双极高压直流输电线路行波差动保护原理及方案

针对现时保护方案的不足,提出了双极高压直流输电系统直流线路行波差动保护原理和方案。该方案利用直流线路两端反行波的1模分量构造行波差动保护判据,其中行波差动量和制动量分别利用线路整流侧反行波和逆变侧传播来的反行波间的差量及二者之和构成,并利用整流侧电流的零模分量来判断双极运行时的故障线路。仿真结果表明,所提出的保护判据具有更高的灵敏度、可靠性和安全性,最大抗过渡电阻能力提高到500？,并且在各种故障情况下都能够正确动作。     

Preparedness and phobias: A review.

The preparedness theory of phobia holds that humans are biologically prepared to learn to fear objects and situations that threatened the survival of the species throughout its evolutionary history (Seligman, 1971). Biological preparedness is postulated to be responsible for the rapid acquisition, irrationality, belongingness, and high resistance to extinction considered characteristic of phobias. Psychophysiological experiments testing this theory have involved comparisons between fear-relevant stimuli (e.g., slides of snakes) and fear-irrelevant stimuli (e.g., slides of flowers) as conditioned stimuli in Pavlovian aversive conditioning paradigms. Researchers have predicted that autonomic responses conditioned to fear-relevant stimuli should mimic the aforementioned characteristics of phobias. The evidence most consistent with the theory is the enhanced resistance to extinction of electrodermal responses established to fear-relevant stimuli. Hypotheses regarding ease of acquisition, irrationality, and belongingness have received either only minimal or equivocal support. Alternative explanations are discussed for the resistance to extinction effect, the conceptual basis of preparedness theory, and its clinical implications. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Effect of increasing temperature on the properties of four bone cements

This investigation uses a laboratory model to evaluate the effects of a heated femoral stem on the biomechanical properties of four common acrylic bone cements. American Society for Testing Materials dog bone shaped acrylic cement specimens made at four test temperatures, 0 degree C, 23 degrees C, 37 degrees C and 50 degrees C, were tested for modulus, ultimate tensile strength, fracture toughness, and percent porosity. Fatigue strength was tested in Simplex P at 23 degrees C and 37 degrees C. The data allow direct comparison among four cement brands at each of the four temperature conditions. No adverse changes of the mechanical properties were found for any cement at any temperature. Modulus, fracture toughness, and fatigue strength were unaffected by increased temperature. Ultimate tensile strength increased in Simplex P and Zimmer Osteobond but was unaffected for Zimmer Regular and Palacos R cements. Percent porosity was related to temperature changes inversely in all brands studied, except for Palacos R which consistently had low porosity, unaffected by temperature variation. Fatigue strength of Simplex P was unaffected by heating to 37 degrees C. Based on this laboratory model, heating of the femoral stem could save time without sacrificing mechanical properties of acrylic bone cement.     

New genes for male accessory gland proteins in Drosophila melanogaster

The accessory gland of male insects produces components of the seminal fluid that alter the behavior, physiology and life span of the mated female, and contribute to her efficient storage and utilization of sperm. As a step towards understanding how this occurs, we have isolated genes encoding 12 previously unreported accessory gland-specific mRNAs from the fruit fly Drosophila melanogaster. We report here the restriction maps of the new genes, the chromosome positions--which are all autosomal--of the 11 non-repetitive genes, their expression patterns, and the sequences of the accessory gland proteins (Acps) encoded by nine of the genes. Eight of the proteins predicted from these sequences begin with putative secretion signals. Following their signal sequences, three of the predicted molecules are peptides and the other five are larger polypeptides with characteristics of cleavable prohormones. The ninth molecule, which has an N-terminal hydrophobic region but no consensus signal peptide cleavage site, is predicted to be a 716 amino acid glycoprotein. Of the nine proteins, two have intriguing similarities to sequences in protein databases. Acp76A is a 388 amino acid pro-protein which contains a signature sequence for the serpin class of protease inhibitors. The 115 amino acid Acp62F has a 28 amino acid region of high sequence similarity to a neurotoxin of the Brazilian armed spider Phoneutria nigriventer. Models are discussed in which Acp76A plays a role in the observed regulation of Acp proteolysis and/or in the coagulation of seminal fluid to form a mating plug, and in which Acp62F contributes to the reported toxicity of Drosophila seminal fluid.     

Glucocorticoid binding in mammary tissue slices of cattle in various reproductive states

Unlabeled cortisol and dexamethasone reduced tritiated cortisol and tritiated dexamethasone binding to 700 X g supernatant and precipitate fractions of mammary tissue slices from virgin heifers and from multiparous cows that were 1-mo prepartum (nonlactating), lactating (non-pregnant), or dry (nonpregnant, nonlactating). Unlabeled progesterone, testosterone, and 17beta-estradiol had no effect on tritiated glucocorticoid binding in 700 X g supernatant and precipitate fractions from these mammary tissue slices. The 700 X g fractions in mammary tissue slices from all cattle bound cortisol and dexamethasone with high affinity (Kd 10-10M). There were 1263 and 1955 molecules of cortisol and dexamethasone bound per mammary cell, respectively, in mammary tissue slices from lactating non-pregnant cows; in comparison virgin heifers bound 413 and 651 molecules of cortisol and dexamethasone; dry, non-pregnant cows bound 336 and 536 molecules of cortisol and dexamethasone; and 1-mo prepartum nonlactating cows bound 532 molecules of cortisol. Mammary tissue slices from cattle in reproductive states examined contained a major non-specific component which bound cortisol in both 700 X g tissue fractions. Since mammary tissue slices from lactating cattle bound more molecules of glucocorticoids than mammary slices from cattle in other reproductive states, we speculate specific glucorticoid binding may be associated with lactation.     

Expression of messenger ribonucleic acid (mRNA) encoding 3beta-hydroxysteroid dehydrogenase delta4,delta5 isomerase (3beta-HSD) during recruitment and selection of bovine ovarian follicles: identification of dominant follicles by expression of 3beta-HSD mRNA within the granulosa cell layer

The objective of the present study was to examine changes in expression of mRNA encoding 3beta-hydroxysteroid dehydrogenase delta4,delta5 isomerase (3beta-HSD) during recruitment and selection of bovine ovarian follicles. Dairy heifers (4-5/time period) were ovariectomized at 12, 24, 36, 48, 60, 72, 84, or 96 h after initiation of the first follicular wave (Time 0) following estrus. Expression of 3beta-HSD mRNA was localized by in situ hybridization and quantified by image analysis. Expression of 3beta-HSD mRNA was first detected in theca interna cells of preantral follicles with a well-developed theca layer and in granulosa cells of follicles > or = 8 mm in diameter. Regardless of stage of follicular wave, expression of 3beta-HSD mRNA in granulosa cells of follicles > or = 8 mm was correlated with follicular size (r = 0.665; p < 0.01). The 36-h time period appeared to be a transition period for selection since dominant follicles were detected by size and expression of 3beta-HSD mRNA in some cows but not in others. By 48 h after wave initiation, dominant follicles could be identified by both size and expression of 3beta-HSD mRNA. Expression of mRNA for 3beta-HSD in theca cells was higher (p < 0.05) at 24 h than at 12 h and remained elevated thereafter through 96 h. In contrast to theca cells, expression of mRNA for 3beta-HSD was undetectable within granulosa cells at 12 and 24 h. At 36 h, 3beta-HSD mRNA was expressed in granulosa cells of healthy follicles > or = 8 mm, and expression was higher (p < 0.05) at 48 h compared with 36 h. Expression of 3beta-HSD mRNA levels increased further in granulosa cells (p < 0.05) at 84 and 96 h compared to 48 h. Upon detection of mRNA for 3beta-HSD in granulosa cells, high levels of expression were always found in one (dominant) follicle/cow with the exception of two cows at 36 and 84 h that expressed 3beta-HSD mRNA in two large healthy follicles. Expression of 3beta-HSD mRNA was also detectable in granulosa cells of a few large atretic follicles in which remnant granulosa cells appeared to be luteinized. Healthy follicles expressed higher (p < 0.05) levels of 3beta-HSD mRNA in both theca and granulosa cells than did atretic follicles. Expression of 3beta-HSD mRNA in theca cells was higher (p < 0.01) in dominant follicles than in other subordinate healthy follicles. These results indicate that only selected dominant follicles express 3beta-HSD mRNA within granulosa cells, and expression increased in both thecal and granulosa cells during the follicular wave. Therefore, expression of 3beta-HSD mRNA within granulosa cells may be associated with the mechanism of selection of the dominant follicle during a follicular wave and may be required for maximum steroid production during follicular dominance.     

宁夏扶贫扬黄灌溉工程盐渍土盐胀特性及对工程破坏的影响研究

针对宁夏扶贫扬黄灌溉工程固海扩灌第四泵站及干渠硫酸盐盐渍土的盐胀规律及特性进行研究,主要是分析硫酸盐盐渍土对水利工程混凝土构筑物的破坏机理,通过现场取样并在室内进行单次降温膨胀试验,得出了硫酸盐盐渍土盐胀特性及其影响因素.盐渍土膨胀变形与土中硫酸钠含量的增加、初始干密度的增大、温度的降低密切相关,剧烈膨胀变形的温度区间集中在15～-5℃     

电力系统动态仿真的一种改进迭代算法

基于电力系统动态仿真计算中微分方程与代数方程的交替迭代算法,提出了一种新的混合式迭代解法。该方法的基本原理是在延续了电力系统模块化建模及迭代算法特点前提下,将微分方程的求解方法多样化。仿真结果证明,混合式迭代解法应用在电力系统动态仿真计算中,计算结果正确,突破了传统的电力系统各模块计算时使用单一的数值解法的局限。     

最小二乘法在多传感器测量标定中的应用

在工程实际应用中建立起多变量测量的数学模型,为了给定数学模型中的系数参数,引入了最小二乘法的思想.根据最小二乘法的求解原理,建立了一种适用于多变量方程组系数参数的拟合算法.在多传感器测量标定和数据处理中加以应用,提高了计算精度.通过将其与一般算法进行比较,体现了最小二乘法的优越性.     

Collective sensing and collective responses in quorum-sensing bacteria

Bacteria often face fluctuating environments, and in response many species have evolved complex decision-making mechanisms to match their behaviour to the prevailing conditions. Some environmental cues provide direct and reliable information (such as nutrient concentrations) and can be responded to individually. Other environmental parameters are harder to infer and require a collective mechanism of sensing. In addition, some environmental challenges are best faced by a group of cells rather than an individual. In this review, we discuss how bacteria sense and overcome environmental challenges as a group using collective mechanisms of sensing, known as ‘quorum sensing’ (QS). QS is characterized by the release and detection of small molecules, potentially allowing individuals to infer environmental parameters such as density and mass transfer. While a great deal of the molecular mechanisms of QS have been described, there is still controversy over its functional role. We discuss what QS senses and how, what it controls and why, and how social dilemmas shape its evolution. Finally, there is a growing focus on the use of QS inhibitors as antibacterial chemotherapy. We discuss the claim that such a strategy could overcome the evolution of resistance. By linking existing theoretical approaches to data, we hope this review will spur greater collaboration between experimental and theoretical researchers.