and the jitter is roughly the maximal variability of times between two consecutive occurrences of the same job. Schedules with low jitter allow the mobile devices to save power by having their receivers switched off longer. In this paper we consider a scenario where clients may be willing to settle for non-optimal period approximation so that the jitter is improved. We present a parametric jitter-approximation tradeoff algorithm that allows us to choose various combinations between jitter optimality and period optimality for any given set of jobs. Zvika Brakerski was born in 1981. He received a masters’ degree from Tel-Aviv University in 2002 and is currently employed as an Electric Engineer. Boaz Patt-Shamir received his PhD from MIT in 1995. He was an assistant professor in Northeastern University until 1997, and then he joined the Dept. of Electrical Engineering in Tel Aviv University, where he directs the Computer Communication and Multimedia Laboratory. He held visiting positions at MIT, Boston University, Bellcore, and HP Labs.     

Relationship between decidual leukocyte infiltration and spontaneous abortion in a murine model of early fetal resorption

The cardiovascular effects of KRN2391, N-cyano-N'-(2-nitroxyethyl)-3-pyridine carboximidamide monomethanesulfonate, were compared with those of cromakalim and nitroglycerin in anesthetized dogs. KRN2391 (3-30 micrograms/kg, i.v.), cromakalim (3-30 micrograms/kg, i.v.) and nitroglycerin (1-10 micrograms/kg, i.v.) produced a dose-related decrease of the mean blood pressure with concomitant increase in heart rate. The increase in heart rate caused by cromakalim was lower than that caused by KRN2391 and nitroglycerin. Left ventricular end-diastolic pressure was decreased by all doses of KRN2391 and nitroglycerin. Cromakalim at 3 and 10 micrograms/kg decreased this end-diastolic pressure but increased it at 30 micrograms/kg. Left ventricular dP/dt was increased by KRN2391 and nitroglycerin but was decreased by cromakalim. KRN2391 and cromakalim produced a dose-dependent increase in aortic and coronary blood flow. Nitroglycerin showed biphasic changes in aortic and coronary blood flow, i.e., an initial increase followed by a decrease. At equipotent hypotensive doses, the increase in coronary blood flow induced by KRN2391 was greater than that by cromakalim and nitroglycerin, and total peripheral and coronary vascular resistances were decreased by KRN2391 and cromakalim. Nitroglycerin showed biphasic changes in total peripheral and coronary vascular resistances, i.e., these resistance showed an initial decrease followed by an increase. The relative decrease of coronary vascular resistance compared to the total peripheral vascular resistance was greater for KRN2391 than for cromakalim and nitroglycerin. The changes in hemodynamic parameters caused by KRN2391 were inhibited by pretreatment with glibenclamide (5 mg/kg, i.v.). These results suggest that the hemodynamic profile of KRN2391 is closer to that of cromakalim than to that of nitroglycerin, but that the selectivity for the coronary vascular bed is higher for KRN2391 than for cromakalim. In addition, it is considered that, compared with KRN2391 and nitroglycerin, cromakalim has a low selectivity for the vasculature vs the myocardium.     

Results of a digital library curriculum field test

The DL Curriculum Development project was launched in 2006, responding to an urgent need for consensus on DL curriculum across the fields of computer science and information and library science. Over the course of several years, 13 modules of a digital libraries (DL) curriculum were developed and were ready for field testing. The modules were evaluated in DL courses in real classroom environments in 37 classes by 15 instructors and their students. Interviews with instructors and questionnaires completed by their students were used to collect evaluative feedback. Findings indicate that the modules have been well designed to educate students on important topics and issues in DLs, in general. Suggestions to improve the modules based on the interviews and questionnaires were discussed as well. After the field test, module development has been continued, not only for the DL community but also others associated with DLs, such as information retrieval, big data, and multimedia. Currently, 56 modules are readily available for use through the project website or the Wikiversity site.     

Distributed discovery of large near-cliques

Given an undirected graph and 0 ￡ e ￡ 1{0\le\epsilon\le1}, a set of nodes is called an e{\epsilon}-near clique if all but an e{\epsilon} fraction of the pairs of nodes in the set have a link between them. In this paper we present a fast synchronous network algorithm that uses small messages and finds a near-clique. Specifically, we present a constant-time algorithm that finds, with constant probability of success, a linear size e{\epsilon}-near clique if there exists an e³{\epsilon^3}-near clique of linear size in the graph. The algorithm uses messages of O(log n) bits. The failure probability can be reduced to n ^−Ω(1) by increasing the time complexity by a logarithmic factor, and the algorithm also works if the graph contains a clique of size Ω(n/(log log n) ^α ) for some a ? (0,1){\alpha \in (0,1)}. Our approach is based on a new idea of adapting property testing algorithms to the distributed setting.     

Solar access of residential rooftops in four California cities

Shadows cast by trees and buildings can limit the solar access of rooftop solar-energy systems, including photovoltaic panels and thermal collectors. This study characterizes residential rooftop shading in Sacramento, San Jose, Los Angeles and San Diego, CA. Our analysis can be used to better estimate power production and/or thermal collection by rooftop solar-energy equipment. It can also be considered when designing programs to plant shade trees.High-resolution orthophotos and LiDAR (Light Detection And Ranging) measurements of surface height were used to create a digital elevation model of all trees and buildings in a well-treed 2.5–4 km² residential neighborhood. On-hour shading of roofing planes (the flat elements of roofs) was computed geometrically from the digital elevation model. Values in future years were determined by repeating these calculations after simulating tree growth. Parcel boundaries were used to determine the extent to which roofing planes were shaded by trees and buildings in neighboring parcels.For the subset of S + SW + W-facing planes on which solar equipment is commonly installed for maximum solar access, absolute light loss in spring, summer and fall peaked about 2 to 4 h after sunrise and about 2 to 4 h before sunset. The fraction of annual insolation lost to shading increased from 0.07–0.08 in the year of surface-height measurement to 0.11–0.14 after 30 years of tree growth. Only about 10% of this loss resulted from shading by trees and buildings in neighboring parcels.     

Obfuscating Conjunctions

We show how to securely obfuscate the class of conjunction functions (functions like \(f(x_1, \ldots , x_n) = x_1 \wedge \lnot x_4 \wedge \lnot x_6 \wedge \cdots \wedge x_{n-2}\)). Given any function in the class, we produce an obfuscated program which preserves the input–output functionality of the given function, but reveals nothing else. Our construction is based on multilinear maps, and can be instantiated using the recent candidates proposed by Garg, Gentry and Halevi (EUROCRYPT 2013) and by Coron et al. (CRYPTO 2013). We show that the construction is secure when the conjunction is drawn from a distribution, under mild conditions on the distribution. Security follows from multilinear entropic variants of the Diffie–Hellman assumption. We conjecture that our construction is secure for any conjunction, regardless of the distribution from which it is drawn. We offer supporting evidence for this conjecture, proving that our obfuscator is secure for any conjunction against generic adversaries.