On selection of forwarding nodes for long opportunistic routes

Opportunistic routing is a promising routing paradigm which increases the network throughput. It forces the sender’s neighbors, who successfully overheard the transmitted packet, to participate in the packet forwarding process as intermediate forwarding nodes. As a seminal opportunistic routing protocol, MORE combines network coding idea with opportunistic routing to eliminate the need for strict coordination among active forwarding nodes. In this paper, we show that MORE performance does not scale well with the route length, especially when the route length goes beyond two hops. Also, we found that MORE fails to establish a working opportunistic route in sparse networks. Clearly, the network throughput is directly influenced by both the quantity and quality of forwarding nodes, and their cooperation order. In this paper, we propose a new forwarder selection mechanism which considers the route length, link qualities, the distance from the source, and nodes density. It eliminates the occasional route disconnectivity happening in MORE and improves the quality of the established opportunistic routes. The simulation result indicates that our proposal always outperforms MORE when dealing with long opportunistic routes.

     

QoS Guaranteed Resource Allocation Scheme for Cognitive Femtocells in LTE Heterogeneous Networks with Universal Frequency Reuse

In this paper, we propose a novel resource allocation scheme for co-channel interference avoidance in LTE heterogeneous networks with universal spectrum reuse where both macro users (MUs) and cognitive femto base stations (FBSs) within the same macrocell coverage can dynamically reuse whole spectrum. Specifically, resource blocks (RBs) are shared between cognitive FBSs in underlay mode while the resource sharing among FBSs and MUs is in overlay mode. The macrocell is divided into inner and outer regions with the inner region further divided into three sectors. The proposed scheme addresses co-channel interference (CCI) by employing fractional frequency reuse (FFR) for RB allocation in the outer region of the macrocell and increase the distance of users that reuse the same RB within the macrocell. Part of RBs are allocated to the outer region of the macrocell with a FFR factor of 1/3, while the remaining RBs are dynamically allocated to each sector in the inner region of macrocell based on MUs demand to efficiently utilize the available spectrum. A basic macro base station (MBS) assistance is required by the FBS in selection of suitable RB to avoid interference with MU in each sector. With the proposed solution, both macro and femto users can dynamically access the whole spectrum while having minimum bandwidth guarantee even under fully congested scenarios. Moreover, the proposed scheme practically eliminates the cross-tier interference and the CCI problem in heterogeneous network reduces to inter-femtocell interference. The throughput and outage performances of the proposed scheme are validated through extensive simulations under LTE network parameters. Simulation results show that the proposed scheme achieves a performance gain of more than 1.5 dB in terms of SINRs of both macro user and femto user compared to traditional cognitive and non-cognitive schemes without bandwidth guarantee for femtocells.     

Enhancement of in vitro antitumour activity of epirubicin in HER2+ breast cancer cells using immunoliposome formulation

Epirubicin (EPI) is one of the potent breast cancer (BC) chemotherapeutic agents, but its adverse effects limit its efficacy. Herein, EPI was selected to be loaded in liposomal carrier, which has been targeted by a monoclonal antibody, Herceptin. The preparation process of liposomes was a modified ethanol injection method followed by Herceptin conjugation. The in vitro cell toxicity and cellular uptake of optimum formulation against HER2+ and HER2− cancer cell lines were evaluated. The results showed that the drug loading (DL%) and encapsulation efficiency (EE%) of liposome preparation method yielded 30.62% ± 0.49% and 62.39% ± 8.75%, respectively. The average size of naked liposomes (EPI‐Lipo) and immunoliposomes (EPI‐Lipo‐mAb) was 234 ± 9.86 and 257.26 ± 6.25 nm, with a relatively monodisperse distribution, which was confirmed by SEM micrographs. The release kinetic followed Higuchi model for both naked and immunoliposomes. In vitro cytotoxicity study on three different BC cell lines including BT‐20, MDA‐MB‐453 and MCF‐7 demonstrated higher toxicity of EPI in the Herceptin conjugated form (EPI‐Lipo‐mAb) in comparison with the free EPI and EPI‐Lipo in HER2 overexpressing cell line. In addition, the cellular uptake study showed a higher uptake of immunoliposomes by MCF‐7 cells in comparison with naked liposomes. In conclusion, these data show that the targeted delivery of EPI to breast cancer cells can be achieved by EPI‐Lipo‐mAb in vitro, and this strategy could be used for breast cancer therapy with further studies.     

A numerical study to investigate the influence of surface roughness and boundary condition on the shear behaviour of rock joints

Bulletin of Engineering Geology and the Environment - The shear behaviours of rock joints with and without rock bolt support are numerically studied using the discrete element code PFC2D. A...     

Comparison Study of Fourier and SVD Method for Plasma Mode Analysis in Tokamaks

Fourier analysis and Singular Value Decomposition (SVD) are two familiar methods for mode detection in tokamaks. In this article this two methods, fourier and SVD, have compared. The results show fourier analysis in m ≥ 3 and when the energy is balanced between modes could not recognize the correct mode number. The SVD analysis is cited method for all modes.     

Prediction of Particle Deposition Using a Simplified Particle Model in Fully Developed Channel Flow

In this study the Eulerian particle model was modified to predict the particle deposition rate in fully developed channel flow. The modified model is less complicated and has much lower computation time. The performance of the simplified model was examined by comparing the particle deposition rate in a vertical channel with the experimental data for fully developed channel flow available in the literature. The effects of turbophoretic force, thermophoretic force, electrostatic force, gravitational force, Brownian/turbulent diffusion, and the wall roughness on the particle deposition rate were examined. The predictions of the modified particle model were in agreement with the experimental data.     

An investigation on the dose-dependent effect of iron shaving on bio-hydrogen production from food waste

Bio-hydrogen production is of significant interest as it is capable of consuming waste material and synthesizing hydrogen which is a green gas. In this study, we examined the dose-dependent effect of iron shaving on bio-hydrogen production from an integrated dark and photo fermentation system from an artificial food waste. Overall, introduction of iron shaving enhanced the bio-gas production. Statistical analysis was performed on the extracted parameters obtained from fitting the experimental data to Gompertz function, revealing that the bio-gas production can be significantly enhanced by addition of iron shaving at concentrations up to 500 mg/L, with a maximum enhancement at 200 mg/mL. GC analysis showed that introduction of iron shaving at 200 mg/L also maximized the hydrogen percentage in the produced bio-gas. Based on the HPLC results, it was postulated that the dark-fermentation step was probably the step that was more affected by the introduction of iron shaving. Investigation of the pH showed that the acidification of the solution approximately coincided with the termination of the process. Our finding suggests that a more efficient buffer-assisted setup can significantly enhance the bio-hydrogen efficiency.     

Analysis of shear rate effects on drag reduction in turbulent channel flow with superhydrophobic wall

We examined the shear rate effect on drag reduction of superhydrophobic surfaces with different slip lengths. For this purpose, turbulent channel flow was considered at the friction Reynolds numbers of Reτ = 180, 395, 500. By using Navier＇s slip condition it is shown that increasing shear rate leads to the greater reduction in drag force and also more reduction occurs in larger slip length. Based on the results, more than 25% drag reduction happens at a friction Reynolds number of Reτ= 500 for slip length of 1 ×10 5 m. The simulation results suggest that reduction in drag force occurs because slip condition reduces the Reynolds stresses, also weakens vorticity filed and the near-wall coherent structures, and therefore turbulence production is decreased.     

Management of sustainable manufacturing systems-a review on mathematical problems

The ever-growing awareness of environmental protection has significantly influenced the method of manufacturing products. Due to the introduction of new processes, the management of sustainable manufacturing shows different characteristics to those of traditional systems. Sustainable manufacturing systems have attracted a great deal of attention in the past 20 years as an emerging manufacturing approach. Particularly in the last 10 years, the number of papers focusing on the topic of sustainable manufacturing systems’ management has increased rapidly. More and more practical factors have been considered and integrated into this area which makes it more complex, but closer to reality. This paper aims to classify the mathematical problems dealing with the management of sustainable manufacturing systems. More than 100 related papers mainly from 1994 to 2015 have been selected and reviewed and divided into three categories according to the main elements in a manufacturing system: production planning and control, inventory management and control and manufacturing network design. The development of each category is summarised and the corresponding mathematical problems are discussed to provide a general overview of the relevant research fields and identify future research directions.