Loss characteristics of high-/spl epsiv//sub r/ microstrip lines fabricated by an etchable thick-film on ceramic MCM technology

Etchable thick-film multi-chip-module (MCM) technology has led to the possibility of fabricating microwave integrated circuits (MICs) with performance similar to MICs produced using more expensive conventional thin-film MCM-D techniques. However, little data is available on the loss characteristics of the technology at microwave frequencies. This paper describes an experimental investigation into the loss properties of high-definition etchable thick-film MCM microstrip lines formed on a variety of high dielectric constant (high-/spl epsiv//sub r/) ceramic substrates. Substrates investigated comprise 96% alumina (/spl epsiv//sub r/=9.5), (Zr,Sn)TiO/sub 4/(/spl epsiv//sub r/=36.6) and BaO-PbO-Nd/sub 2/O/sub 3/-TiO/sub 2/ (/spl epsiv//sub r/=90.9). Microstrip loss properties are determined by fabricating a series of loosely coupled half-wave resonators on each substrate, with a range of characteristic impedance values. Measurements to 6 GHz are compared to those for similar lines fabricated using conventional thin-film MCM-D technology. The results demonstrate that etchable thick-film MCM technology provides many of the advantages of thin-film MCM-D technology, such as low-loss and high-definition conductors, and is suitable for the cost-effective fabrication of miniaturised high-performance microstrip MICs in high volume.     

The economics of energy efficiency for the poor—a South African case study

South Africa’s Reconstruction and Development Programme set ambitious goals for providing basic services to all, including housing and electrification. More efficient use of energy has the potential to socially and politically support these goals, particularly when it is targeted at low-income communities lacking adequate energy services. This paper examines the economics of energy efficiency for the urban poor from the perspective of society, utilities and poor consumers, using five example programmes. While the five energy efficiency programmes generally have significant economic and environmental benefits from a social perspective, they may not be as attractive to utilities and consumers. Also examined are the policy options for overcoming the significant barriers to energy efficiency, and ways government can bridge the gap between what is good for society and what is good for the electricity industry.     

Individual differences in extended practice functions and solution strategies for basic addition facts.

Practice on addition basic facts and changes in solution strategies were examined in 3rd- and 4th-grade students, practicing over 3 months. Response latencies decreased, indicating positive practice effects. Each of 3 student groups demonstrated different solution–strategy mixtures. Different mixtures led to different practice effects, indexed by shifts to more efficient counting strategies and more direct retrieval. Expectations about effects of practice and instructional strategies for optimizing practice must be sensitive to a child's actual strategy pattern. Most students had decreasing latency practice functions. However, quantitative functions fit to the practice session data indicated a high proportion of cases where the latency pattern over sessions was nonmonotonic. Trends over a small number of practice sessions may be inadequate for decisions about the utility of further practice, because such data may poorly represent long-term, cumulative effects on modifying strategy usage. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

High-power etched-facet lasers

We demonstrate, for the first time, laser diodes with anetched facet fabricated by chemically assisted ion beametching, producing 1?7 W pulsed and 470mW CW output power from one facet. The devices were coated and bonded junction-side-up and tested at room temperature. The single 40 ?m stripe, 300 ?m-long devices exhibit 94 mA threshold current and differential quantum efficiencies of 80% pulsed (78% CW).     

Hyperdynamic circulation of cirrhotic rats: role of substance P and its relationship to nitric oxide

BACKGROUND: It has been suggested that excessive formation of nitric oxide (NO) is responsible for the hyperdynamic circulation observed in portal hypertension. Substance P is a neuropeptide partly cleared by the liver and causes vasodilatation through the activation of the endothelial NO pathway. However, there are no previously published data concerning the plasma level of substance P in cirrhotic rats and its relationship to NO. METHODS: Plasma concentrations of substance P and nitrate/nitrite (an index of NO production) were determined in control rats and cirrhotic rats with or without ascites using an enzyme-linked immununosorbent assay and a colorimetric assay, respectively. In addition, systemic and portal hemodynamics were evaluated by a thermodilution technique and catheterization. RESULTS: Cirrhotic rats with and without ascites had a lower systemic vascular resistance (2.6 +/- 0.2 and 3.9 +/- 0.4 mmHg ml(-1) x min x 100 g body weight, respectively) and higher portal pressure (14.6 +/- 0.6 and 11.3 +/- 1.8 mmHg) than control rats (6.5 +/- 0.3 mmHg x ml(-1) x min x 100 g BW and 6.8 +/- 0.2 mmHg, respectively, P < 0.05), and cirrhotic rats with ascites had the lowest systemic vascular resistance. Plasma levels of nitrate/nitrite progressively increased in relation to the severity of liver dysfunction (control rats, 2.7 +/- 0.5 nmol/ml; cirrhotic rats without ascites, 5.6 +/- 1.3 nmol/ml; cirrhotic rats with ascites, 8.3 +/- 2.2 nmol/ml; P < 0.05). Cirrhotic rats with ascites displayed higher plasma values of substance P (57.7 +/- 5.9 pg/ml) than cirrhotic rats without ascites (37.9 +/- 3.1 pg/ml, P < 0.05) and control rats (30.1 +/- 1.0 pg/ml, P < 0.05). There was no significant difference in plasma substance P values between control rats and cirrhotic rats without ascites (P > 0.05). No correlation was found between plasma levels of substance P and nitrate/nitrite (r = 0.318, P > 0.05). CONCLUSIONS: Excessive formation of NO may be responsible, at least partly, for the hemodynamic derangements in cirrhosis. Although substance P may not participate in the initiation of a hyperdynamic circulation in cirrhosis, it may contribute to the maintenance of the hyperdynamic circulation observed in cirrhotic rats with ascites.     

Focal segmental glomerulosclerosis in primates infected with a simian immunodeficiency virus

Focal and segmental glomerulosclerosis (FSG) with endothelial tubuloreticular inclusions (TRIs) is the typical lesion of human HIV-associated glomerulopathy. Autopsy studies showed the presence of FSG in 3 of 15 macaques dying 15-120 weeks after experimental infection with a simian immunodeficiency virus (SIVMne). Ultrastructural studies generally revealed numerous endothelial TRIs (also present in normals), mesangial expansion, and evidence of mesangial cell injury. One additional animal had a small-vessel polyarteritis with a proliferative and focally crescentic glomerulonephritis; seven animals had mild, multifocal interstitial nephritis. All animals had documented viremia after infection; 14 of 15 developed antibodies to SIV postinoculation. Additional postmortem findings included severe enterocolitis, encephalitis, and opportunistic infections. In contrast, autopsy studies of macaques infected with a type D simian retrovirus (SAIDS-D/Washington, SRV-2) for similar periods of time (n = 40) showed no evidence of FSG. One SRV-infected animal had a mild proliferative glomerulonephritis. These studies indicate SIV-infected primates may provide a relevant model for study of human HIV-associated nephropathy. They also indicate the variable pathology that can be seen in primate infections of distinct retrovirus types, each of which produces a simian immunodeficiency state that resembles human AIDS.     

Sensitization of the startle reflex by footshock: Blockade by lesions of the central nucleus of the amygdala or its efferent pathway to the brainstem.

Bilateral electrolytic lesions of the central, but not the lateral, nucleus of the amgydala blocked shock sensitization of startle (the increase in startle produced by presentation of ten 0.6-mA footshocks in rapid succession). Lesions of the central nucleus also decreased reactivity to shock (jumping and flinching) during shock presentation. However, this decrease in reactivity cannot account for the blockade of shock sensitization, because when a higher shock intensity (1.0 mA) was used, producing equivalent reactivity to that of controls at 0.6 mA, central nucleus lesions still blocked shock sensitization. Moreover, lesions of the caudal part of the ventral amygdalofugal pathway, which carries central nucleus efferents to the startle reflex pathway, also blocked shock sensitization. It is hypothesized that shock activates the central nucleus of the amygdala, which increases startle through modulation of the startle pathway. Activation of the amygdala by shock may be the unconditioned response relevant for fear conditioning. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Measurement of serum levels of exogenously administered FSH and LH during ovulation induction therapy

The available surgical and non-surgical therapy options for treatment of gallstone disease are presented. Conventional cholecystectomy is regarded as standard therapy of symptomatic cholecystolithiasis. Other modes of therapy may be indicated under certain circumstances, depending on the results of imaging procedures. In this context conventional X-ray examination, oral and intravenous cholecystography, sonography, computed tomography, endoscopic retrograde cholangiography/cholecystography, and magnetic resonance imaging are discussed and their influence on therapeutic decisions is explained.