Transfected glucocorticoid receptor and certain GR fragments evoke cell death in malignant lymphoid, not myeloid cell lines

We compared the data from four growth hormone (GH) immunoassays for analyzing 24-h GH profiles in four apparently normal subjects and four obese subjects (508 serum samples). The detection limit was 0.02 microgram/L for one immunochemiluminometric assay (ICMA), 0.1 microgram/L for two IRMAs, and 0.4 microgram/L for one RIA. All GH pulses with a peak ICMA value > 1 microgram/L were detected by each of the other methods. Overall, the correlation coefficient between the values obtained with all four assays exceeded 0.90. However, for GH concentrations < or = 0.25 microgram/L, acceptable concordance (r2 > or = 0.80) was reached only between the ICMA and one IRMA; between the ICMA and the RIA, concordance was acceptable only for GH concentrations > or = 10 micrograms/L. In the normal subjects, the percentage of undetectable values was 0% with the ICMA but 29% with one of the IRMAs; in obese subjects, the corresponding values were 12% and 38%.     

Taste receptor response to sodium chloride and natriuresis in the workers and employees of an industrial enterprise

Studied in the course of one-stage epidemiologic survey of 1191 individuals were the threshold of gustatory sensitivity to table salt and nycterine natriuresis, relation of these indices to dietary habits, some risk factors for cardiovascular disorders and clinical parameters. Differing relations were established between gustatory sensitivity to table salt and natriuresis and age and gender of the examinees, the level of blood pressure, aggravated heredity in respect of arterial hypertension, smoking and alcohol abuse, this enabling one to embark upon a differential approach to dietetic correction of salt consumption.     

从复印机纸盒结构看人性化设计

静电复印机是常用的办公设备,复印时要将不同规格的复印纸装入纸盒,经常需要操作者对纸盒进行调整。从使用者的角度讲,要用最小的力气、最简便的方法来完成对机器的操纵。这就需要考虑进行人性化设计。纸盒调整主要有自动监测纸盒尺寸的功能和纸盒内侧挡板(导纸板)的调整。对比不同品牌和不同机型复印机的纸盒设计,可看出人性化设计对方便操作者使用的重要性,也为购买机器时提供了借鉴。     

路43-P1水平井高密度钻井液难点技术的解决

路43-P1井是冀中坳陷饶阳凹陷留西油田路43断块施工难度较大的一口水平井。该井上部地层泥岩吸水膨胀造浆性强；下部地层局部存在异常高温，泥岩水敏性强，易吸水膨胀，造成地层坍塌。采用高密度钻井液钻井满足了井下要求，避免了井漏，减少了复杂情况的发生，缩短了建井周期；解决了深部定向、井温高、地层压力大、地层易垮塌的问题，顺利地完成了钻井目的。     

新型水力泵排液工艺

酸化或压裂是改造油气层措施中常规的也是最有效的方法之一。问题是酸化或压裂结束后,采取何种工艺及时返排出残酸,减少残液二次沉淀对油层的污染。同时常规TCP(油管传输负压射孔)+DST(地层测试器)二联作测试工艺在遇到低压、低渗等非自喷油层时,要想取准油层产能、压力,收集到有代表性产液样品资料,困难很大。针对以上问题,大港油田钻采院研制了新型水力喷射泵,该泵可与酸化、压裂及射孔+测试等工艺配套使用,在实现一趟施工管柱同时完成几项工作的同时,利用喷射泵深抽、连续强排的技术特点,取得了较好效果。     

基于S5933的PCI总线与8051的接口设计

简要介绍了PCI总线的特点，重点介绍了AMCC公司推出的S593X系列的高性能接口控制器，并通过实践给出基于S5933的PCI总线和8051的接口设计技术。     

Effect of electric skin stimulation on the level of succinate dehydrogenase activation and changes in the parameters of glutamatergic synaptic transmission in response ro sensory stimulation

Livedo racemosa with cerebrovascular lesions has been described as Ehrmann-Sneddon syndrome. The etiopathogenetic factors provoking the vascular lesions, however, are of high diversity reaching from mechanical to autoimmune causes. We present a male patient with typical livedo racemosa, muscle pain and feeling of coldness of the forearms. By dermatohistopathology and magnetic resonance tomography of the brain, Ehrmann-Sneddon syndrome could be confirmed. At this time a chronic streptococcal infection could be diagnosed. Antibiotics, anticoagulants and vascularity-supplying therapy improved the clinical and subjective symptoms. Six months later, the patient developed dizziness, vision disorder, hypesthesia of the right forehead, malaise and weight loss. A further diagnostic workup including echocardiography revealed a myxoma of the left atrium. This report illustrates the association of Ehrmann-Sneddon syndrome with cardiac myxoma and points out that cardiac diagnostic examination should be included when dealing with small-vessel involvement of the brain.