Adaptive beamforming using the constrained Kalman filter

From the viewpoint of achieving rapid convergence, application of a Kalman filter to an adaptive array is considered. Compared with the Frost's (1972) constrained least-mean-square algorithm, the constrained Kalman algorithm for adaptive beamforming is proposed to overcome the problem of signal distortion along the look direction which occurs in the unconstrained Kalman beamformer of Baird (1974). A constraint on the array response along the look direction is added to the measurement equation of the Kalman filter. The weight vector of the constrained Kalman beamformer is derived and shown to converge to that of the minimum-variance distortionless-response beamformer. The convergence rate of the proposed algorithm is also analyzed. Compared to Baird's algorithm and the sidelobe canceller with one-step Kalman predictor, simulation results show the effectiveness of the proposed algorithm     

Critical Success Factors for Bond Financing of Construction Projects in Asia

Although bonds have been commonly used for financing construction works in developed countries such as the United States, Asian governments would like to see their construction growth increasingly funded by alternative sources such as the capital market, instead of overrelying on bank loans. Yet even in relatively active markets such as Hong Kong and Singapore, the use of bond financing for infrastructure development is limited. In a recent study based on two questionnaire surveys with subsequent interviews about retail and institutional investors, results demonstrated that credit risk was a major concern and that deterrents include lack of bond market information, illiquidity of domestic bonds, and the reliability of external credit ratings. Institutional investors, however, welcome infrastructure bonds because of the stable income stream matching their long-term commitments. To address these practical concerns, we have proposed credit and liquidity enhancement measures in this paper as the critical success factors for international construction promoters to tap into the bond market for financing construction works in Asia. Hence, this paper will be of interest to academics and practitioners who are working on project financing, because empirical findings reveal investors’ concerns, which are then addressed with recommendations.     

Quantitation of intrathecal measles virus IgG antibody synthesis rate: subacute sclerosing panencephalitis and multiple sclerosis

A method for quantitating specific anti-viral antibodies in serum and cerebrospinal fluid (CSF) is established using enzyme-linked immunosorbent assay (ELISA). Quantitated antibody levels are used to determine intrathecal specific IgG synthesis rate for the particular antibody. Measles virus was used as a model for validating this quantitative technique: a mutated form of measles virus is a cause of subacute sclerosing panencephalitis (SSPE) and there is a possibility that measles virus is related to the cause of multiple sclerosis (MS). Matched serum and CSF samples were assayed. Concentration of anti-measles IgG was determined and intrathecal measles-specific IgG synthesis rate was calculated. For the SSPE samples, measles-specific IgG synthesis rate was elevated and comprised > 20% of the total intrathecal IgG synthesis rate; these results are consistent with the literature. The ELISA method can be performed routinely, providing a quick, simple, reproducible means of quantitating specific antibody concentrations, with sensitivity greater than 1 nanogram per milliliter. With this method, quantitation of IgG antibodies to any other viral antigen can be reliably and precisely determined.     

CHL1 encodes a component of the low-affinity nitrate uptake system in Arabidopsis and shows cell type-specific expression in roots

The Arabidopsis CHL1 (AtNRT1) gene confers sensitivity to the herbicide chlorate and encodes a nitrate-regulated nitrate transporter. However, how CHL1 participates in nitrate uptake in plants is not yet clear. In this study, we examined the in vivo function of CHL1 with in vivo uptake measurements and in situ hybridization experiments. Under most conditions tested, the amount of nitrate uptake by a chl1 deletion mutant was found to be significantly less than that of the wild type. This uptake deficiency was reversed when a CHL1 cDNA clone driven by the cauliflower mosaic virus 35S promoter was expressed in transgenic chl1 plants. Furthermore, tissue-specific expression patterns showed that near the root tip, CHL1 mRNA is found primarily in the epidermis, but further from the root tip, the mRNA is found in the cortex or endodermis. These results are consistent with the involvement of CHL1 in nitrate uptake at different stages of root cell development. A functional analysis in Xenopus oocytes indicated that CHL1 is a low-affinity nitrate transporter with a K(m) value of approximately 8.5 mM for nitrate. This finding is consistent with the chlorate resistance phenotype of chl1 mutants. However, these results do not fit the current model of a single, constitutive component for the low-affinity uptake system. To reconcile this discrepancy and the complex uptake behavior observed, we propose a "two-gene" model for the low-affinity nitrate uptake system of Arabidopsis.     

Comparison of calcium phosphate cement mixture and pure calcium hydroxide as direct pulp-capping agents

This review reports the different genetic factors that have been identified either as risk factor for Alzheimer's disease (AD) or directly causing the disease. First are reviewed epidemiological data and biological mechanisms about the apoplipoprotein E gene allele epsilon 4 that is a major risk factor for Alzheimer's disease. The second part describes the mutations responsible for early-onset autosomal dominant AD found in three different genes. The gene located on chromosome 21 encodes the amyloid precusor protein (APP). The presenilin 1 and presenilin 2 genes, located on chromosome 14 and 1 respectively, encode not yet known membrane proteins.     

Efficient random subcloning of DNA sheared in a recirculating point-sink flow system

Based on a high-performance liquid chromatographic pump, we have built a device that allows recirculation of DNA through a 63-microm orifice with ensuing fractionation to a minimum fragment size of approximately 300 base pairs. Residence time of the DNA fragments in the converging flow created by a sudden contraction was found to be sufficiently long to allow extension of the DNA molecules into a highly extended conformation and, hence, breakage to occur at midpoint. In most instances, 30 passages sufficed to obtain a narrow size distribution, with >90% of the fragments lying within a 2-fold size distribution. The shear rate required to achieve breakage was found to be inversely proportional to the 1.0 power of the molecular weight. Compared with a restriction digest, up to 40% of all fragments could be cloned directly, with only marginal improvements in cloning efficiency having been observed upon prior end repair with Klenow, T4 polymerase or T4 polynucleotide kinase. Sequencing revealed a fairly random distribution of the fragments.     

Calculation of tube degradation induced by dryout instability in sodium-heated steam generators

Analytical methods are adapted and presented for the calculation of thermal fluctuations and thermal stresses experienced by a tube wall in the region of departure from nucleate boiling (DNB) in a sodium-heated steam generator. Calculated results are presented using parameter ranges and geometry adopted from the Atomics International reference design for the steam generators of the Clinch River Breeder Reactor Plant. The physical phenomenon was modeled by subjecting the tube wall and the oxide scale layer on the water side of the tube (treated as either a powdery substance or a dense protective film) to periodic water heat transfer coefficient fluctuations simulating the effect of DNB in that area of the tube. The stresses obtained were employed in estimating (where possible) the most detrimental contribution to the life expectancy of the steam generator tube based on fatigue of the tube wall and repeated exfoliation of the oxide layers.     

Transient behavior of natural circulation for boiling two-phase flow (flow after pump trip)

The idea of a flow diode has been proposed to improve the pump coastdown characteristics of the internal recirculation pumps adopted by the ABWR. In this paper, the transient behavior from forced to natural circulation was experimentally investigated by simulating a pump coastdown condition for the purpose of providing an available source of information that is necessary for designing the flow diode. The results of the study showed that the transient behavior after pump coastdown was influenced by the coastdown period, the trigger velocity and the initial driving force of natural circulation. The potential of each driving factor was governed by the delay time for boiling, which is a very important parameter in natural circulation of boiling two-phase flow. In consequence, a guide for the designing of a flow diode was proposed.