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Gilden David L.; Schmuckler Mark A.; Clayton Keith 《Canadian Metallurgical Quarterly》1993,100(3):460
The observation that natural curves and surfaces are often fractal suggests that people may be sensitive to their statistical properties. The perceptual protocols that underlie discrimination between fractals and between other types of random contour and fractals are examined. Discrimination algorithms that have precisely the same sensitivities as human observers are constructed. These algorithms do not recognize the integrated scale hierarchy intrinsic to fractal form and operate by imposing a metatheory of structure that is based on a signal–noise distinction. The success of the algorithms implies that (1) self-affinity in random fractals is not perceptually recovered and (2) people have a natural disposition to view contour in terms of signal and noise. The authors propose that this disposition be understood as a principle of perceptual organization. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
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The redistribution of spin-labeled phospholipid analogs across the plasma membrane of HepG2 cells, either in suspension or grown as monolayers, was investigated. After incorporation into the outer membrane leaflet spin-labeled aminophospholipids phosphatidylserine (PS) and phosphatidylethanolamine (PE) moved rapidly to the inner monolayer, whereas the analog of phosphatidylcholine (PC) disappeared more slowly from the outer leaflet. The fast, inward movement of the aminophospholipids was abolished after adenosine triphosphate (ATP)-depletion of cells, suggesting the presence of an aminophospholipid translocase in the plasma membrane of these cells. Compared with human red blood cells, the activity of the aminophospholipid translocase is two orders of magnitude higher in HepG2 cells. From these data, a transverse phospholipid asymmetry can be inferred with the aminophospholipids mainly concentrated on the inner monolayer and the choline-containing phospholipids on the outer leaflet. The relevance of the enrichment of PC in the outer membrane leaflet for the formation and composition of the bile is discussed. 相似文献
35.
H Shinozuka T Ohmura SL Katyal AI Zedda GM Ledda-Columbano A Columbano 《Canadian Metallurgical Quarterly》1996,23(6):1572-1577
Several proteins from culture supernatants of Streptococcus sobrinus were able to bind avidly to Sephadex G-75. The proteins could be partially eluted from the Sephadex by low-molecular-weight alpha-1,6 glucan or fully eluted by 4 M guanidine hydrochloride. Elution profiles were complex, yielding proteins of 16, 45, 58 to 60, 90, 135, and 145 kDa, showing that the wild-type strain possessed multiple glucan-binding proteins. Two mutants of Streptococcus sobrinus incapable of aggregation by high-molecular-weight alpha-1,6 glucan were isolated. One mutant was spontaneous, from a cell suspension to which glucan had been added, whereas the other was induced by ethyl methanesulfonate. Both mutants were devoid of a 60-kDa protein, as shown by gel electrophoresis of culture supernatants and whole cells. Amino acid analysis showed that the 58- to 60-kDa protein and the 90-kDa protein were distinct, although both were N-terminally blocked. Both mutants retained their ability to adhere to glass in the presence of sucrose and to ferment mannitol and sorbitol. Both mutants retained their glucosytransferase activities, as shown by activity gels. Western blots (immunoblots), employing antibody against a glucan-binding protein of Streptococcus mutans, failed to reveal cross-reactivity with S. sobrinus proteins. The results show that even though S. sobrinus produces several proteins capable of binding alpha-1,6 glucans, the 60-kDa protein is probably the lectin needed for glucan-dependent cellular aggregation. 相似文献
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Roger Norman Rothon Christopher Mark Liauw Graham Clayton Lees Wayne Christopher Edward Schofield 《The Journal of Adhesion》2002,78(7):603-628
The interaction of ammonium stearate (AS) and γ-aminopropyltriethoxysilane (APS) treatments with a magnesium hydroxide flame retardant filler and their effects on its use in an ethylene vinyl acetate copolymer compound have been investigated. The work has shown clear evidence of changes in the structure of the surface layers formed on the filler as the amount of additive is increased and the levels at which these occur can be correlated with theoretical monolayer quantities. Infrared (IR) spectroscopy data suggest that the stearate coating changes from a half salt to a full salt as the coating level is increased and that the APS coating on the filler initially has a significant bicarbonate content, presumably due to reaction with atmospheric carbon dioxide. The effect of coating level on the melt flow rate, insoluble matrix content, crystallisation behaviour, tensile properties, limiting oxygen index, and ageing of the filled compound has been studied. Distinct trends have been observed, many of which can be correlated with the structure of the filler surface layers. Of particular importance is the observation that, unlike APS, excess stearate appears to promote detrimental ageing effects. 相似文献
38.
M Korbonits PJ Trainer JA Little R Edwards PG Kopelman GM Besser F Svec AB Grossman 《Canadian Metallurgical Quarterly》1997,46(6):751-757
Modern liver surgery is based upon deep knowledge of the surgical anatomy of the liver and improvements with ultrasounds imaging techniques have provided multidimensional interpretations of the liver anatomy intraoperatively. The technical advances with real-time scanning combined with the pioneering efforts of the Japanese liver surgeons have permitted the dynamic adaptation of the functional liver anatomy to the real anatomy, thus intimately aiding in segment oriented anatomical resection. Intraoperative ultrasound afford several advantages such as viewing the internal anatomy in direct relationship to the surface landmarks under the probe, enabling higher frequencies resulting in greater image resolution. The utilization of intraoperative ultrasound can modify the tactics involved with resection of both primary and metastatic liver tumours. The routine use of intraoperative ultrasound is strongly advocated since more complex procedures can be performed safely since the surgeon proceeds with complete knowledge of the real liver anatomy when deciding the feasibility and extent of liver resection. 相似文献
39.
An original operation is proposed for localization of the diverticulum in the descending portion of the duodenum which excludes traumas of the pancreas. Clinical observations are described. 相似文献
40.
V Kamath CN Jones JC Yip BB Varasteh AH Cincotta GM Reaven YD Chen 《Canadian Metallurgical Quarterly》1997,20(11):1697-1701
OBJECTIVE: To assess the effect on various aspects of carbohydrate and lipid metabolism of administering a quick-release formulation of bromocriptine (Ergoset) to obese, nondiabetic, hyperinsulinemic women. RESEARCH DESIGN AND METHODS: Hourly concentrations of prolactin, glucose, insulin, free fatty acid (FFA), and triglyceride were measured for 24 h before and after approximately 8 weeks of treatment with Ergoset. In addition, fasting lipid and lipoprotein concentrations and the steady-state plasma glucose (SSPG) concentration in response to a continuous infusion of somatostatin, insulin, and glucose were determined before and after Ergoset administration. RESULTS: Circulating prolactin concentrations were dramatically decreased (P < 0.001) following treatment, associated with a significant fall (P < 0.05) in 24-h-long plasma glucose, FFA, and triglyceride concentrations. Neither circulating plasma insulin concentrations nor the ability of insulin to mediate glucose disposal changed with treatment. Finally, fasting total cholesterol fell (P < 0.05) and the ratio of total to HDL cholesterol decreased (P = 0.06) in association with Ergoset treatment. CONCLUSIONS: The fact that significant metabolic improvement was seen in the obese nondiabetic hyperinsulinemic women studied suggests that Ergoset could be of therapeutic benefit in clinical conditions of hyperglycemia and/or dyslipidemia. 相似文献