Remote Field Eddy Current Control Using Rotating Magnetic Field Transducer: Application to Pressure Tubes Examination

The remote field eddy current (RFEC) technique is used to investigate the possibility of detecting the discontinuities practiced on pressure tubes samples from nuclear reactors, pressurized heavy water reactors (PHWR) type. In this article, we propose to develop the RFEC using the technique of rotating magnetic field (RMF). A method for calculating the field generated by the eddy current transducer with RMF using propagator matrix was developed. The experimental measurements are realized for artificial discontinuities practiced in pressure tubes samples.     

A Focus on Unusual ECL2 Interactions Yields β2-Adrenergic Receptor Antagonists with Unprecedented Scaffolds

The binding pockets of aminergic G protein-coupled receptors are often targeted by drugs and virtual screening campaigns. In order to find ligands with unprecedented scaffolds for one of the best-investigated receptors of this subfamily, the β₂-adrenergic receptor, we conducted a docking-based screen insisting that molecules would address previously untargeted residues in extracellular loop 2. We here report the discovery of ligands with a previously undescribed coumaran-based scaffold. Furthermore, we provide an analysis of the added value that X-ray structures in different conformations deliver for such docking screens.     

Synthesis, characterization and drug release properties of thermosensitive poly(N-isopropylacrylamide) microgels

Nanocomposite membranes (NCMs) were prepared by using the solution casting technique by incorporating the different amounts like 6, 8, 10 wt.% of Preyssler type heteropolyacid nanoparticles to the sodium alginate. Prepared NCMs were utilized for the sorption and permeation studies for the aqueous isopropanol solutions at different concentrations. Sorption experiment enabled the study of interactions between the components of the mixture and the polymer. Flory-Huggins interaction parameters between the permeating molecules and polymer and solubility parameters were determined to explain the sorption behavior of the NCMs. Permeation properties of the NCMs were tested by applying them for pervaporation dehydration of IPA at different concentrations. Different PV parameters like separation factor, flux, Permeance and selectivity were calculated to explain the permeation behavior of the NCMs. In this study, increased sorption, permeation and selectivity was observed for the NCMs than pristine sodium alginate membrane, indicating that NCMs are efficient for PV dehydration of the IPA. Solution-diffusion model was adopted to study the mass transfer through the membrane by calculating the diffusion coefficients.