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81.
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Hao Wu Lu Zhang Jinfan Yang Ruonan Bo Hongxu Du Kai Lin Dalin Zhang Mythili Ramachandran Yingbin Shen Yangxi Xu Xiangdong Xue Zhao Ma Aaron Raymond Lindstrom Randy Carney Tzu‐Yin Lin Yuanpei Li 《Advanced functional materials》2020,30(15)
Real‐time tracking of the dynamics change of self‐assembled nanostructures in physiological environments is crucial to improving their delivery efficiency and therapeutic effects. However, such tracking is impeded by the complex biological microenvironment leading to inhomogeneous distribution. A rotatable fluorescent ratio strategy is introduced that integrates aggregation‐induced emission (AIE) and aggregation‐caused quenching (ACQ) into one nanostructured system, termed AIE and ACQ fluorescence ratio (AAR). Following this strategy, an advanced probe, PEG5k‐TPE4‐ICGD4 (PTI), is developed to track the dynamics change. The extremely sharp fluorescent changes (up to 4008‐fold) in AAR allowed for the clear distinguishing and localization of the intact state and diverse dissociated states. The spatiotemporal distribution and structural dynamics of the PTI micelles can be tracked, quantitatively analyzed in living cells and animal tissue by the real‐time ratio map, and be used to monitor other responsive nanoplatforms. With this method, the dynamics of nanoparticle in different organelles are able to be investigated and validated by transmission electron microscopy. This novel strategy is generally applicable to many self‐assembled nanostructures for understanding delivery mechanism in living systems, ultimately to enhance their performance in biomedical applications. 相似文献
83.
Kai‐Ming Hu Yun‐Qi Liu Liang‐Wei Zhou Zhong‐Ying Xue Bo Peng Han Yan Zeng‐Feng Di Xue‐Song Jiang Guang Meng Wen‐Ming Zhang 《Advanced functional materials》2020,30(34)
Obtaining a delamination‐free wrinkled functional graphene surface in layered systems is an interesting challenge because the interface is usually too weak to withstand interfacial stress mismatch, which can trigger mechanical instability. In this paper, a general strategy is proposed toward addressing the delamination limitation imposed by fabricating conformal graphene wrinkles with bilayer systems of poly(methyl methacrylate) (PMMA) and polydimethylsiloxane (PDMS). To improve the interfacial strength, a postcuring transfer process is introduced to form a gradient interface layer without interfacial liquid between the PMMA and PDMS by entanglement of polymer chains during high‐temperature curing. Compared to the conventional wet transfer of graphene,the transfer method can greatly enhance the interfacial strength. The chemical and mechanical mechanisms underlying the enhancement are revealed both experimentally and theoretically in terms of the transition from the buckled‐induced delamination state to the delamination‐free wrinkled state. Moreover, the light diffraction behaviors of multiscale graphene wrinkles are initially demonstrated to be an interesting continuous pattern induced by overlapping. The delamination‐free conformal wrinkled functional graphene surface can provide valuable insight and design guidelines for the fundamental problems of deformed graphene and its applications in flexible functional devices. 相似文献
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小波分解尺度选择是小波去噪中的关键,分解尺度 过大或过小,都会直接影响传感信号去噪的质量。本文 通过分析常规的分解尺度选择方法,引用指标融合算法原理从图形和统计两个角度出发选用 信噪比(SNR)、均方 根误差(RMSE)、平滑度r以及信号偏差(BIAS)4项评价指标融合 成一项指标,采用指数函数对融合指标进行拟合,并提出 一种拐点判别公式来准确判定最优分解尺度。然后,采用所提方法,结合改进的阈值和阈值 函数,对实验 信号进行最佳分解尺度寻优,实验验证结果表明,本文方法所确定的最优分解尺度对应的中 心波长反射率与实际值相符,因此能够获得更优的去噪效果。 相似文献
86.
Qian-Zhong Xue Shi-Chang Zhang Pu-Kun Liu 《Journal of Infrared, Millimeter and Terahertz Waves》2005,26(10):1407-1415
A design procedure for the H10□ to H01° sector-type mode converter at Ka-band is described in detail. As an example, an H10□ to H01° sector-type mode converter with an input rectangular port size as 7.112×3.556 mm2 and another output circular port diameter as 17.2 mm is designed and measured for insertion losses and wanted mode pattern. The mode converting efficiency from H10□ mode to H01° mode is about 91.2%. The insertion losses of the converter are lower than 0.1525 dB with 2GHz band. 相似文献
87.
We show nearly 8 dB of crosstalk reduction using ground planes between active device layers in three-dimensional (3-D) integrated circuits. Our experimental work utilizes two planes of MOS transistors with tungsten or polysilicon ground planes designed to attenuate crosstalk. Theoretical simulations, using an electromagnetic solver, and the experimental results are consistent with analytical results. The key result verified is that a ground plane, whose footprint shadows the device area, is sufficiently large for effective attenuation. The interdevice layer ground plane provides an effective means to achieve crosstalk reduction in 3-D mixed-signal/RF integration because of simple fabrication and high coupling isolation. 相似文献
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时频分析作为时变非平稳信号分析的有力工具,成为现代信号处理研究的一个热点.这种分析方法提供了时间域与频率域的联合分布信息,为我们清楚地描述了信号随时间变化的关系.Wigner-Ville分布由于其良好时频集聚性,在非平稳信号分析中得到广泛应用,本文针对Wigner-Ville分布中的交叉项问题,提出了基于经验模式分解的Wigner-Ville分布,即对多分量信号运用经验模式分解,将其分解为单分量信号,再对每个单分量信号求Wigner-Ville分布进行线性叠加.提出运用相关系数法对经验模式分解伪分量进行剔除,提高了该方法的精度,并将该方法与Cohen类方法进行比较,阐述了该方法的优点. 相似文献