Acoustic microscopy and nonlinear effects in pressurized superfluid helium

The operation of an acoustic microscope having a resolution of 15 mm has been demonstrated. It uses as a coupling medium superfluid (4 )He colder than 0.9 K and pressurized to greater than 20 bar. The microscope has been used to image objects that show little or no contrast on a scanning electron microscope. In addition, the acoustic microscope has been used to study the properties of sound propagation in the coupling fluid. At low acoustic intensities, the coupling fluid has very low acoustic attenuation at the microscope's operating frequency (15.3 GHz), but near the focal point the acoustic intensity can be high enough that the helium behaves with extreme nonlinearity. In fact, this medium is capable of entering new regimes of nonlinear interaction. Plots of the received signal versus input power display a nearly complete source depletion at certain input power levels and a reconversion to the source frequency at higher power levels. Arguments that the process underlying this nonlinear behavior is harmonic generation are presented.     

电能质量综合指标评价方法研究

文章首先回顾了现有电能质量指标的评价方法,包括单一监测点单一指标及多指标综合评价、同电压等级下多监测点单一指标综合评价方法;在此基础上,文章提出了一种包括所有电压等级的系统性多监测点多指标综合评价方法.算例分析结果表明:该方法适用于从时间域、空间域两个维度得到统一的电能质量综合指标,以实现不同区域电能质量综合指标的全面评估比较.     

Structure and catalytic activity of highly ordered AlMCM-48 materials with different Si/Al ratios on the degradation of high-density polyethylene

Journal of Porous Materials - Catalysts of AlMCM-48 with different Si/Al molar rations were synthesized by modified hydrothermal method with respect to previous works. As a consequence, the...     

Secondary Metabolic Profile as a Tool for Distinction and Characterization of Cultivars of Black Pepper (Piper nigrum L.) Cultivated in Pará State,Brazil

This study evaluated the chemical compositions of the leaves and fruits of eight black pepper cultivars cultivated in Pará State (Amazon, Brazil). Hydrodistillation and gas chromatography–mass spectrometry were employed to extract and analyze the volatile compounds, respectively. Sesquiterpene hydrocarbons were predominant (58.5–90.9%) in the cultivars “Cingapura”, “Equador”, “Guajarina”, “Iaçará”, and “Kottanadan”, and “Bragantina”, “Clonada”, and “Uthirankota” displayed oxygenated sesquiterpenoids (50.6–75.0%). The multivariate statistical analysis applied using volatile composition grouped the samples into four groups: γ-Elemene, curzerene, and δ-elemene (“Equador”/“Guajarina”, I); δ-elemene (“Iaçará”/“Kottanadan”/“Cingapura”, II); elemol (“Clonada”/“Uthirankota”, III) and α-muurolol, bicyclogermacrene, and cubebol (“Bragantina”, IV). The major compounds in all fruit samples were monoterpene hydrocarbons such as α-pinene, β-pinene, and limonene. Among the cultivar leaves, phenolics content (44.75–140.53 mg GAE·g⁻¹ FW), the enzymatic activity of phenylalanine-ammonia lyase (20.19–57.22 µU·mL⁻¹), and carotenoids (0.21–2.31 µg·mL⁻¹) displayed significant variations. Due to black pepper’s susceptibility to Fusarium infection, a molecular docking analysis was carried out on Fusarium protein targets using each cultivar’s volatile components. F. oxysporum endoglucanase was identified as the preferential protein target of the compounds. These results can be used to identify chemical markers related to the susceptibility degree of black pepper cultivars to plant diseases prevalent in Pará State.     

Target Score—A Proteomics Data Selection Tool Applied to Esophageal Cancer Identifies GLUT1-Sialyl Tn Glycoforms as Biomarkers of Cancer Aggressiveness

Esophageal cancer (EC) is a life-threatening disease, demanding the discovery of new biomarkers and molecular targets for precision oncology. Aberrantly glycosylated proteins hold tremendous potential towards this objective. In the current study, a series of esophageal squamous cell carcinomas (ESCC) and EC-derived circulating tumor cells (CTCs) were screened by immunoassays for the sialyl-Tn (STn) antigen, a glycan rarely expressed in healthy tissues and widely observed in aggressive gastrointestinal cancers. An ESCC cell model was glycoengineered to express STn and characterized in relation to cell proliferation and invasion in vitro. STn was found to be widely present in ESCC (70% of tumors) and in CTCs in 20% of patients, being associated with general recurrence and reduced survival. Furthermore, STn expression in ESCC cells increased invasion in vitro, while reducing cancer cells proliferation. In parallel, an ESCC mass spectrometry-based proteomics dataset, obtained from the PRIDE database, was comprehensively interrogated for abnormally glycosylated proteins. Data integration with the Target Score, an algorithm developed in-house, pinpointed the glucose transporter type 1 (GLUT1) as a biomarker of poor prognosis. GLUT1-STn glycoproteoforms were latter identified in tumor tissues in patients facing worst prognosis. Furthermore, healthy human tissues analysis suggested that STn glycosylation provided cancer specificity to GLUT1. In conclusion, STn is a biomarker of worst prognosis in EC and GLUT1-STn glycoforms may be used to increase its specificity on the stratification and targeting of aggressive ESCC forms.     

基于语义分析的设计实体智能搜索

本文提出了在设计联盟组织过程中实现互联网上设计实体智能搜索的方法。根据对互联网上设计实体搜索问题的分析建立了设计实体智能搜索策略；定义了提取设计实体查询向量和描述向量的语义分析规则；提出了基于语义分析的设计实体智能搜索算法；最后编程实现了各项功能。     

基于FPGA&ASIC的专用USB接口设计与实现

无驱型USB KEY专用接口的设计和实现是基于FPGA&ASIC的. 该设计主要使用Verilog语言在FPGA上实现USB协议,并提供针对USB收发器和微控制器的接口. 通过该接口USB KEY在接入系统后不需要驱动程序即可正常使用. 该设计通过了软件的仿真并在FPGA上进行了硬件验证.     

Direct-Ink-Writing of Electroactive Polymers for Sensing and Energy Storage Applications

Considering the high levels of materials used in the fields of electronics and energy storage systems, it is increasingly necessary to take into consideration environmental impact. Thus, it is important to develop devices based on environmentally friendlier materials and/or processes, such as additive manufacturing techniques. In this work, poly(vinylidene fluoride) (PVDF) and poly(vinylidene fluoride-co-hexafluoropropylene) (PVDF-HFP) are prepared by direct-ink-writing (DIW) by varying solvent evaporation temperature and fill density percentage. Different morphologies for both polymers are obtained, including dense films and porous membranes, as well as different electroactive β-phase content, thermal and mechanical properties. The dielectric constant and piezoelectric d₃₃ coefficient for dense films reaches up to 16 at 1 kHz and 4 pC N⁻¹, respectively for PVDF-HFP with a fill density of 80 and a solvent evaporation temperature of 50 °C. Porous structures are developed for battery separator membranes in lithium-ion batteries, with a highest ionic conductivity value of 3.8 mS cm⁻¹ for the PVDF-HFP sample prepared with a fill density of 100 and a solvent evaporation temperature of 25 °C, the sample showing an excellent cycling performance. It is demonstrated that electroactive films and membranes can be prepared by direct-ink writing suitable for sensors/actuators and energy storage systems.     

管桩水泥性能优化与控制方法

预应力高强管桩是采用高标号品种水泥等原料作为原材料,经离心工艺成型后,再通过蒸汽或蒸压养护而成的一种空心圆筒体的等截面混凝土构件,具有脱模快、强度高、施工方便、适用范围广、生产成本低等优点,广泛应用于建筑、港口、码头、铁路、桥梁等基础设施建设工程中[1]。管桩制品厂家一般对水泥强度要求高,尤其是早期强度[2],另外因操作时间不长和对产品外观质量要求较高,相比普通的混凝土,对流动性要求更高。中国葛洲坝水泥有限公司长期向荆州、荆门等地的管桩生产企业供应管桩专用水泥,为更好地满足客户需求,提升公司管桩水泥产品的强度与工作流动性能,开展相关试验研究。