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91.
Linda M. Gallant Cynthia Irizarry Gloria M. Boone Brenna Ruiz‐Gordon 《Journal of Computer-Mediated Communication》2010,15(4):552-574
This study explores the nature and extent of Spanish language translation of hospital websites. A quantitative content analysis of 121 U.S. hospital websites located in Hispanic communities was conducted. Results indicate that a significant number of U.S. hospitals fail on their websites to offer equal content for Spanish language users. The study also examines several factors potentially associated with the incidence of website translation. First, organizational factors such as hospital size, ownership type and formal statements of diversity commitment are investigated. Second, demographic factors such as county population size and Hispanic population size are also considered. Hispanics' use of the Internet, the digital divide, culture's impact on Internet use, and eHealth provide a background for discussion of the findings. 相似文献
92.
This article proposes two Shewhart charts, denoted npxy and npw charts, which use attribute inspection to control the mean vector (μx; μy)′ of bivariate processes. The units of the sample are classified as first‐class, second‐class, or third‐class units, according to discriminate limits and the values of their two quality characteristics, X and Y. When the npxy chart is in use, the monitoring statistic is M = N1 + N2, where N1 and N2 are the number of sample units with a second‐class and third‐class classification, respectively. When the npw chart is in use, the monitoring statistic is W = N1 + 2N2. We assume that the quality characteristics X and Y follow a bivariate normal distribution and that the assignable cause shifts the mean vector without changing the covariance matrix. In general, the synthetic npxy and npw charts require twice larger samples to outperform the T2 chart. Copyright © 2014 John Wiley & Sons, Ltd. 相似文献
93.
This article argues that the field of architecture must engage diversity in two senses of the word simultaneously: both in terms of its demographic composition and in terms of the substantive domain of architecture. Increasing the participation of women and minorities in the field should also mean increasing the substantive domain of the profession, and vice versa. We substantiate this argument within the realm of architectural education through a research study involving nearly 650 students at six different architecture schools. The purpose of the study was to investigate the ways in which both the content and the form of architectural education might impede or support the progress of women and minority students. In particular, we focus on three aspects of the “hidden curriculum”: studio pedagogy; social dynamics; and ideals and expectations. We find that women and members of some ethnic groups (particularly African-Americans and Latinos) do tend to experience the social dynamics and pedagogical practices of their educational milieu differently, often more negatively, than their male or majority counterparts. Our findings also reveal that many women and minorities feel that their career goals may be mismatched with the profession as it is currently defined. To the extent that our school programs ignore the dynamics of the hidden curriculum, not only might we be turning away potentially talented students, but we might be crippling a profession that must operate in a rapidly changing cultural and economic context. In that regard, we believe that all students will benefit from a collective reassessment of architecture's pedagogical conventions and of the definitional scope of the field. 相似文献
94.
Linda Marie Walker 《Architectural Theory Review》2013,18(2):201-220
…aporia is not something negative, not something which in fact paralyses us. but on the contrary it is an ordeal, a test, a crucial moment through which we have to go, even if we are stuck, we have to experience this moment of aporia in order to make a decision, in order to take responsibility, in order to have a future, and so on and so forth.1 相似文献
95.
Wax Ester Rich Oil From The Marine Crustacean,Calanus finmarchicus,is a Bioavailable Source of EPA and DHA for Human Consumption 下载免费PDF全文
Chad M. Cook Terje S. Larsen Linda D. Derrig Kathleen M. Kelly Kurt S. Tande 《Lipids》2016,51(10):1137-1144
Oil from the marine copepod, Calanus finmarchicus, which contains >86 % of fatty acids present as wax esters, is a novel source of n‐3 fatty acids for human consumption. In a randomized, two‐period crossover study, 18 healthy adults consumed 8 capsules providing 4 g of Calanus® Oil supplying a total of 260 mg EPA and 156 mg DHA primarily as wax esters, or 1 capsule of Lovaza® providing 465 mg EPA and 375 mg DHA as ethyl esters, each with an EPA‐ and DHA‐free breakfast. Plasma EPA and DHA were measured over a 72 h period (t = 1, 2, 4, 6, 8, 10, 12, 24, 48, and 72 h). The positive incremental area under the curve over the 72 h test period (iAUC0‐72 h) for both EPA and DHA was significantly different from zero (p < 0.0001) in both test conditions, with similar findings for the iAUC0–24 h and iAUC0–48 h, indicating the fatty acids were absorbed. There was no difference in the plasma iAUC0–72 h for EPA + DHA, or DHA individually, in response to Calanus Oil vs the ethyl ester condition; however, the iAUC0–48 h and iAUC0–72 h for plasma EPA in response to Calanus Oil were both significantly increased relative to the ethyl ester condition (iAUC0–48 h: 381 ± 31 vs 259 ± 39 μg*h/mL, p = 0.026; iAUC0‐72 h: 514 ± 47 vs 313 ± 49 μg*h/mL, p = 0.009). These data demonstrate a novel wax ester rich marine oil is a suitable alternative source of EPA and DHA for human consumption. 相似文献
96.
Importance of a Conserved Lys/Arg Residue for Ligand/PDZ Domain Interactions as Examined by Protein Semisynthesis 下载免费PDF全文
Dr. Søren W. Pedersen Griffin E. Moran Vita Sereikaitė Dr. Linda M. Haugaard‐Kedström Prof. Dr. Kristian Strømgaard 《Chembiochem : a European journal of chemical biology》2016,17(20):1936-1944
PDZ domains are ubiquitous small protein domains that are mediators of numerous protein–protein interactions, and play a pivotal role in protein trafficking, synaptic transmission, and the assembly of signaling‐transduction complexes. In recent years, PDZ domains have emerged as novel and exciting drug targets for diseases (in the brain in particular), so understanding the molecular details of PDZ domain interactions is of fundamental importance. PDZ domains bind to a protein partner at either a C‐terminal peptide or internal peptide motifs. Here, we examined the importance of a conserved Lys/Arg residue in the ligand‐binding site of the second PDZ domain of PSD‐95, by employing a semisynthetic approach. We generated six semisynthetic PDZ domains comprising different proteogenic and nonproteogenic amino acids representing subtle changes of the conserved Lys/Arg residue. These were tested with four peptide interaction partners, representing the two different binding modes. The results highlight the role of a positively charged amino acid in the β1–β2 loop of PDZ domains, and show subtle differences for canonical and noncanonical interaction partners, thus providing additional insight into the mechanism of PDZ/ligand interaction. 相似文献
97.
Jie Yin Haihong Zhu Linda Ke Panpan Hu Chongwen He Hu Zhang Xiaoyan Zeng 《The International Journal of Advanced Manufacturing Technology》2016,83(9-12):1847-1859
Laser micro sintering (LMS) is a promising technique for micro-additive manufacturing. During LMS of metallic powder, the material property variation and the heat input energy profile are important to understand physical phenomena involved. This paper presents a finite element temperature distribution profile in LMS of nickel powder on 304 stainless steel substrate. The simulation considered the transition of powder-to-dense sub-model which involves effective thermal conductivity, volumetric enthalpy, and absorptance change; and a moving volumetric Gaussian distribution heat source sub-model. It is found that, for a specified cross section, the mechanism of preheating the nickel powder changes for the heat source from previous laser-irradiated substrate region to molten nickel as the laser beam approaches, while the center of molten pool slice is slightly shifted toward the reverse direction of laser scanning when the laser moves away due to the thermal accumulation effect. Simulated sintered widths showed very good agreement with experimental measurement, and relative prediction errors are below 16 % within the process window. 相似文献
98.
Two numerical techniques, the finite difference in time domain (FDTD) and the finite element method (FEM) in frequency domain, are employed to characterize microstrip hermetic transition geometries in an effort to investigate high-frequency effects. Measurements performed on these transitions compare favorably with theory. Two different types of transitions have been analyzed from 10 to 25 GHz and have been found to be limited in performance by higher return loss as frequency increases. It is shown that microstrip-through-CPW hermetic transitions in the shielded environment may suffer from parasitic waveguide modes which, however, can be eliminated with the use of vias at appropriate locations. The hermetic wall on top of the CPW section shows a relatively small (≤ 2 dB) effect on the original circuit performance. Similarly, the hermetic bead transition shows good performance at a lower frequency region while it degrades as frequency increases. This indicates the need for very careful characterization of transitions intended for use in microwave and millimeter-wave applications. © 1996 John Wiley & Sons, Inc. 相似文献
99.
Mahsa Barzegar Rabi Behrooz Hamid Reza Mansouri Saeed Kazemi Najafi Linda F. Lorenz Charles R. Frihart 《Journal of the American Oil Chemists' Society》2020,97(12):1371-1383
Canola is widely grown in the northern latitudes for its vegetable oil, generating large quantities of residual, low value canola flour used as animal feed. The common wood adhesive poly(diphenylmethylene diisocyanate) (pMDI) should react with the wide variety of functional groups in proteins. Therefore, it would seem that canola flour with added pMDI could be an effective adhesive. Two main questions are addressed in this study: How do the wood adhesive properties of canola flour compare to the better-studied soy flour? How well do proteins, which contain an abundance of functional groups, cure with the very reactive pMDI? These questions were addressed using the small-scale adhesive strength test ASTM D-7998, with various adhesive formulations and bonding conditions for canola flour plus pMDI compared to soy adhesives. The more challenging wet cohesive bond strength was emphasized because the dry strengths were usually very good. Generally, soy adhesives were better than canola ones, as was the polyamidoamine-epichlorohydrin cross-linker compared to pMDI, but these generalizations can be altered by the conditions selected. Three-ply plywood tests supported the small-scale test results. 相似文献
100.
Rönner AC Engvall EO Andersson L Kaijser B 《International journal of food microbiology》2004,96(2):173-179
Campylobacter is today the most common cause of human bacterial enteritis in Sweden, as well as in most other industrialized countries. Common sources of infection are undercooked chicken meat, unpasteurized milk and contaminated drinking water. One aim with our present study was to identify the species Campylobacter jejuni and Campylobacter coli strains from humans and chickens using a polymerase chain reaction/restriction enzyme analysis (PCR/REA) method, as well as traditional hippurate hydrolysis test. Another aim was to investigate the antibiotic resistance pattern of the human domestic C. jejuni/C. coli isolates from infected patients and isolates from healthy Swedish chicken, as well as isolates from humans infected abroad. If discrimination between C. jejuni and C. coli was based on testing for hippurate hydrolysis, 95% of the human domestic strains and 88% of the chicken strains were identified as C. jejuni. Based on genotyping by PCR/REA, 100% of the human domestic strains and 98% of the chicken strains were attributed to C. jejuni. The E-test and disc diffusion methods were used for phenotypic antibiotic resistance studies. The two methods gave similar results. Most Swedish C. jejuni/C. coli isolates both from humans and chickens were sensitive to doxycycline and erythromycin, which are antibiotics used to treat human infection. Only 7% of the human domestic strains and 2% of the chicken strains were resistant to the quinolones tested. As a comparison, more than 94% of strains isolated from travelers to Asia and southern Europe showed antibiotic resistance to one or more drugs. 相似文献