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11.
Automatic quantification of changes in bone in serial MR images of joints   总被引:1,自引:0,他引:1  
Recent innovations in drug therapies have made it highly desirable to obtain sensitive biomarkers of disease progression that can be used to quantify the performance of candidate disease modifying drugs. In order to measure potential image-based biomarkers of disease progression in an experimental model of rheumatoid arthritis (RA), we present two different methods to automatically quantify changes in a bone in in-vivo serial magnetic resonance (MR) images from the model. Both methods are based on rigid and nonrigid image registration to perform the analysis. The first method uses segmentation propagation to delineate a bone from the serial MR images giving a global measure of temporal changes in bone volume. The second method uses rigid body registration to determine intensity change within a bone, and then maps these into a reference coordinate system using nonrigid registration. This gives a local measure of temporal changes in bone lesion volume. We detected significant temporal changes in local bone lesion volume in five out of eight identified candidate bone lesion regions, and significant difference in local bone lesion volume between male and female subjects in three out of eight candidate bone lesion regions. But the global bone volume was found to be fluctuating over time. Finally, we compare our findings with histology of the subjects and the manual segmentation of bone lesions.  相似文献   
12.
Wireless Personal Communications - A novel design of double-layer dual-band circularly polarized array antennas (DDCPAAs) is presented in this paper. First, a DDCP single antenna is introduced as...  相似文献   
13.
14.
A parametric study of linearly tapered slot antenna (LTSA) in air and a method for optimization of its pattern are presented. A method of moments code is utilized to investigate the behavior of LTSA’s as the length, height and the taper angle varies. It is shown that the antenna pattern can be improved using a top layer of dielectric material with varying permittivity.  相似文献   
15.
To speed up data‐intensive programs, two complementary techniques, namely nested loops parallelization and data locality optimization, should be considered. Effective parallelization techniques distribute the computation and necessary data across different processors, whereas data locality places data on the same processor. Therefore, locality and parallelization may demand different loop transformations. As such, an integrated approach that combines these two can generate much better results than each individual approach. This paper proposes a unified approach that integrates these two techniques to obtain an appropriate loop transformation. Applying this transformation results in coarse grain parallelism through exploiting the largest possible groups of outer permutable loops in addition to data locality through dependence satisfaction at inner loops. These groups can be further tiled to improve data locality through exploiting data reuse in multiple dimensions.  相似文献   
16.
Optimum design of chamfer distance transforms   总被引:4,自引:0,他引:4  
The distance transform has found many applications in image analysis. Chamfer distance transforms are a class of discrete algorithms that offer a good approximation to the desired Euclidean distance transform at a lower computational cost. They can also give integer-valued distances that are more suitable for several digital image processing tasks. The local distances used to compute a chamfer distance transform are selected to minimize an approximation error. A new geometric approach is developed to find optimal local distances. This new approach is easier to visualize than the approaches found in previous work, and can be easily extended to chamfer metrics that use large neighborhoods. A new concept of critical local distances is presented which reduces the computational complexity of the chamfer distance transform without increasing the maximum approximation error.  相似文献   
17.
本文研究了无线局域网中使信号频谱得到优化的一种简单OFDM子载波加载算法。此算法基于边缘自适应(Margin Adaptive)加载准则及其在室内无线信道上的性能。  相似文献   
18.
We introduce SImulation Verification with Augmentation (SIVA), a tool for coverage-directed state space search on digital hardware designs. SIVA tightly integrates simulation with symbolic techniques for efficient state space search. Specifically, the core algorithm uses a combination of ATPG and BDDs to generate directed input vectors, i.e., inputs which cover behavior not excited by simulation. We also present approaches to automatically generate lighthouses that guide the search towards hard-to-reach coverage goals. Experiments demonstrate that our approach is capable of achieving significantly greater coverage than either simulation or symbolic techniques in isolation.  相似文献   
19.
方向高频保护高压和超高压输出电线路的主要保护方式,其动作性能对电力系统的安全运行影响甚大。  相似文献   
20.
In this paper, a near-triangular buried-oxide partial silicon-on-insulator (TB-PSOI) lateral double-diffused MOS field-effect transistor is proposed. The electric field and electrostatic potential in this structure are modified by the gradual buried-oxide thickness increase. The modification includes the addition of a new peak in the electric field in comparison to that of the conventional PSOI. To assess the efficiency of the proposed structure, its breakdown voltage is compared with that of conventional PSOI using two-dimensional simulations. A comparative study is performed in terms of silicon-film and buried-oxide layer thicknesses, drift region and buried-oxide layer lengths, and drift region doping concentrations. The study shows that under the same drain current, the breakdown voltage of TB-PSOI is nearly two times higher than its PSOI counterpart (108% improvement). Simulation results show that the three-stepped oxide layer closely follows the TB-PSOI structure with a breakdown voltage improvement of 96% compared to that of the PSOI structure.  相似文献   
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