全文获取类型
收费全文 | 525303篇 |
免费 | 7110篇 |
国内免费 | 1469篇 |
专业分类
电工技术 | 9559篇 |
综合类 | 526篇 |
化学工业 | 78657篇 |
金属工艺 | 19961篇 |
机械仪表 | 15197篇 |
建筑科学 | 12666篇 |
矿业工程 | 2269篇 |
能源动力 | 14516篇 |
轻工业 | 47053篇 |
水利工程 | 5219篇 |
石油天然气 | 9334篇 |
武器工业 | 37篇 |
无线电 | 59910篇 |
一般工业技术 | 101759篇 |
冶金工业 | 103495篇 |
原子能技术 | 10558篇 |
自动化技术 | 43166篇 |
出版年
2022年 | 3159篇 |
2021年 | 4893篇 |
2020年 | 3477篇 |
2019年 | 4553篇 |
2018年 | 7809篇 |
2017年 | 7609篇 |
2016年 | 7932篇 |
2015年 | 5559篇 |
2014年 | 9241篇 |
2013年 | 24070篇 |
2012年 | 14626篇 |
2011年 | 20144篇 |
2010年 | 15798篇 |
2009年 | 17693篇 |
2008年 | 18089篇 |
2007年 | 17775篇 |
2006年 | 15503篇 |
2005年 | 14208篇 |
2004年 | 13599篇 |
2003年 | 13397篇 |
2002年 | 12634篇 |
2001年 | 12830篇 |
2000年 | 11867篇 |
1999年 | 12595篇 |
1998年 | 32811篇 |
1997年 | 22896篇 |
1996年 | 17446篇 |
1995年 | 13033篇 |
1994年 | 11283篇 |
1993年 | 10972篇 |
1992年 | 7913篇 |
1991年 | 7418篇 |
1990年 | 7261篇 |
1989年 | 7013篇 |
1988年 | 6468篇 |
1987年 | 5766篇 |
1986年 | 5655篇 |
1985年 | 6265篇 |
1984年 | 5900篇 |
1983年 | 5170篇 |
1982年 | 4900篇 |
1981年 | 4966篇 |
1980年 | 4705篇 |
1979年 | 4609篇 |
1978年 | 4408篇 |
1977年 | 5334篇 |
1976年 | 6971篇 |
1975年 | 3796篇 |
1974年 | 3550篇 |
1973年 | 3665篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
121.
M Valenti G Cimoli S Parodi GL Mariani M Venturini P Conte P Russo 《Canadian Metallurgical Quarterly》1993,(8):1157-1161
Synergism between recombinant human tumour necrosis factor (rHuTNF) and DNA topoisomerase II inhibitor VP16 during the killing of cells has been studied in six human ovarian cancer cell lines (A2774, A2780, SW626, IGROV-1, SKOV3, Pa1) and a cervical carcinoma cell line (Me180). Studies were performed using an assay of colony formation inhibition (drug treatment for 1 h) and a growth inhibition assay (continuous exposure for 20 h). Concomitant treatment of cells with VP16+rHuTNF enhanced cell killing in all the cell lines tested--an effect observed in both short- and long-term cytotoxicity assays. This study suggests that the activity of VP16 in ovarian cancer cell lines might be enhanced by rHuTNF in in vitro models. 相似文献
122.
F. Cioffi E. M. Cohen Richard Badick 《Drug development and industrial pharmacy》1993,19(14):1741-1746
Carstensen and Rhodes1 have suggested that when, in stability programs, assays cannot be performed immediately after the protocol-designated storage time, then freezing them until such a time when assays can be performed would be a reasonable manner to retain the protocol schedule. They caution, however, that such a procedure may not be valid for dissolution data. The article to follow deals with real-time data showing that such a process is feasible for Nalidixic Acid tablets (and presumably for other tablets as well), and that, furthermore, the dissolution pattern would seem to be “frozen” as well. 相似文献
123.
124.
125.
N Pasetto V Petrozza C Ticconi A Zicari F Carpino E Piccione M Melis 《Canadian Metallurgical Quarterly》1993,35(2):99-102
Ten patients with biopsy verified chronic hepatitis C virus (HCV) infection were treated with oral ribavirin at a dose of 1,000-1,200 mg per day in two divided doses for 12 weeks. Serum alanine aminotransferase (ALT) levels and hepatitis C viral ribonucleic acid (RNA) levels in serum were followed prior to, during, and 12 weeks posttreatment. ALT levels decreased significantly in all patients during therapy from a mean level of 3.21 mukat/l (range 1.22 to 7.79) before, to 1.25 mukat/l (range 0.78 to 2.04) at the end of treatment (P < 0.005). Hereafter, relapse to pretreatment levels was seen within 12 weeks after treatment stop. The hepatitis C viral RNA levels decreased from a mean 10 log titer of 4.1 (range 1-6) before treatment to 3.4 (range 1-5) at treatment stop. Five patients did not change their HCV RNA titers during treatment. Twelve weeks posttreatment only 3 patients had lower titers than prior to treatment. We conclude that oral ribavirin seems to reduce the viral load, at least temporarily, in some patients with chronic viremic HCV infection. Further studies are needed to evaluate fully the effect of oral ribavirin on chronic HCV infection. 相似文献
126.
OBJECTIVE: To evaluate what nursing home medical directors actually do, what they and other nursing home personnel believe would be desirable to do, and what problems and deficiencies are perceived. DESIGN: Mail survey with follow-up telephone interview when necessary. SETTING: Forty-five nursing facilities in upstate New York. PARTICIPANTS: The medical directors, administrators, and directors of nursing of the 45 facilities. MEASUREMENTS: Inventory of what medical directors reported as to their actual activities and time spent, and of what they, the administrators, and the directors of nursing felt should be their responsibilities and activities under ideal circumstances. RESULTS: For part-time medical directors, self-reported time spent on medical directorship activities averaged 12 hours per month; of all directors, 45% spent 8 hours or less per month. Proportion of time spent on various specific activities varied widely. There was general agreement that substantially more time should be spent, in particular, on evaluating and addressing problems of adequacy and quality of care, communicating with attending physicians about problems, and assisting with inservice training programs. CONCLUSIONS: To fill the role adequately, more time should be spent by many part-time medical directors, which will require greater financial commitment by facilities and reimbursement systems. Efforts need to made to better coordinate the expectations of medical directors and facility staff. 相似文献
127.
128.
129.
M. Ronen 《Journal of Computer Assisted Learning》1995,11(3):141-156
Abstract This article presents a study of a large scale incorporation of one data acquisitionsystem into physics teaching in Israel. By 1994 about 30% of the schools throughout the country used the V-scope, a 3-D multibody motion tracing system, in their lab programme. The views and reactions of post-training teachers, experienced teachers and students on various aspects of using the system are described, analysed and compared. 相似文献
130.