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111.
Effect of Gaseous Ozone on Papaya Anthracnose 总被引:1,自引:0,他引:1
Mei Kying Ong Feroz Kabir Kazi Charles F. Forney Asgar Ali 《Food and Bioprocess Technology》2013,6(11):2996-3005
Anthracnose caused by the fungus Colletotrichum gloeosporioides is considered as one of the most devastating postharvest disease of papaya. The aim of this study was to evaluate the effectiveness of gaseous ozone as a potential antifungal preservation technique to overcome anthracnose disease of papaya during cold storage. Different concentrations of ozone (0 (control), 0.04, 1.6, and 4 ppm) were applied for various exposure durations (48, 96, and 144 h). Radial mycelia growth and conidial germination were evaluated in vitro after fungal exposure to the different levels and durations of ozone. Significant inhibition in radial mycelia growth of C. gloeosporioides was observed (p?<?0.05) in all ozone treatments as compared to the control during 8 days of incubation at room temperature (25?±?3 °C). Ozone treatment of papaya fruit with 1.6-ppm ozone for 96 h delayed and simultaneously decreased the disease incidence to 40 % whereas disease severity was rated at 1.7, following 28 days of storage at 12?±?1 °C and 80 % relative humidity. The scanning electron microscopy showed that 4-ppm ozone caused disintegration of spore structure and did not affect the cuticular surface of fruit. Thus, ozone fumigation can reduce postharvest losses of papaya caused by anthracnose. 相似文献
112.
CA Lowenberger S Kamal J Chiles S Paskewitz P Bulet JA Hoffmann BM Christensen 《Canadian Metallurgical Quarterly》1999,91(1):59-69
A molecular model was built for human lecithin:cholesterol acyltransferase (LCAT) based upon the structural homology between this enzyme and lipases (Peelman et al. 1998. Prot. Sci. 7: 585-597). We proposed that LCAT belongs to the alpha/beta hydrolase fold family, and that the central domain of LCAT consists of a mixed seven-stranded beta-pleated sheet with four alpha-helices and loops linking the beta-strands. The catalytic triad of LCAT was identified as Asp345 and His377, as well as Ser181. This model is used here for the interpretation of the structural defects linked to the point mutations identified in LCAT, which cause either familial LCAT deficiency (FLD) or fish-eye disease (FED). We show that these mutations occur in separate domains of the 3D structure of the enzyme. Most mutations causing familial LCAT deficiency are either clustered in the vicinity of the catalytic triad or affect conserved structural elements in LCAT. Most mutations causing fish-eye disease are localized on the outer hydrophilic surface of the amphipathic helical segments. These mutations affect only minimally the overall structure of the enzyme, but are likely to impair the interaction of the enzyme with its co-factor and/or substrate. 相似文献
113.
The hydrolytic depolymerization of molten PET in excess water was studied using a 2 L stirred pressure reactor at temperatures of 250, 265, and 280°C. Rate constants for hydrolysis are calculated from the initial rate data. At initial water: PET charge ratios (w/w) exceeding 5.1, essentially complete depolymerization to monomer is possible at 265°C. At lower water: PET initial charges, an equilibrium is established. The equilibrium constants are calculated for 2 g water/g PET at three temperatures. A kinetic model is proposed to describe the hydrolysis reaction. The model is shown to fit experimental data and to yield good predictions for the equilibrium concentration of carboxyl groups. Carboxyl-group concentrations are measured using an end-group analysis technique. Potentiometric titrations are carried out in one of two solvent systems, dimethylphenol:chloroform or dimethylsulfoxide, depending on the extent of hydrolysis. © 1993 John Wiley & Sons, Inc. 相似文献
114.
El-Baz Amro A. Ewida M. Kamal T. Shouman M. Abbas El-Halwagi Mahmoud M. 《Clean Technologies and Environmental Policy》2004,7(1):51-61
This paper is aimed at developing a systematic and generally applicable methodology for material flow analysis in drainage systems and watersheds. In particular, this research has focused on developing a mathematical framework and application for the management of nitrogenous species (primarily ammonium ions). Nitrogen compounds are among the most important species contributing to ecological cycles. Indeed, the environmental and biological aspects of water systems and their surrounding systems are highly impacted by nitrogen compounds as they contribute to the quality, nutrition, and toxicity of these systems. A material flow model was developed to deal primarily with the water phase while including pertinent information on the solid and air phases as they interface with the water medium. Both spatial and discrete temporal dimensions were included to account for nitrogen flow and transformation. The model includes the various environmental phenomena that influence the fate and transport of targeted species (e.g., volatilization, precipitation, sedimentation, uptake by biota, adsorption, chemical and biochemical reactions, etc.). Furthermore, the model includes material flow analysis operators (or transfer functions) that characterize the system inputs and outputs as they relate to the surroundings. The aforementioned material flow analysis tools were combined in a computer-aided modeling platform to provide a complete material flow analysis and yield useful insights on the transport and fate of targeted species. The simulation results shed light on the system performance. Actual data for an Egyptian drainage system (Bahr El-Baqar) along with the outfall to Lake Manzala were used to illustrate the usefulness and applicability of the developed model. Comparison with the measured data confirmed the validity and fidelity of the model. 相似文献
115.
Multicast communication in single-hop broadcast-and-select wavelength-division multiplexing networks has received considerable attention from researchers. This article presents a comprehensive survey of the multicast scheduling techniques in this environment. It considers different challenges that are faced in the design of the multicasting techniques and presents a classification of such schemes. A survey of specific techniques is then presented and a comparison is drawn between such techniques 相似文献
116.
The most popular area of Artificial Intelligence application today is in expert systems. This paper contains a discussion of expert systems, otherwise known as knowledge-based systems and knowledge systems. The principal components of an expert system, and the evolution of expert systems are presented. The suitability of a task to an expert system is proposed. When a task is suitable for an expert system application, the system must be developed by a knowledge engineer. The methodology that the knowledge engineer must go through to develop an expert system is demostrated. Industrial engineers have formal training in many areas which can be useful when assumming the role of knowledge engineer. These areas of industrial engineering and how they are beneficial is discussed. What the future may hold in store is also pondered. 相似文献
117.
Asheesh Kumar Raghunandan Sharma Chhatrasal Gayner Siddanathi Nageswara Rao Devendra P. Singh Malay K. Das Kamal K. Kar 《International Journal of Applied Glass Science》2017,8(1):97-104
The (AgBr)x(LiPO3)(1−x) (x=0.4 and 0.5) and [(AgI)x(AgBr)0.4−x](LiPO3)0.6 (x=0.1, 0.2, and 0.3) superionic electrolytes have been prepared by conventional melt quenching using a twin roller. These electrolytes are characterized by X-ray diffraction, SEM, and energy dispersive X-ray analysis (EDAX) for structural investigation. Electrical characterizations have been carried out by the AC impedance analysis. The conductivity of LiPO3 glassy system at room temperature is improved by doping with the silver bromide (AgBr)x(LiPO3)(1−x) and the mixture of silver iodide, silver bromide (AgI-AgBr-LiPO3 system) up to 10−5 and 10−3 Ω−1 cm−1, respectively (improvements by four or five orders of magnitude). The frequency response of ionic conductivity has been analyzed by universal dynamic response model (Jonscher's law) and AC conductivity data are fitted using the Jonscher's power law. The conductivity values obtained by the power law and impedance plots are comparable. The frequency exponent (n) has a value between 0 and 1. The AgI-AgBr-LiPO3 system shows the mixed alkali effect. Summerfield scaling master curve is temperature dependent, which may be due to the contribution of the both lithium and silver ions to ionic conduction. 相似文献
118.
Snehalkumar Parmar Kamal K. Pant Mathew John Kishore Kumar Shivanand M. Pai Shalini Gupta Bharat L. Newalkar 《Journal of Porous Materials》2014,21(5):849-857
Hydroisomerization of n-hexadecane is performed over ZSM-12 framework having tailored Brønsted acidity to investigate the effect in terms of product selectivity and yield. For this purpose, pure phase of ZSM-12 (bulk molar ratio Si/Al ~ 60) has been synthesized using TEABr as a structure directing agent. The framework Brønsted acidity is tailored with group II elements (M) viz. Ca, Ba and Mg, by means of ion-exchange method. The samples so prepared have been characterized for phase purity, textural parameters, morphology by employing powder X-ray diffraction, nitrogen adsorption–desorption isotherm measurement at 77 K, and scanning electron microscopy technique, respectively. Similarly, % metal exchange is estimated using inductively coupled plasma technique. The quantification of Brønsted acidity for H+–M++–ZSM-12 samples has been estimated by means of ammonia temperature programmed desorption (NH3-TPD) and Fourier transform infrared spectroscopy of ammonia (NH3-FTIR). The well characterized H+–M++–ZSM-12 samples were loaded with Platinum (Pt, 0.5 wt%) and subjected to hydroisomerization of n-hexadecane using an up-flow fixed bed reactor to verify the effect of process parameters like temperature and WHSV. Pt/H+–Ba2+–ZSM-12 with tailored Brønsted acidity in the range of about 25 % demonstrated the optimum performance among all the catalysts with an increased isomer selectivity and yield (89.2 and 80.3 %, respectively) by about 4 wt% at a conversion level of about 90 % compared to Pt/H+–ZSM-12 framework at 568 K. Such enhancement in isomer selectivity and yield is found to be significant from commercial application point of view. Based on the obtained trend, the potential benefits of implementation of Pt/H+–Ba2+–ZSM-12 (bulk molar ratio Si/Al ~ 60) framework for cold flow property improvement of ‘bio-ATF’ have been envisaged. 相似文献
119.
Synthesis and Biological Evaluation of Benzo[b]furans as Inhibitors of Tubulin Polymerization and Inducers of Apoptosis
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Dr. Ahmed Kamal N. V. Subba Reddy V. Lakshma Nayak V. Saidi Reddy B. Prasad Vijaykumar D. Nimbarte Vunnam Srinivasulu M. V. P. S. Vishnuvardhan Prof. C. Suresh Reddy 《ChemMedChem》2014,9(1):117-128
A series of benzo[b]furans was synthesized with modification at the 5‐position of the benzene ring by introducing C‐linked substituents (aryl, alkenyl, alkynyl, etc.). These compounds were evaluated for their antiproliferative activities, inhibition of tubulin polymerization, and cell‐cycle effects. Some compounds in this series displayed excellent activity in the nanomolar range against lung cancer (A549) and renal cell carcinoma (ACHN) cancer cell lines. (6‐Methoxy‐5‐((4‐methoxyphenyl)ethynyl)‐3‐methylbenzofuran‐2‐yl)(3,4,5‐trimethoxyphenyl)methanone ( 26 ) and (E)‐3‐(6‐methoxy‐3‐methyl‐2‐(1‐(3,4,5‐trimethoxyphenyl)vinyl)benzofuran‐5‐yl)prop‐2‐en‐1‐ol ( 36 ) showed significant activity in the A549 cell line, with IC50 values of 0.08 and 0.06 μM , respectively. G2/M cell‐cycle arrest and subsequent apoptosis was observed in the A549 cell line after treatment with these compounds. The most active compound in this series, 36 , also inhibited tubulin polymerization with a value similar to that of combretastatin A‐4 (1.95 and 1.86 μM , respectively). Furthermore, detailed biological studies such as Hoechst 33258 staining, DNA fragmentation and caspase‐3 assays, and western blot analyses with the pro‐apoptotic protein Bax and the anti‐apoptotic protein Bcl‐2 also suggested that these compounds induce cell death by apoptosis. Molecular docking studies indicated that compound 36 interacts and binds efficiently with the tubulin protein. 相似文献
120.
Synthesis and Biological Evaluation of Imidazo[2,1‐b][1,3,4]thiadiazole‐Linked Oxindoles as Potent Tubulin Polymerization Inhibitors
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Dr. Ahmed Kamal M. P. Narasimha Rao Pompi Das P. Swapna Sowjanya Polepalli Vijaykumar D. Nimbarte Kishore Mullagiri Jeshma Kovvuri Dr. Nishant Jain 《ChemMedChem》2014,9(7):1463-1475
A series of imidazo[2,1‐b][1,3,4]thiadiazole‐linked oxindoles composed of an A, B, C and D ring system were synthesized and investigated for anti‐proliferative activity in various human cancer cell lines; test compounds were variously substituted at rings C and D. Among them, compounds 7 ((E)‐5‐fluoro‐3‐((6‐p‐tolyl‐2‐(3,4,5‐trimethoxyphenyl)‐imidazo[2,1‐b][1,3,4]thiadiazol‐5‐yl)methylene)indolin‐2‐one), 11 ((E)‐3‐((6‐p‐tolyl‐2‐(3,4,5‐trimethoxyphenyl)imidazo[2,1‐b][1,3,4]thiadiazol‐5‐yl)methylene)indolin‐2‐one), and 15 ((E)‐6‐chloro‐3‐((6‐phenyl‐2‐(3,4,5‐trimethoxyphenyl)imidazo[2,1‐b][1,3,4]thiadiazol‐5‐yl)methylene)indolin‐2‐one) exhibited potent anti‐proliferative activity. Treatment with these three compounds resulted in accumulation of cells in G2/M phase, inhibition of tubulin assembly, and increased cyclin‐B1 protein levels. Compound 7 displayed potent cytotoxicity, with an IC50 range of 1.1–1.6 μM , and inhibited tubulin polymerization with an IC50 value (0.15 μM ) lower than that of combretastatin A‐4 (1.16 μM ). Docking studies reveal that compounds 7 and 11 bind with αAsn101, βThr179, and βCys241 in the colchicine binding site of tubulin. 相似文献